| Full name: nuclear VCP like | Alias Symbol: NVL2 | ||
| Type: protein-coding gene | Cytoband: 1q42.11 | ||
| Entrez ID: 4931 | HGNC ID: HGNC:8070 | Ensembl Gene: ENSG00000143748 | OMIM ID: 602426 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NVL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NVL | 4931 | 207877_s_at | 0.5623 | 0.0801 | |
| GSE20347 | NVL | 4931 | 207877_s_at | 0.6296 | 0.0000 | |
| GSE23400 | NVL | 4931 | 207877_s_at | 0.2129 | 0.0000 | |
| GSE26886 | NVL | 4931 | 207877_s_at | 0.5809 | 0.0207 | |
| GSE29001 | NVL | 4931 | 207877_s_at | 0.4944 | 0.0603 | |
| GSE38129 | NVL | 4931 | 207877_s_at | 0.5666 | 0.0000 | |
| GSE45670 | NVL | 4931 | 207877_s_at | 0.5447 | 0.0001 | |
| GSE53622 | NVL | 4931 | 101220 | 0.4247 | 0.0000 | |
| GSE53624 | NVL | 4931 | 101220 | 0.7211 | 0.0000 | |
| GSE63941 | NVL | 4931 | 207877_s_at | 0.4937 | 0.1559 | |
| GSE77861 | NVL | 4931 | 207877_s_at | 0.5623 | 0.0094 | |
| GSE97050 | NVL | 4931 | A_23_P96990 | -0.0410 | 0.9161 | |
| SRP007169 | NVL | 4931 | RNAseq | 0.6898 | 0.1439 | |
| SRP008496 | NVL | 4931 | RNAseq | 0.7580 | 0.0441 | |
| SRP064894 | NVL | 4931 | RNAseq | 0.5642 | 0.0000 | |
| SRP133303 | NVL | 4931 | RNAseq | 0.4919 | 0.0000 | |
| SRP159526 | NVL | 4931 | RNAseq | 0.5071 | 0.1065 | |
| SRP193095 | NVL | 4931 | RNAseq | 0.4682 | 0.0000 | |
| SRP219564 | NVL | 4931 | RNAseq | 0.6456 | 0.0385 | |
| TCGA | NVL | 4931 | RNAseq | 0.1930 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NVL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NVL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NVL | 4931 | 10 | 0 | 20 | |
| GSE20123 | NVL | 4931 | 10 | 0 | 20 | |
| GSE43470 | NVL | 4931 | 7 | 0 | 36 | |
| GSE46452 | NVL | 4931 | 3 | 1 | 55 | |
| GSE47630 | NVL | 4931 | 15 | 0 | 25 | |
| GSE54993 | NVL | 4931 | 0 | 6 | 64 | |
| GSE54994 | NVL | 4931 | 16 | 0 | 37 | |
| GSE60625 | NVL | 4931 | 0 | 0 | 11 | |
| GSE74703 | NVL | 4931 | 7 | 0 | 29 | |
| GSE74704 | NVL | 4931 | 4 | 0 | 16 | |
| TCGA | NVL | 4931 | 45 | 4 | 47 |
Total number of gains: 117; Total number of losses: 11; Total Number of normals: 360.
Somatic mutations of NVL:
Generating mutation plots.
Highly correlated genes for NVL:
Showing top 20/1829 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NVL | C20orf194 | 0.870024 | 3 | 0 | 3 |
| NVL | SLC39A3 | 0.826969 | 3 | 0 | 3 |
| NVL | ANKRD27 | 0.789721 | 3 | 0 | 3 |
| NVL | DUSP23 | 0.775935 | 3 | 0 | 3 |
| NVL | DAG1 | 0.761194 | 3 | 0 | 3 |
| NVL | SCNM1 | 0.760424 | 3 | 0 | 3 |
| NVL | TYW5 | 0.759395 | 3 | 0 | 3 |
| NVL | NACC1 | 0.755174 | 3 | 0 | 3 |
| NVL | TMEM63B | 0.747838 | 4 | 0 | 4 |
| NVL | FLVCR1 | 0.745351 | 7 | 0 | 7 |
| NVL | PDCD2L | 0.745134 | 6 | 0 | 5 |
| NVL | GORAB | 0.745118 | 7 | 0 | 7 |
| NVL | EVI5L | 0.743279 | 3 | 0 | 3 |
| NVL | PIAS3 | 0.742867 | 3 | 0 | 3 |
| NVL | ZNF397 | 0.742304 | 3 | 0 | 3 |
| NVL | COG2 | 0.742031 | 13 | 0 | 12 |
| NVL | ZNF579 | 0.740363 | 3 | 0 | 3 |
| NVL | NXF1 | 0.737113 | 3 | 0 | 3 |
| NVL | PKN1 | 0.736414 | 3 | 0 | 3 |
| NVL | ZBTB37 | 0.736247 | 4 | 0 | 3 |
For details and further investigation, click here
