PHEX

 

Full name: phosphate regulating endopeptidase homolog X-linked Alias Symbol: PEX|HPDR1|HYP1|XLH
Type: protein-coding gene Cytoband: Xp22.11
Entrez ID: 5251 HGNC ID: HGNC:8918 Ensembl Gene: ENSG00000102174 OMIM ID: 300550
Drug and gene relationship at DGIdb

 

Expression of PHEX:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PHEX 5251 210617_at -0.2082 0.6078
GSE20347 PHEX 5251 210617_at -0.1724 0.0051
GSE23400 PHEX 5251 210617_at -0.0942 0.0063
GSE26886 PHEX 5251 239229_at 0.7464 0.0195
GSE29001 PHEX 5251 210617_at -0.0887 0.5721
GSE38129 PHEX 5251 210617_at -0.0845 0.3709
GSE45670 PHEX 5251 210617_at 0.0560 0.6546
GSE53622 PHEX 5251 66060 0.3405 0.0391
GSE53624 PHEX 5251 66060 0.6367 0.0000
GSE63941 PHEX 5251 210617_at 0.6558 0.1118
GSE77861 PHEX 5251 210617_at -0.0255 0.8565
GSE97050 PHEX 5251 A_23_P114084 -0.0685 0.8438
SRP064894 PHEX 5251 RNAseq 1.3193 0.0002
SRP133303 PHEX 5251 RNAseq 1.3404 0.0003
SRP159526 PHEX 5251 RNAseq 0.9738 0.0947
SRP219564 PHEX 5251 RNAseq 1.1495 0.1265
TCGA PHEX 5251 RNAseq 1.2198 0.0046

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by PHEX expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PHEX:

 

No record found for this gene.


 

Somatic mutations of PHEX:

 

Generating mutation plots.

 

Highly correlated genes for PHEX:

 

Showing top 20/613 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PHEXPRAMEF120.724807303
PHEXCSPG50.702781303
PHEXIL9R0.699744303
PHEXCTNNA20.696413303
PHEXNXPH30.694437404
PHEXGIP0.692728303
PHEXSLC17A30.685867303
PHEXOR2H20.685125505
PHEXMTTP0.683251303
PHEXCAPN110.682175303
PHEXZCCHC120.680927303
PHEXGPR1460.679058303
PHEXSCGN0.676789404
PHEXMPP20.67546606
PHEXRSPH6A0.674189505
PHEXGPR880.674008303
PHEXHRC0.673409505
PHEXAGAP20.668595404
PHEXHAO20.664878303
PHEXTHPO0.664875606

For details and further investigation, click here