MED13

 

Full name: mediator complex subunit 13 Alias Symbol: KIAA0593|TRAP240
Type: protein-coding gene Cytoband: 17q23.2
Entrez ID: 9969 HGNC ID: HGNC:22474 Ensembl Gene: ENSG00000108510 OMIM ID: 603808
Drug and gene relationship at DGIdb

 

Expression of MED13:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MED13 9969 201987_at 0.0998 0.6837
GSE20347 MED13 9969 201987_at 0.0209 0.8791
GSE23400 MED13 9969 201987_at 0.0753 0.3198
GSE26886 MED13 9969 201987_at 0.4162 0.0103
GSE29001 MED13 9969 201987_at 0.1521 0.3835
GSE38129 MED13 9969 201987_at 0.0469 0.6808
GSE45670 MED13 9969 201987_at 0.0327 0.8206
GSE53622 MED13 9969 26528 -0.0685 0.1953
GSE53624 MED13 9969 26528 0.1127 0.0334
GSE63941 MED13 9969 201987_at -0.9029 0.0425
GSE77861 MED13 9969 201987_at 0.5747 0.0599
GSE97050 MED13 9969 A_33_P3223759 -0.1408 0.4794
SRP007169 MED13 9969 RNAseq 0.1885 0.5198
SRP008496 MED13 9969 RNAseq 0.3030 0.0389
SRP064894 MED13 9969 RNAseq -0.1585 0.4484
SRP133303 MED13 9969 RNAseq 0.5113 0.0020
SRP159526 MED13 9969 RNAseq 0.0431 0.7979
SRP193095 MED13 9969 RNAseq -0.0762 0.1514
SRP219564 MED13 9969 RNAseq -0.3472 0.3198
TCGA MED13 9969 RNAseq 0.0106 0.8105

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MED13 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MED13:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MED13 9969 4 1 25
GSE20123 MED13 9969 4 1 25
GSE43470 MED13 9969 5 0 38
GSE46452 MED13 9969 31 0 28
GSE47630 MED13 9969 7 1 32
GSE54993 MED13 9969 2 5 63
GSE54994 MED13 9969 9 5 39
GSE60625 MED13 9969 4 0 7
GSE74703 MED13 9969 5 0 31
GSE74704 MED13 9969 3 1 16
TCGA MED13 9969 31 6 59

Total number of gains: 105; Total number of losses: 20; Total Number of normals: 363.  


 

Somatic mutations of MED13:

 

Generating mutation plots.

 

Highly correlated genes for MED13:

 

Showing top 20/424 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MED13U2SURP0.758441303
MED13KIAA07530.751621303
MED13ZXDC0.751467303
MED13GLS0.750039303
MED13SPSB20.741721303
MED13CUL70.740305404
MED13MEA10.736837303
MED13CHERP0.735438404
MED13RRAS20.7341303
MED13DNAJC130.733978303
MED13ZBTB390.73155404
MED13GNA130.730194505
MED13ZNF2600.727835403
MED13NVL0.72619303
MED13DHX400.726002404
MED13ZNF3970.724959303
MED13ITGAV0.723364303
MED13NOL90.723081303
MED13SNAPC40.722937303
MED13PIK3R30.722188303

For details and further investigation, click here