| Full name: hyaluronan and proteoglycan link protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q14.3 | ||
| Entrez ID: 1404 | HGNC ID: HGNC:2380 | Ensembl Gene: ENSG00000145681 | OMIM ID: 115435 |
| Drug and gene relationship at DGIdb | |||
Expression of HAPLN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAPLN1 | 1404 | 205524_s_at | 0.3207 | 0.5655 | |
| GSE20347 | HAPLN1 | 1404 | 205524_s_at | 0.0619 | 0.5160 | |
| GSE23400 | HAPLN1 | 1404 | 205524_s_at | -0.1647 | 0.0008 | |
| GSE26886 | HAPLN1 | 1404 | 205524_s_at | -0.0481 | 0.7387 | |
| GSE29001 | HAPLN1 | 1404 | 205524_s_at | 0.0216 | 0.9104 | |
| GSE38129 | HAPLN1 | 1404 | 205524_s_at | 0.0051 | 0.9756 | |
| GSE45670 | HAPLN1 | 1404 | 205524_s_at | 0.2924 | 0.0295 | |
| GSE53622 | HAPLN1 | 1404 | 151610 | -0.2198 | 0.4766 | |
| GSE53624 | HAPLN1 | 1404 | 151610 | 0.3650 | 0.1949 | |
| GSE63941 | HAPLN1 | 1404 | 205524_s_at | -0.1829 | 0.4317 | |
| GSE77861 | HAPLN1 | 1404 | 205524_s_at | -0.0514 | 0.7252 | |
| SRP133303 | HAPLN1 | 1404 | RNAseq | 0.6815 | 0.0865 | |
| SRP159526 | HAPLN1 | 1404 | RNAseq | 0.3144 | 0.6299 | |
| SRP219564 | HAPLN1 | 1404 | RNAseq | -0.2634 | 0.7782 | |
| TCGA | HAPLN1 | 1404 | RNAseq | -0.5173 | 0.0927 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HAPLN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAPLN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAPLN1 | 1404 | 1 | 14 | 15 | |
| GSE20123 | HAPLN1 | 1404 | 1 | 14 | 15 | |
| GSE43470 | HAPLN1 | 1404 | 2 | 10 | 31 | |
| GSE46452 | HAPLN1 | 1404 | 0 | 28 | 31 | |
| GSE47630 | HAPLN1 | 1404 | 1 | 19 | 20 | |
| GSE54993 | HAPLN1 | 1404 | 8 | 1 | 61 | |
| GSE54994 | HAPLN1 | 1404 | 1 | 18 | 34 | |
| GSE60625 | HAPLN1 | 1404 | 0 | 0 | 11 | |
| GSE74703 | HAPLN1 | 1404 | 1 | 7 | 28 | |
| GSE74704 | HAPLN1 | 1404 | 1 | 7 | 12 | |
| TCGA | HAPLN1 | 1404 | 3 | 48 | 45 |
Total number of gains: 19; Total number of losses: 166; Total Number of normals: 303.
Somatic mutations of HAPLN1:
Generating mutation plots.
Highly correlated genes for HAPLN1:
Showing top 20/163 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAPLN1 | SCGN | 0.758267 | 3 | 0 | 3 |
| HAPLN1 | ZMAT4 | 0.755216 | 3 | 0 | 3 |
| HAPLN1 | AQP2 | 0.714764 | 3 | 0 | 3 |
| HAPLN1 | SPATA9 | 0.690599 | 3 | 0 | 3 |
| HAPLN1 | NCR2 | 0.676298 | 3 | 0 | 3 |
| HAPLN1 | OXT | 0.675168 | 3 | 0 | 3 |
| HAPLN1 | SSTR1 | 0.6718 | 4 | 0 | 3 |
| HAPLN1 | MAGEA8 | 0.668006 | 3 | 0 | 3 |
| HAPLN1 | GUCY1A2 | 0.666709 | 5 | 0 | 4 |
| HAPLN1 | CACNG1 | 0.657525 | 3 | 0 | 3 |
| HAPLN1 | TRHDE | 0.657497 | 3 | 0 | 3 |
| HAPLN1 | MGAT4C | 0.647274 | 3 | 0 | 3 |
| HAPLN1 | C16orf87 | 0.646233 | 3 | 0 | 3 |
| HAPLN1 | AHR | 0.646078 | 3 | 0 | 3 |
| HAPLN1 | TRPC7 | 0.646035 | 3 | 0 | 3 |
| HAPLN1 | KRT38 | 0.645749 | 3 | 0 | 3 |
| HAPLN1 | MMP16 | 0.645584 | 4 | 0 | 3 |
| HAPLN1 | SLC5A4 | 0.645577 | 4 | 0 | 3 |
| HAPLN1 | SMIM2 | 0.645021 | 3 | 0 | 3 |
| HAPLN1 | RPH3A | 0.644038 | 3 | 0 | 3 |
For details and further investigation, click here
