| Full name: coronin 1C | Alias Symbol: coronin-3|HCRNN4 | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 23603 | HGNC ID: HGNC:2254 | Ensembl Gene: ENSG00000110880 | OMIM ID: 605269 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CORO1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CORO1C | 23603 | 221676_s_at | 0.3209 | 0.3570 | |
| GSE20347 | CORO1C | 23603 | 221676_s_at | 0.9996 | 0.0007 | |
| GSE23400 | CORO1C | 23603 | 221676_s_at | 0.6253 | 0.0000 | |
| GSE26886 | CORO1C | 23603 | 221676_s_at | 0.8014 | 0.0096 | |
| GSE29001 | CORO1C | 23603 | 221676_s_at | 0.7954 | 0.0032 | |
| GSE38129 | CORO1C | 23603 | 221676_s_at | 1.0079 | 0.0000 | |
| GSE45670 | CORO1C | 23603 | 221676_s_at | 0.6259 | 0.0049 | |
| GSE53622 | CORO1C | 23603 | 86761 | 0.0419 | 0.6745 | |
| GSE53624 | CORO1C | 23603 | 86761 | 0.3106 | 0.0004 | |
| GSE63941 | CORO1C | 23603 | 221676_s_at | 0.1210 | 0.8188 | |
| GSE77861 | CORO1C | 23603 | 221676_s_at | 1.0343 | 0.0093 | |
| GSE97050 | CORO1C | 23603 | A_24_P81947 | -0.2109 | 0.4964 | |
| SRP007169 | CORO1C | 23603 | RNAseq | 0.6666 | 0.0781 | |
| SRP008496 | CORO1C | 23603 | RNAseq | 0.8260 | 0.0018 | |
| SRP064894 | CORO1C | 23603 | RNAseq | 0.0165 | 0.9365 | |
| SRP133303 | CORO1C | 23603 | RNAseq | 0.5098 | 0.0047 | |
| SRP159526 | CORO1C | 23603 | RNAseq | 0.6692 | 0.1132 | |
| SRP193095 | CORO1C | 23603 | RNAseq | 0.5886 | 0.0001 | |
| SRP219564 | CORO1C | 23603 | RNAseq | -0.0760 | 0.8504 | |
| TCGA | CORO1C | 23603 | RNAseq | 0.1465 | 0.0068 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CORO1C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CORO1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CORO1C | 23603 | 5 | 3 | 22 | |
| GSE20123 | CORO1C | 23603 | 5 | 4 | 21 | |
| GSE43470 | CORO1C | 23603 | 2 | 1 | 40 | |
| GSE46452 | CORO1C | 23603 | 9 | 1 | 49 | |
| GSE47630 | CORO1C | 23603 | 9 | 1 | 30 | |
| GSE54993 | CORO1C | 23603 | 0 | 5 | 65 | |
| GSE54994 | CORO1C | 23603 | 4 | 2 | 47 | |
| GSE60625 | CORO1C | 23603 | 0 | 0 | 11 | |
| GSE74703 | CORO1C | 23603 | 2 | 0 | 34 | |
| GSE74704 | CORO1C | 23603 | 2 | 2 | 16 | |
| TCGA | CORO1C | 23603 | 21 | 10 | 65 |
Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.
Somatic mutations of CORO1C:
Generating mutation plots.
Highly correlated genes for CORO1C:
Showing top 20/1254 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CORO1C | ICAM5 | 0.815868 | 3 | 0 | 3 |
| CORO1C | LRRC58 | 0.78839 | 3 | 0 | 3 |
| CORO1C | CHCHD7 | 0.774544 | 3 | 0 | 3 |
| CORO1C | MLLT1 | 0.750035 | 3 | 0 | 3 |
| CORO1C | CCDC14 | 0.745952 | 3 | 0 | 3 |
| CORO1C | MRPL48 | 0.739024 | 3 | 0 | 3 |
| CORO1C | REV1 | 0.735048 | 3 | 0 | 3 |
| CORO1C | IL3RA | 0.732359 | 3 | 0 | 3 |
| CORO1C | SPNS1 | 0.726583 | 3 | 0 | 3 |
| CORO1C | WDR54 | 0.726311 | 5 | 0 | 5 |
| CORO1C | STIP1 | 0.725139 | 7 | 0 | 7 |
| CORO1C | ZNF317 | 0.724651 | 3 | 0 | 3 |
| CORO1C | BRD4 | 0.721153 | 4 | 0 | 4 |
| CORO1C | TPCN2 | 0.717099 | 3 | 0 | 3 |
| CORO1C | HSPBP1 | 0.7111 | 3 | 0 | 3 |
| CORO1C | ZFP1 | 0.710927 | 3 | 0 | 3 |
| CORO1C | ZBTB34 | 0.710052 | 3 | 0 | 3 |
| CORO1C | SKA2 | 0.706338 | 3 | 0 | 3 |
| CORO1C | KLF13 | 0.700835 | 4 | 0 | 4 |
| CORO1C | LCLAT1 | 0.70068 | 5 | 0 | 5 |
For details and further investigation, click here
