| Full name: PDZ domain containing 7 | Alias Symbol: FLJ23209|bA108L7.8 | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 79955 | HGNC ID: HGNC:26257 | Ensembl Gene: ENSG00000186862 | OMIM ID: 612971 |
| Drug and gene relationship at DGIdb | |||
Expression of PDZD7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDZD7 | 79955 | 220555_s_at | -0.0768 | 0.6971 | |
| GSE20347 | PDZD7 | 79955 | 220555_s_at | -0.0511 | 0.5741 | |
| GSE23400 | PDZD7 | 79955 | 220555_s_at | -0.1852 | 0.0000 | |
| GSE26886 | PDZD7 | 79955 | 220555_s_at | 0.1828 | 0.1796 | |
| GSE29001 | PDZD7 | 79955 | 220555_s_at | -0.1635 | 0.2934 | |
| GSE38129 | PDZD7 | 79955 | 220555_s_at | -0.1086 | 0.0698 | |
| GSE45670 | PDZD7 | 79955 | 220555_s_at | 0.0539 | 0.5897 | |
| GSE53622 | PDZD7 | 79955 | 137217 | 0.4883 | 0.0002 | |
| GSE53624 | PDZD7 | 79955 | 137217 | 0.4604 | 0.0002 | |
| GSE63941 | PDZD7 | 79955 | 220555_s_at | 0.3248 | 0.0552 | |
| GSE77861 | PDZD7 | 79955 | 220555_s_at | -0.2473 | 0.0792 | |
| GSE97050 | PDZD7 | 79955 | A_33_P3286916 | 0.3831 | 0.2587 | |
| SRP064894 | PDZD7 | 79955 | RNAseq | 0.9061 | 0.0000 | |
| SRP133303 | PDZD7 | 79955 | RNAseq | 0.3394 | 0.0105 | |
| SRP159526 | PDZD7 | 79955 | RNAseq | 1.0255 | 0.0726 | |
| SRP193095 | PDZD7 | 79955 | RNAseq | 0.2091 | 0.1740 | |
| SRP219564 | PDZD7 | 79955 | RNAseq | 0.8572 | 0.0310 | |
| TCGA | PDZD7 | 79955 | RNAseq | 0.3807 | 0.4312 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDZD7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDZD7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDZD7 | 79955 | 1 | 8 | 21 | |
| GSE20123 | PDZD7 | 79955 | 1 | 7 | 22 | |
| GSE43470 | PDZD7 | 79955 | 0 | 8 | 35 | |
| GSE46452 | PDZD7 | 79955 | 0 | 11 | 48 | |
| GSE47630 | PDZD7 | 79955 | 2 | 14 | 24 | |
| GSE54993 | PDZD7 | 79955 | 8 | 0 | 62 | |
| GSE54994 | PDZD7 | 79955 | 1 | 12 | 40 | |
| GSE60625 | PDZD7 | 79955 | 0 | 0 | 11 | |
| GSE74703 | PDZD7 | 79955 | 0 | 5 | 31 | |
| GSE74704 | PDZD7 | 79955 | 0 | 4 | 16 | |
| TCGA | PDZD7 | 79955 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of PDZD7:
Generating mutation plots.
Highly correlated genes for PDZD7:
Showing top 20/857 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDZD7 | STRC | 0.816676 | 3 | 0 | 3 |
| PDZD7 | MFSD6L | 0.785154 | 3 | 0 | 3 |
| PDZD7 | LHB | 0.779946 | 3 | 0 | 3 |
| PDZD7 | PTPRN2 | 0.774473 | 6 | 0 | 6 |
| PDZD7 | ELOVL3 | 0.772796 | 3 | 0 | 3 |
| PDZD7 | DEFB128 | 0.755754 | 3 | 0 | 3 |
| PDZD7 | GLI4 | 0.753848 | 3 | 0 | 3 |
| PDZD7 | NTNG2 | 0.752252 | 3 | 0 | 3 |
| PDZD7 | LRRC10 | 0.750459 | 3 | 0 | 3 |
| PDZD7 | PLA2G2C | 0.744485 | 3 | 0 | 3 |
| PDZD7 | C9orf153 | 0.744308 | 3 | 0 | 3 |
| PDZD7 | C8orf74 | 0.743148 | 4 | 0 | 4 |
| PDZD7 | DCDC1 | 0.743082 | 3 | 0 | 3 |
| PDZD7 | KRTAP10-12 | 0.737722 | 3 | 0 | 3 |
| PDZD7 | C2orf81 | 0.73719 | 3 | 0 | 3 |
| PDZD7 | OR2A5 | 0.736916 | 3 | 0 | 3 |
| PDZD7 | ASTL | 0.726566 | 3 | 0 | 3 |
| PDZD7 | ZNF527 | 0.721514 | 3 | 0 | 3 |
| PDZD7 | PRAMEF5 | 0.721246 | 3 | 0 | 3 |
| PDZD7 | OR2T27 | 0.716924 | 3 | 0 | 3 |
For details and further investigation, click here
