| Full name: cullin 7 | Alias Symbol: dJ20C7.5 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 9820 | HGNC ID: HGNC:21024 | Ensembl Gene: ENSG00000044090 | OMIM ID: 609577 |
| Drug and gene relationship at DGIdb | |||
Expression of CUL7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CUL7 | 9820 | 36084_at | 0.2379 | 0.4319 | |
| GSE20347 | CUL7 | 9820 | 36084_at | 0.1503 | 0.0900 | |
| GSE23400 | CUL7 | 9820 | 36084_at | 0.1245 | 0.0009 | |
| GSE26886 | CUL7 | 9820 | 36084_at | 0.3429 | 0.0427 | |
| GSE29001 | CUL7 | 9820 | 36084_at | -0.0246 | 0.8910 | |
| GSE38129 | CUL7 | 9820 | 36084_at | 0.2137 | 0.0369 | |
| GSE45670 | CUL7 | 9820 | 36084_at | 0.0744 | 0.3175 | |
| GSE53622 | CUL7 | 9820 | 25743 | 0.2646 | 0.0001 | |
| GSE53624 | CUL7 | 9820 | 25743 | 0.2648 | 0.0008 | |
| GSE63941 | CUL7 | 9820 | 36084_at | 0.5068 | 0.0214 | |
| GSE77861 | CUL7 | 9820 | 36084_at | 0.0161 | 0.9313 | |
| GSE97050 | CUL7 | 9820 | A_23_P19348 | 0.2434 | 0.3291 | |
| SRP007169 | CUL7 | 9820 | RNAseq | 0.7512 | 0.0646 | |
| SRP008496 | CUL7 | 9820 | RNAseq | 0.6312 | 0.0594 | |
| SRP064894 | CUL7 | 9820 | RNAseq | 0.9232 | 0.0000 | |
| SRP133303 | CUL7 | 9820 | RNAseq | 0.1316 | 0.4099 | |
| SRP159526 | CUL7 | 9820 | RNAseq | 0.8003 | 0.0079 | |
| SRP193095 | CUL7 | 9820 | RNAseq | 0.3357 | 0.0179 | |
| SRP219564 | CUL7 | 9820 | RNAseq | 0.8179 | 0.0111 | |
| TCGA | CUL7 | 9820 | RNAseq | -0.0742 | 0.2266 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CUL7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CUL7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CUL7 | 9820 | 7 | 0 | 23 | |
| GSE20123 | CUL7 | 9820 | 7 | 0 | 23 | |
| GSE43470 | CUL7 | 9820 | 6 | 0 | 37 | |
| GSE46452 | CUL7 | 9820 | 2 | 9 | 48 | |
| GSE47630 | CUL7 | 9820 | 8 | 4 | 28 | |
| GSE54993 | CUL7 | 9820 | 3 | 2 | 65 | |
| GSE54994 | CUL7 | 9820 | 11 | 4 | 38 | |
| GSE60625 | CUL7 | 9820 | 0 | 1 | 10 | |
| GSE74703 | CUL7 | 9820 | 6 | 0 | 30 | |
| GSE74704 | CUL7 | 9820 | 3 | 0 | 17 | |
| TCGA | CUL7 | 9820 | 21 | 13 | 62 |
Total number of gains: 74; Total number of losses: 33; Total Number of normals: 381.
Somatic mutations of CUL7:
Generating mutation plots.
Highly correlated genes for CUL7:
Showing top 20/454 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CUL7 | SENP3 | 0.818478 | 3 | 0 | 3 |
| CUL7 | TATDN2 | 0.791908 | 3 | 0 | 3 |
| CUL7 | PNPLA6 | 0.767125 | 4 | 0 | 3 |
| CUL7 | FAM53B | 0.749861 | 3 | 0 | 3 |
| CUL7 | COPE | 0.749183 | 4 | 0 | 4 |
| CUL7 | ZNF766 | 0.748872 | 3 | 0 | 3 |
| CUL7 | ABHD16A | 0.747721 | 3 | 0 | 3 |
| CUL7 | MED13 | 0.740305 | 4 | 0 | 4 |
| CUL7 | OS9 | 0.739495 | 4 | 0 | 4 |
| CUL7 | SMARCC1 | 0.735654 | 3 | 0 | 3 |
| CUL7 | ELP2 | 0.735222 | 3 | 0 | 3 |
| CUL7 | LEMD2 | 0.734571 | 4 | 0 | 4 |
| CUL7 | LDLRAP1 | 0.728833 | 3 | 0 | 3 |
| CUL7 | SMARCD2 | 0.724963 | 3 | 0 | 3 |
| CUL7 | SLFNL1 | 0.723146 | 3 | 0 | 3 |
| CUL7 | CFL1 | 0.720577 | 3 | 0 | 3 |
| CUL7 | TNP2 | 0.720471 | 3 | 0 | 3 |
| CUL7 | MBTPS1 | 0.719237 | 3 | 0 | 3 |
| CUL7 | KHSRP | 0.717585 | 3 | 0 | 3 |
| CUL7 | TNFRSF9 | 0.717439 | 4 | 0 | 4 |
For details and further investigation, click here
