| Full name: mediator complex subunit 26 | Alias Symbol: CRSP70 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 9441 | HGNC ID: HGNC:2376 | Ensembl Gene: ENSG00000105085 | OMIM ID: 605043 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MED26:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED26 | 9441 | 227538_at | 0.2006 | 0.6717 | |
| GSE26886 | MED26 | 9441 | 227538_at | 0.2522 | 0.1640 | |
| GSE45670 | MED26 | 9441 | 227538_at | 0.1084 | 0.2764 | |
| GSE63941 | MED26 | 9441 | 227538_at | -0.4504 | 0.2148 | |
| GSE77861 | MED26 | 9441 | 227538_at | 0.2082 | 0.0667 | |
| GSE97050 | MED26 | 9441 | A_23_P164737 | -0.1084 | 0.6191 | |
| SRP007169 | MED26 | 9441 | RNAseq | -1.0651 | 0.0152 | |
| SRP008496 | MED26 | 9441 | RNAseq | -0.7481 | 0.0010 | |
| SRP064894 | MED26 | 9441 | RNAseq | -0.0642 | 0.7080 | |
| SRP133303 | MED26 | 9441 | RNAseq | 0.0598 | 0.7175 | |
| SRP159526 | MED26 | 9441 | RNAseq | 0.0443 | 0.8988 | |
| SRP193095 | MED26 | 9441 | RNAseq | -0.0062 | 0.9498 | |
| SRP219564 | MED26 | 9441 | RNAseq | 0.3850 | 0.3320 | |
| TCGA | MED26 | 9441 | RNAseq | 0.0880 | 0.1255 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MED26 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MED26:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED26 | 9441 | 4 | 3 | 23 | |
| GSE20123 | MED26 | 9441 | 3 | 2 | 25 | |
| GSE43470 | MED26 | 9441 | 2 | 6 | 35 | |
| GSE46452 | MED26 | 9441 | 47 | 1 | 11 | |
| GSE47630 | MED26 | 9441 | 4 | 8 | 28 | |
| GSE54993 | MED26 | 9441 | 15 | 4 | 51 | |
| GSE54994 | MED26 | 9441 | 6 | 14 | 33 | |
| GSE60625 | MED26 | 9441 | 9 | 0 | 2 | |
| GSE74703 | MED26 | 9441 | 2 | 4 | 30 | |
| GSE74704 | MED26 | 9441 | 0 | 1 | 19 | |
| TCGA | MED26 | 9441 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 52; Total Number of normals: 327.
Somatic mutations of MED26:
Generating mutation plots.
Highly correlated genes for MED26:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED26 | ZCCHC17 | 0.817752 | 3 | 0 | 3 |
| MED26 | SENP1 | 0.81077 | 3 | 0 | 3 |
| MED26 | EXOC6 | 0.797911 | 3 | 0 | 3 |
| MED26 | LRRC58 | 0.787953 | 3 | 0 | 3 |
| MED26 | KANSL2 | 0.784799 | 3 | 0 | 3 |
| MED26 | LYRM4 | 0.782612 | 3 | 0 | 3 |
| MED26 | COQ4 | 0.778772 | 3 | 0 | 3 |
| MED26 | SH2B1 | 0.777359 | 3 | 0 | 3 |
| MED26 | TRIT1 | 0.777106 | 3 | 0 | 3 |
| MED26 | CHD4 | 0.774682 | 3 | 0 | 3 |
| MED26 | NACC1 | 0.76649 | 3 | 0 | 3 |
| MED26 | PAPOLG | 0.763509 | 3 | 0 | 3 |
| MED26 | EP400 | 0.763119 | 3 | 0 | 3 |
| MED26 | POLA1 | 0.762432 | 3 | 0 | 3 |
| MED26 | MLLT1 | 0.758169 | 4 | 0 | 4 |
| MED26 | MCOLN1 | 0.754271 | 3 | 0 | 3 |
| MED26 | ATG3 | 0.753552 | 3 | 0 | 3 |
| MED26 | ZFYVE27 | 0.752087 | 3 | 0 | 3 |
| MED26 | MRPS15 | 0.751831 | 3 | 0 | 3 |
| MED26 | PPP2R3C | 0.749932 | 3 | 0 | 3 |
For details and further investigation, click here
