| Full name: melanin concentrating hormone receptor 1 | Alias Symbol: SLC1|MCH1R | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 2847 | HGNC ID: HGNC:4479 | Ensembl Gene: ENSG00000128285 | OMIM ID: 601751 |
| Drug and gene relationship at DGIdb | |||
Expression of MCHR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCHR1 | 2847 | 223855_s_at | 0.1403 | 0.4454 | |
| GSE20347 | MCHR1 | 2847 | 221354_s_at | -0.1979 | 0.0053 | |
| GSE23400 | MCHR1 | 2847 | 221354_s_at | -0.2498 | 0.0000 | |
| GSE26886 | MCHR1 | 2847 | 230498_at | 0.1405 | 0.4729 | |
| GSE29001 | MCHR1 | 2847 | 221354_s_at | -0.3166 | 0.0886 | |
| GSE38129 | MCHR1 | 2847 | 221354_s_at | -0.1678 | 0.0800 | |
| GSE45670 | MCHR1 | 2847 | 223855_s_at | 0.0381 | 0.6548 | |
| GSE53622 | MCHR1 | 2847 | 6566 | 0.7691 | 0.0000 | |
| GSE53624 | MCHR1 | 2847 | 6566 | 0.5643 | 0.0000 | |
| GSE63941 | MCHR1 | 2847 | 230498_at | -0.5524 | 0.0013 | |
| GSE77861 | MCHR1 | 2847 | 230498_at | -0.1423 | 0.2919 | |
| GSE97050 | MCHR1 | 2847 | A_33_P3393311 | -0.0271 | 0.9381 | |
| TCGA | MCHR1 | 2847 | RNAseq | 0.7514 | 0.1086 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MCHR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MCHR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MCHR1 | 2847 | 6 | 5 | 19 | |
| GSE20123 | MCHR1 | 2847 | 6 | 4 | 20 | |
| GSE43470 | MCHR1 | 2847 | 4 | 6 | 33 | |
| GSE46452 | MCHR1 | 2847 | 31 | 2 | 26 | |
| GSE47630 | MCHR1 | 2847 | 9 | 4 | 27 | |
| GSE54993 | MCHR1 | 2847 | 3 | 6 | 61 | |
| GSE54994 | MCHR1 | 2847 | 11 | 7 | 35 | |
| GSE60625 | MCHR1 | 2847 | 5 | 0 | 6 | |
| GSE74703 | MCHR1 | 2847 | 4 | 4 | 28 | |
| GSE74704 | MCHR1 | 2847 | 3 | 2 | 15 | |
| TCGA | MCHR1 | 2847 | 26 | 15 | 55 |
Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.
Somatic mutations of MCHR1:
Generating mutation plots.
Highly correlated genes for MCHR1:
Showing top 20/472 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCHR1 | PSPN | 0.707894 | 4 | 0 | 4 |
| MCHR1 | OR2S2 | 0.693297 | 3 | 0 | 3 |
| MCHR1 | FGF23 | 0.684665 | 4 | 0 | 4 |
| MCHR1 | TAS2R1 | 0.684254 | 3 | 0 | 3 |
| MCHR1 | NPAP1 | 0.680502 | 5 | 0 | 5 |
| MCHR1 | PF4 | 0.680396 | 4 | 0 | 4 |
| MCHR1 | CHRM2 | 0.679405 | 5 | 0 | 5 |
| MCHR1 | PRKACG | 0.672774 | 5 | 0 | 5 |
| MCHR1 | RBFADN | 0.671533 | 4 | 0 | 3 |
| MCHR1 | IL18BP | 0.668239 | 6 | 0 | 5 |
| MCHR1 | EFR3B | 0.667649 | 4 | 0 | 4 |
| MCHR1 | HMHB1 | 0.666247 | 3 | 0 | 3 |
| MCHR1 | KRT76 | 0.664295 | 4 | 0 | 3 |
| MCHR1 | ADRA1D | 0.661767 | 5 | 0 | 5 |
| MCHR1 | ACRV1 | 0.661156 | 4 | 0 | 4 |
| MCHR1 | DEFA5 | 0.660572 | 4 | 0 | 4 |
| MCHR1 | IL2RA | 0.660391 | 3 | 0 | 3 |
| MCHR1 | PRL | 0.659877 | 5 | 0 | 5 |
| MCHR1 | NECAP2 | 0.658035 | 3 | 0 | 3 |
| MCHR1 | ATG10 | 0.656301 | 4 | 0 | 3 |
For details and further investigation, click here
