MUC12

 

Full name: mucin 12, cell surface associated Alias Symbol: 
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 10071 HGNC ID: HGNC:7510 Ensembl Gene: ENSG00000205277 OMIM ID: 604609
Drug and gene relationship at DGIdb

 

Expression of MUC12:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MUC12 10071 226654_at 0.0281 0.9163
GSE26886 MUC12 10071 226654_at 0.2737 0.0187
GSE45670 MUC12 10071 226654_at 0.1842 0.0167
GSE53622 MUC12 10071 98283 0.8970 0.0000
GSE53624 MUC12 10071 98283 0.6841 0.0000
GSE63941 MUC12 10071 226654_at 0.1080 0.6541
GSE77861 MUC12 10071 226654_at -0.1279 0.2702
GSE97050 MUC12 10071 A_24_P658413 0.0470 0.8608
SRP133303 MUC12 10071 RNAseq 0.9524 0.0274
TCGA MUC12 10071 RNAseq 0.0497 0.8994

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MUC12 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MUC12:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MUC12 10071 13 0 17
GSE20123 MUC12 10071 13 0 17
GSE43470 MUC12 10071 7 2 34
GSE46452 MUC12 10071 11 1 47
GSE47630 MUC12 10071 7 3 30
GSE54993 MUC12 10071 1 10 59
GSE54994 MUC12 10071 15 3 35
GSE60625 MUC12 10071 0 0 11
GSE74703 MUC12 10071 7 1 28
GSE74704 MUC12 10071 9 0 11
TCGA MUC12 10071 53 6 37

Total number of gains: 136; Total number of losses: 26; Total Number of normals: 326.  


 

Somatic mutations of MUC12:

 

Generating mutation plots.

 

Highly correlated genes for MUC12:

 

Showing top 20/107 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MUC12COX6A20.695564303
MUC12KRTAP5-70.694493303
MUC12KRTAP10-120.691975303
MUC12LINC012810.679429303
MUC12F2RL30.654803303
MUC12FAM222A-AS10.653195303
MUC12IGFL30.646297303
MUC12PIPOX0.642874303
MUC12FBXO170.642729303
MUC12EPB420.641585303
MUC12KRT730.637632404
MUC12OR5H10.636532404
MUC12NTNG20.6278303
MUC12KCNK90.625776403
MUC12DNAI10.62508303
MUC12PRSS500.624048403
MUC12DENND30.62094303
MUC12PDGFB0.619438303
MUC12FFAR10.612839403
MUC12PDZD70.605629403

For details and further investigation, click here