NFYA

 

Full name: nuclear transcription factor Y subunit alpha Alias Symbol: HAP2|CBF-B|NF-YA
Type: protein-coding gene Cytoband: 6p21.1
Entrez ID: 4800 HGNC ID: HGNC:7804 Ensembl Gene: ENSG00000001167 OMIM ID: 189903
Drug and gene relationship at DGIdb
Screen Evidence:

 

NFYA involved pathways:

KEGG pathway Description View
hsa04612Antigen processing and presentation
hsa05152Tuberculosis

 

Expression of NFYA:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NFYA 4800 204108_at 1.1631 0.0647
GSE20347 NFYA 4800 204108_at 0.6115 0.0006
GSE23400 NFYA 4800 204108_at 0.4725 0.0000
GSE26886 NFYA 4800 204108_at -0.5968 0.0410
GSE29001 NFYA 4800 204108_at 0.5575 0.0701
GSE38129 NFYA 4800 204108_at 0.6414 0.0000
GSE45670 NFYA 4800 204108_at 0.7417 0.0000
GSE53622 NFYA 4800 12477 0.5855 0.0000
GSE53624 NFYA 4800 12477 0.8847 0.0000
GSE63941 NFYA 4800 204108_at -0.5304 0.0890
GSE77861 NFYA 4800 215720_s_at -0.0486 0.7819
GSE97050 NFYA 4800 A_24_P414719 -0.2798 0.4683
SRP007169 NFYA 4800 RNAseq -0.0264 0.9436
SRP008496 NFYA 4800 RNAseq 0.2887 0.2774
SRP064894 NFYA 4800 RNAseq 0.4541 0.0453
SRP133303 NFYA 4800 RNAseq 0.4612 0.0015
SRP159526 NFYA 4800 RNAseq 0.3190 0.1491
SRP193095 NFYA 4800 RNAseq 0.0764 0.4850
SRP219564 NFYA 4800 RNAseq 0.3834 0.3036
TCGA NFYA 4800 RNAseq -0.0068 0.8948

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by NFYA expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NFYA:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NFYA 4800 3 3 24
GSE20123 NFYA 4800 3 3 24
GSE43470 NFYA 4800 6 0 37
GSE46452 NFYA 4800 2 9 48
GSE47630 NFYA 4800 8 4 28
GSE54993 NFYA 4800 3 2 65
GSE54994 NFYA 4800 11 4 38
GSE60625 NFYA 4800 0 1 10
GSE74703 NFYA 4800 6 0 30
GSE74704 NFYA 4800 1 3 16
TCGA NFYA 4800 19 13 64

Total number of gains: 62; Total number of losses: 42; Total Number of normals: 384.  

 

Somatic mutations of NFYA:

 

Generating mutation plots.

 

Highly correlated genes for NFYA:

 

Showing top 20/158 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NFYALAT0.773194303
NFYAANKLE10.718457303
NFYAZNF4440.711469303
NFYAGPC20.68101404
NFYARAD54B0.672548908
NFYAECT20.669187707
NFYACDCA50.658471505
NFYAGPR1800.656871503
NFYAMED200.6563961008
NFYAMTERF30.652121605
NFYATUBB0.647935808
NFYAMEX3D0.646018605
NFYASERPINH10.644305807
NFYASCN9A0.64374303
NFYAING50.642322403
NFYACKS20.640903706
NFYASPDL10.639743707
NFYABAX0.633587605
NFYAMEST0.631749807
NFYAZDHHC80.63128503

For details and further investigation, click here