| Full name: small nuclear RNA activating complex polypeptide 4 | Alias Symbol: SNAP190|PTFalpha|FLJ13451 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 6621 | HGNC ID: HGNC:11137 | Ensembl Gene: ENSG00000165684 | OMIM ID: 602777 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SNAPC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNAPC4 | 6621 | 215926_x_at | 0.3153 | 0.4220 | |
| GSE20347 | SNAPC4 | 6621 | 215926_x_at | 0.1247 | 0.1489 | |
| GSE23400 | SNAPC4 | 6621 | 215926_x_at | 0.1145 | 0.0028 | |
| GSE26886 | SNAPC4 | 6621 | 215926_x_at | 0.6230 | 0.0000 | |
| GSE29001 | SNAPC4 | 6621 | 215926_x_at | 0.2382 | 0.2573 | |
| GSE38129 | SNAPC4 | 6621 | 215926_x_at | 0.1974 | 0.0172 | |
| GSE45670 | SNAPC4 | 6621 | 215926_x_at | 0.2532 | 0.0072 | |
| GSE53622 | SNAPC4 | 6621 | 123983 | 0.2560 | 0.0103 | |
| GSE53624 | SNAPC4 | 6621 | 123983 | 0.7873 | 0.0000 | |
| GSE63941 | SNAPC4 | 6621 | 215926_x_at | -0.0287 | 0.9054 | |
| GSE77861 | SNAPC4 | 6621 | 215926_x_at | -0.0045 | 0.9702 | |
| GSE97050 | SNAPC4 | 6621 | A_23_P20722 | 0.0965 | 0.6426 | |
| SRP007169 | SNAPC4 | 6621 | RNAseq | 1.0167 | 0.1658 | |
| SRP064894 | SNAPC4 | 6621 | RNAseq | 0.9319 | 0.0000 | |
| SRP133303 | SNAPC4 | 6621 | RNAseq | 0.3777 | 0.0327 | |
| SRP159526 | SNAPC4 | 6621 | RNAseq | 0.9940 | 0.0250 | |
| SRP193095 | SNAPC4 | 6621 | RNAseq | 0.8405 | 0.0000 | |
| SRP219564 | SNAPC4 | 6621 | RNAseq | 0.8669 | 0.0536 | |
| TCGA | SNAPC4 | 6621 | RNAseq | 0.1274 | 0.0350 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNAPC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNAPC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNAPC4 | 6621 | 4 | 7 | 19 | |
| GSE20123 | SNAPC4 | 6621 | 4 | 7 | 19 | |
| GSE43470 | SNAPC4 | 6621 | 3 | 7 | 33 | |
| GSE46452 | SNAPC4 | 6621 | 6 | 13 | 40 | |
| GSE47630 | SNAPC4 | 6621 | 6 | 15 | 19 | |
| GSE54993 | SNAPC4 | 6621 | 3 | 3 | 64 | |
| GSE54994 | SNAPC4 | 6621 | 13 | 7 | 33 | |
| GSE60625 | SNAPC4 | 6621 | 0 | 0 | 11 | |
| GSE74703 | SNAPC4 | 6621 | 3 | 5 | 28 | |
| GSE74704 | SNAPC4 | 6621 | 2 | 5 | 13 | |
| TCGA | SNAPC4 | 6621 | 29 | 24 | 43 |
Total number of gains: 73; Total number of losses: 93; Total Number of normals: 322.
Somatic mutations of SNAPC4:
Generating mutation plots.
Highly correlated genes for SNAPC4:
Showing top 20/846 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNAPC4 | TRIM47 | 0.865215 | 3 | 0 | 3 |
| SNAPC4 | SEMA3A | 0.810643 | 3 | 0 | 3 |
| SNAPC4 | SORBS3 | 0.803553 | 3 | 0 | 3 |
| SNAPC4 | SLC39A3 | 0.803265 | 4 | 0 | 4 |
| SNAPC4 | EFEMP2 | 0.782275 | 3 | 0 | 3 |
| SNAPC4 | EVL | 0.763765 | 3 | 0 | 3 |
| SNAPC4 | ZNF669 | 0.75682 | 3 | 0 | 3 |
| SNAPC4 | TBCB | 0.745052 | 3 | 0 | 3 |
| SNAPC4 | FAM89B | 0.738871 | 3 | 0 | 3 |
| SNAPC4 | RAB11B | 0.734497 | 3 | 0 | 3 |
| SNAPC4 | PKN3 | 0.72644 | 5 | 0 | 4 |
| SNAPC4 | PLEKHA4 | 0.723954 | 5 | 0 | 4 |
| SNAPC4 | MED13 | 0.722937 | 3 | 0 | 3 |
| SNAPC4 | TGFB1I1 | 0.719497 | 3 | 0 | 3 |
| SNAPC4 | ARAF | 0.718781 | 3 | 0 | 3 |
| SNAPC4 | RICTOR | 0.715283 | 3 | 0 | 3 |
| SNAPC4 | BRAT1 | 0.715195 | 4 | 0 | 4 |
| SNAPC4 | MFGE8 | 0.713731 | 4 | 0 | 4 |
| SNAPC4 | RHOBTB2 | 0.712894 | 3 | 0 | 3 |
| SNAPC4 | SETD5 | 0.707837 | 4 | 0 | 4 |
For details and further investigation, click here
