| Full name: S100 calcium binding protein A7A | Alias Symbol: S100A7f | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 338324 | HGNC ID: HGNC:21657 | Ensembl Gene: ENSG00000184330 | OMIM ID: 617427 |
| Drug and gene relationship at DGIdb | |||
Expression of S100A7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | S100A7A | 338324 | 232170_at | 2.6136 | 0.2148 | |
| GSE26886 | S100A7A | 338324 | 232220_at | 0.1013 | 0.5083 | |
| GSE45670 | S100A7A | 338324 | 232170_at | 4.9066 | 0.0000 | |
| GSE53622 | S100A7A | 338324 | 13783 | 3.1460 | 0.0000 | |
| GSE53624 | S100A7A | 338324 | 13783 | 2.5471 | 0.0000 | |
| GSE63941 | S100A7A | 338324 | 232220_at | -0.0422 | 0.8484 | |
| GSE77861 | S100A7A | 338324 | 232220_at | -0.0994 | 0.6001 | |
| SRP133303 | S100A7A | 338324 | RNAseq | 2.7160 | 0.0429 | |
| TCGA | S100A7A | 338324 | RNAseq | 3.6375 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by S100A7A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of S100A7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | S100A7A | 338324 | 14 | 0 | 16 | |
| GSE20123 | S100A7A | 338324 | 14 | 0 | 16 | |
| GSE43470 | S100A7A | 338324 | 6 | 2 | 35 | |
| GSE46452 | S100A7A | 338324 | 2 | 1 | 56 | |
| GSE47630 | S100A7A | 338324 | 15 | 0 | 25 | |
| GSE54993 | S100A7A | 338324 | 0 | 4 | 66 | |
| GSE54994 | S100A7A | 338324 | 16 | 0 | 37 | |
| GSE60625 | S100A7A | 338324 | 0 | 0 | 11 | |
| GSE74703 | S100A7A | 338324 | 6 | 1 | 29 | |
| GSE74704 | S100A7A | 338324 | 7 | 0 | 13 | |
| TCGA | S100A7A | 338324 | 40 | 2 | 54 |
Total number of gains: 120; Total number of losses: 10; Total Number of normals: 358.
Somatic mutations of S100A7A:
Generating mutation plots.
Highly correlated genes for S100A7A:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| S100A7A | S100A7 | 0.79782 | 5 | 0 | 5 |
| S100A7A | IL36G | 0.752184 | 4 | 0 | 4 |
| S100A7A | ADAMTS14 | 0.716995 | 3 | 0 | 3 |
| S100A7A | CDH3 | 0.716847 | 3 | 0 | 3 |
| S100A7A | MMP1 | 0.688696 | 4 | 0 | 3 |
| S100A7A | MPHOSPH6 | 0.681124 | 4 | 0 | 3 |
| S100A7A | MMP12 | 0.678821 | 4 | 0 | 4 |
| S100A7A | SIL1 | 0.678659 | 3 | 0 | 3 |
| S100A7A | PLA2G4E | 0.674337 | 3 | 0 | 3 |
| S100A7A | MRGPRX1 | 0.673763 | 3 | 0 | 3 |
| S100A7A | WDR66 | 0.67292 | 4 | 0 | 3 |
| S100A7A | LINC01137 | 0.663039 | 4 | 0 | 4 |
| S100A7A | ABCA12 | 0.662754 | 5 | 0 | 4 |
| S100A7A | SYT4 | 0.661434 | 3 | 0 | 3 |
| S100A7A | FAM207A | 0.65899 | 3 | 0 | 3 |
| S100A7A | DERL1 | 0.655697 | 3 | 0 | 3 |
| S100A7A | PDZK1IP1 | 0.65198 | 3 | 0 | 3 |
| S100A7A | CXCL1 | 0.651586 | 4 | 0 | 4 |
| S100A7A | TMEM45A | 0.64603 | 6 | 0 | 4 |
| S100A7A | FSCN1 | 0.638257 | 4 | 0 | 3 |
For details and further investigation, click here
