| Full name: MLLT1 super elongation complex subunit | Alias Symbol: ENL|LTG19|YEATS1 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 4298 | HGNC ID: HGNC:7134 | Ensembl Gene: ENSG00000130382 | OMIM ID: 159556 |
| Drug and gene relationship at DGIdb | |||
Expression of MLLT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MLLT1 | 4298 | 224993_at | 0.3450 | 0.3985 | |
| GSE20347 | MLLT1 | 4298 | 214477_at | -0.1280 | 0.0549 | |
| GSE23400 | MLLT1 | 4298 | 214477_at | -0.0991 | 0.0014 | |
| GSE26886 | MLLT1 | 4298 | 224993_at | 0.4017 | 0.0277 | |
| GSE29001 | MLLT1 | 4298 | 214477_at | -0.0531 | 0.6502 | |
| GSE38129 | MLLT1 | 4298 | 214477_at | -0.0555 | 0.4232 | |
| GSE45670 | MLLT1 | 4298 | 224993_at | 0.0737 | 0.5441 | |
| GSE53622 | MLLT1 | 4298 | 143057 | -0.0255 | 0.6448 | |
| GSE53624 | MLLT1 | 4298 | 80570 | 0.2854 | 0.0325 | |
| GSE63941 | MLLT1 | 4298 | 224993_at | -0.4188 | 0.0714 | |
| GSE77861 | MLLT1 | 4298 | 224993_at | 0.1846 | 0.3041 | |
| GSE97050 | MLLT1 | 4298 | A_33_P3289541 | 0.0422 | 0.8465 | |
| SRP007169 | MLLT1 | 4298 | RNAseq | 0.7192 | 0.1276 | |
| SRP008496 | MLLT1 | 4298 | RNAseq | 1.0329 | 0.0006 | |
| SRP064894 | MLLT1 | 4298 | RNAseq | 0.3447 | 0.0463 | |
| SRP133303 | MLLT1 | 4298 | RNAseq | 0.0096 | 0.9553 | |
| SRP159526 | MLLT1 | 4298 | RNAseq | 0.2142 | 0.2503 | |
| SRP193095 | MLLT1 | 4298 | RNAseq | 0.4961 | 0.0002 | |
| SRP219564 | MLLT1 | 4298 | RNAseq | 0.2081 | 0.4824 | |
| TCGA | MLLT1 | 4298 | RNAseq | -0.0644 | 0.1295 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MLLT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MLLT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MLLT1 | 4298 | 5 | 3 | 22 | |
| GSE20123 | MLLT1 | 4298 | 4 | 2 | 24 | |
| GSE43470 | MLLT1 | 4298 | 2 | 6 | 35 | |
| GSE46452 | MLLT1 | 4298 | 47 | 1 | 11 | |
| GSE47630 | MLLT1 | 4298 | 5 | 7 | 28 | |
| GSE54993 | MLLT1 | 4298 | 16 | 3 | 51 | |
| GSE54994 | MLLT1 | 4298 | 6 | 16 | 31 | |
| GSE60625 | MLLT1 | 4298 | 9 | 0 | 2 | |
| GSE74703 | MLLT1 | 4298 | 2 | 4 | 30 | |
| GSE74704 | MLLT1 | 4298 | 1 | 2 | 17 | |
| TCGA | MLLT1 | 4298 | 10 | 19 | 67 |
Total number of gains: 107; Total number of losses: 63; Total Number of normals: 318.
Somatic mutations of MLLT1:
Generating mutation plots.
Highly correlated genes for MLLT1:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MLLT1 | LEMD2 | 0.819356 | 3 | 0 | 3 |
| MLLT1 | ZNF567 | 0.807693 | 3 | 0 | 3 |
| MLLT1 | TYW1 | 0.805482 | 3 | 0 | 3 |
| MLLT1 | ZFX | 0.792594 | 3 | 0 | 3 |
| MLLT1 | AKT1S1 | 0.785998 | 3 | 0 | 3 |
| MLLT1 | PDHA1 | 0.785048 | 3 | 0 | 3 |
| MLLT1 | MRI1 | 0.783 | 3 | 0 | 3 |
| MLLT1 | GYS1 | 0.778256 | 3 | 0 | 3 |
| MLLT1 | HNRNPAB | 0.776413 | 3 | 0 | 3 |
| MLLT1 | ZNF397 | 0.766785 | 3 | 0 | 3 |
| MLLT1 | FBXW8 | 0.766749 | 3 | 0 | 3 |
| MLLT1 | SEC61A1 | 0.763286 | 4 | 0 | 4 |
| MLLT1 | TMSB15B | 0.758909 | 3 | 0 | 3 |
| MLLT1 | MED26 | 0.758169 | 4 | 0 | 4 |
| MLLT1 | RAD18 | 0.757402 | 3 | 0 | 3 |
| MLLT1 | RBM15B | 0.752785 | 3 | 0 | 3 |
| MLLT1 | ZBTB9 | 0.750776 | 3 | 0 | 3 |
| MLLT1 | MRPL21 | 0.750671 | 3 | 0 | 3 |
| MLLT1 | CORO1C | 0.750035 | 3 | 0 | 3 |
| MLLT1 | RBBP7 | 0.746915 | 3 | 0 | 3 |
For details and further investigation, click here
