| Full name: F-box and leucine rich repeat protein 15 | Alias Symbol: MGC11279|Fbl15 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 79176 | HGNC ID: HGNC:28155 | Ensembl Gene: ENSG00000107872 | OMIM ID: 610287 |
Expression of FBXL15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXL15 | 79176 | 218938_at | 0.0204 | 0.9779 | |
| GSE20347 | FBXL15 | 79176 | 218938_at | -0.2428 | 0.0986 | |
| GSE23400 | FBXL15 | 79176 | 218938_at | -0.0681 | 0.1659 | |
| GSE26886 | FBXL15 | 79176 | 218938_at | 0.4965 | 0.0155 | |
| GSE29001 | FBXL15 | 79176 | 218938_at | -0.0342 | 0.8876 | |
| GSE38129 | FBXL15 | 79176 | 218938_at | -0.1774 | 0.3772 | |
| GSE45670 | FBXL15 | 79176 | 218938_at | -0.1118 | 0.2741 | |
| GSE53622 | FBXL15 | 79176 | 71788 | -0.1071 | 0.0282 | |
| GSE53624 | FBXL15 | 79176 | 71788 | -0.0651 | 0.1751 | |
| GSE63941 | FBXL15 | 79176 | 218938_at | -0.5264 | 0.1501 | |
| GSE77861 | FBXL15 | 79176 | 218938_at | -0.0414 | 0.7411 | |
| GSE97050 | FBXL15 | 79176 | A_23_P12635 | 0.0769 | 0.6998 | |
| SRP007169 | FBXL15 | 79176 | RNAseq | -1.2154 | 0.0088 | |
| SRP008496 | FBXL15 | 79176 | RNAseq | -0.6782 | 0.0639 | |
| SRP064894 | FBXL15 | 79176 | RNAseq | -0.2645 | 0.4325 | |
| SRP133303 | FBXL15 | 79176 | RNAseq | -0.4102 | 0.0088 | |
| SRP159526 | FBXL15 | 79176 | RNAseq | -0.2159 | 0.3923 | |
| SRP193095 | FBXL15 | 79176 | RNAseq | -0.3856 | 0.0033 | |
| SRP219564 | FBXL15 | 79176 | RNAseq | -0.0084 | 0.9854 | |
| TCGA | FBXL15 | 79176 | RNAseq | -0.1904 | 0.0052 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FBXL15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXL15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXL15 | 79176 | 2 | 9 | 19 | |
| GSE20123 | FBXL15 | 79176 | 2 | 8 | 20 | |
| GSE43470 | FBXL15 | 79176 | 0 | 8 | 35 | |
| GSE46452 | FBXL15 | 79176 | 0 | 11 | 48 | |
| GSE47630 | FBXL15 | 79176 | 2 | 14 | 24 | |
| GSE54993 | FBXL15 | 79176 | 8 | 0 | 62 | |
| GSE54994 | FBXL15 | 79176 | 1 | 11 | 41 | |
| GSE60625 | FBXL15 | 79176 | 0 | 0 | 11 | |
| GSE74703 | FBXL15 | 79176 | 0 | 5 | 31 | |
| GSE74704 | FBXL15 | 79176 | 1 | 4 | 15 | |
| TCGA | FBXL15 | 79176 | 6 | 28 | 62 |
Total number of gains: 22; Total number of losses: 98; Total Number of normals: 368.
Somatic mutations of FBXL15:
Generating mutation plots.
Highly correlated genes for FBXL15:
Showing top 20/107 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXL15 | LRFN2 | 0.771672 | 3 | 0 | 3 |
| FBXL15 | LY6G5C | 0.756819 | 3 | 0 | 3 |
| FBXL15 | STK16 | 0.745661 | 3 | 0 | 3 |
| FBXL15 | FERD3L | 0.740315 | 3 | 0 | 3 |
| FBXL15 | GNB1L | 0.731433 | 3 | 0 | 3 |
| FBXL15 | SLC6A3 | 0.714434 | 4 | 0 | 4 |
| FBXL15 | SLC27A5 | 0.711361 | 3 | 0 | 3 |
| FBXL15 | PLB1 | 0.70799 | 3 | 0 | 3 |
| FBXL15 | KLHL26 | 0.706737 | 4 | 0 | 4 |
| FBXL15 | SYCE3 | 0.706204 | 3 | 0 | 3 |
| FBXL15 | HIRIP3 | 0.701644 | 3 | 0 | 3 |
| FBXL15 | RAD51D | 0.696109 | 3 | 0 | 3 |
| FBXL15 | ZNF182 | 0.693219 | 3 | 0 | 3 |
| FBXL15 | AANAT | 0.688876 | 4 | 0 | 3 |
| FBXL15 | AGPAT1 | 0.686033 | 4 | 0 | 3 |
| FBXL15 | ZNF428 | 0.684078 | 4 | 0 | 3 |
| FBXL15 | SLC41A3 | 0.676157 | 3 | 0 | 3 |
| FBXL15 | PSPN | 0.671423 | 3 | 0 | 3 |
| FBXL15 | TMCO3 | 0.669076 | 3 | 0 | 3 |
| FBXL15 | AKR7A3 | 0.663127 | 3 | 0 | 3 |
For details and further investigation, click here
