| Full name: fructose-bisphosphatase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q22.32 | ||
| Entrez ID: 8789 | HGNC ID: HGNC:3607 | Ensembl Gene: ENSG00000130957 | OMIM ID: 603027 |
FBP2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04152 | AMPK signaling pathway | |
| hsa04910 | Insulin signaling pathway |
Expression of FBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBP2 | 8789 | 206844_at | -0.0963 | 0.7103 | |
| GSE20347 | FBP2 | 8789 | 206844_at | -0.0481 | 0.5415 | |
| GSE23400 | FBP2 | 8789 | 206844_at | -0.1933 | 0.0001 | |
| GSE26886 | FBP2 | 8789 | 206844_at | -0.0257 | 0.8330 | |
| GSE29001 | FBP2 | 8789 | 206844_at | -0.0983 | 0.3761 | |
| GSE38129 | FBP2 | 8789 | 206844_at | -0.3318 | 0.0483 | |
| GSE45670 | FBP2 | 8789 | 206844_at | -0.0222 | 0.8182 | |
| GSE63941 | FBP2 | 8789 | 206844_at | 0.1947 | 0.2123 | |
| GSE77861 | FBP2 | 8789 | 206844_at | -0.0585 | 0.4905 | |
| TCGA | FBP2 | 8789 | RNAseq | -4.9077 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FBP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBP2 | 8789 | 5 | 9 | 16 | |
| GSE20123 | FBP2 | 8789 | 5 | 9 | 16 | |
| GSE43470 | FBP2 | 8789 | 6 | 3 | 34 | |
| GSE46452 | FBP2 | 8789 | 6 | 14 | 39 | |
| GSE47630 | FBP2 | 8789 | 1 | 17 | 22 | |
| GSE54993 | FBP2 | 8789 | 4 | 2 | 64 | |
| GSE54994 | FBP2 | 8789 | 8 | 11 | 34 | |
| GSE60625 | FBP2 | 8789 | 0 | 0 | 11 | |
| GSE74703 | FBP2 | 8789 | 5 | 3 | 28 | |
| GSE74704 | FBP2 | 8789 | 2 | 7 | 11 | |
| TCGA | FBP2 | 8789 | 24 | 23 | 49 |
Total number of gains: 66; Total number of losses: 98; Total Number of normals: 324.
Somatic mutations of FBP2:
Generating mutation plots.
Highly correlated genes for FBP2:
Showing top 20/825 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBP2 | IFNA10 | 0.756543 | 4 | 0 | 4 |
| FBP2 | CRHR2 | 0.738507 | 4 | 0 | 4 |
| FBP2 | GNMT | 0.722161 | 3 | 0 | 3 |
| FBP2 | CAPN11 | 0.715627 | 4 | 0 | 4 |
| FBP2 | CPS1-IT1 | 0.70993 | 4 | 0 | 3 |
| FBP2 | CAMP | 0.697335 | 3 | 0 | 3 |
| FBP2 | LCN15 | 0.694702 | 3 | 0 | 3 |
| FBP2 | SIGLEC8 | 0.693395 | 3 | 0 | 3 |
| FBP2 | MTTP | 0.685275 | 3 | 0 | 3 |
| FBP2 | TM4SF4 | 0.682518 | 5 | 0 | 4 |
| FBP2 | MATN1 | 0.681703 | 3 | 0 | 3 |
| FBP2 | ZNF460 | 0.680334 | 3 | 0 | 3 |
| FBP2 | NTNG1 | 0.677109 | 3 | 0 | 3 |
| FBP2 | LUZP4 | 0.675217 | 4 | 0 | 4 |
| FBP2 | LGI2 | 0.667622 | 3 | 0 | 3 |
| FBP2 | EDA2R | 0.665361 | 5 | 0 | 5 |
| FBP2 | AIRE | 0.664305 | 4 | 0 | 4 |
| FBP2 | IRS4 | 0.663692 | 4 | 0 | 4 |
| FBP2 | CCKAR | 0.662562 | 5 | 0 | 4 |
| FBP2 | ANGPTL3 | 0.662275 | 4 | 0 | 4 |
For details and further investigation, click here
