MRGPRX1

 

Full name: MAS related GPR family member X1 Alias Symbol: MRGX1
Type: protein-coding gene Cytoband: 11p15.1
Entrez ID: 259249 HGNC ID: HGNC:17962 Ensembl Gene: ENSG00000170255 OMIM ID: 607227
Related drugs: CHLOROQUINE... [more]

 

Expression of MRGPRX1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MRGPRX1 259249 1553401_at 0.1410 0.5301
GSE26886 MRGPRX1 259249 1553401_at 0.0668 0.4177
GSE45670 MRGPRX1 259249 1553401_at 0.1992 0.0053
GSE53622 MRGPRX1 259249 68747 0.3281 0.0376
GSE53624 MRGPRX1 259249 68747 0.1476 0.1449
GSE63941 MRGPRX1 259249 1553401_at -0.1938 0.1918
GSE77861 MRGPRX1 259249 1553401_at -0.0370 0.7350

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MRGPRX1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MRGPRX1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MRGPRX1 259249 0 10 20
GSE20123 MRGPRX1 259249 0 10 20
GSE43470 MRGPRX1 259249 1 5 37
GSE46452 MRGPRX1 259249 7 5 47
GSE47630 MRGPRX1 259249 3 10 27
GSE54993 MRGPRX1 259249 3 0 67
GSE54994 MRGPRX1 259249 3 12 38
GSE60625 MRGPRX1 259249 0 0 11
GSE74703 MRGPRX1 259249 1 3 32
GSE74704 MRGPRX1 259249 0 9 11
TCGA MRGPRX1 259249 12 28 56

Total number of gains: 30; Total number of losses: 92; Total Number of normals: 366.  


 

Somatic mutations of MRGPRX1:

 

Generating mutation plots.

 

Highly correlated genes for MRGPRX1:

 

Showing all 15 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MRGPRX1S100A7A0.673763303
MRGPRX1GPR680.606396403
MRGPRX1CATSPERB0.594606303
MRGPRX1PTPN20.590297303
MRGPRX1HAPLN10.590003404
MRGPRX1RBM450.583692303
MRGPRX1IFI160.58254303
MRGPRX1CPNE80.562144303
MRGPRX1NFYA0.556444303
MRGPRX1UBA60.550425403
MRGPRX1C90.543368403
MRGPRX1BTF3L40.53079403
MRGPRX1EXT10.530158403
MRGPRX1HK20.529533303
MRGPRX1MCHR10.510903303

For details and further investigation, click here