| Full name: IGF like family member 3 | Alias Symbol: UNQ483 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 388555 | HGNC ID: HGNC:32930 | Ensembl Gene: ENSG00000188624 | OMIM ID: 610546 |
| Drug and gene relationship at DGIdb | |||
Expression of IGFL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | IGFL3 | 388555 | 36739 | 1.1176 | 0.0000 | |
| GSE53624 | IGFL3 | 388555 | 36739 | 1.8456 | 0.0000 | |
| GSE97050 | IGFL3 | 388555 | A_33_P3243454 | -0.0075 | 0.9777 | |
| SRP133303 | IGFL3 | 388555 | RNAseq | 0.6893 | 0.1198 | |
| TCGA | IGFL3 | 388555 | RNAseq | 5.9213 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by IGFL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGFL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGFL3 | 388555 | 4 | 5 | 21 | |
| GSE20123 | IGFL3 | 388555 | 4 | 4 | 22 | |
| GSE43470 | IGFL3 | 388555 | 3 | 11 | 29 | |
| GSE46452 | IGFL3 | 388555 | 45 | 1 | 13 | |
| GSE47630 | IGFL3 | 388555 | 8 | 7 | 25 | |
| GSE54993 | IGFL3 | 388555 | 17 | 4 | 49 | |
| GSE54994 | IGFL3 | 388555 | 4 | 14 | 35 | |
| GSE60625 | IGFL3 | 388555 | 9 | 0 | 2 | |
| GSE74703 | IGFL3 | 388555 | 3 | 7 | 26 | |
| GSE74704 | IGFL3 | 388555 | 4 | 2 | 14 | |
| TCGA | IGFL3 | 388555 | 15 | 15 | 66 |
Total number of gains: 116; Total number of losses: 70; Total Number of normals: 302.
Somatic mutations of IGFL3:
Generating mutation plots.
Highly correlated genes for IGFL3:
Showing all 18 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGFL3 | GRIP2 | 0.723448 | 3 | 0 | 3 |
| IGFL3 | USP17L2 | 0.70022 | 3 | 0 | 3 |
| IGFL3 | TG | 0.688187 | 3 | 0 | 3 |
| IGFL3 | PLOD3 | 0.664993 | 3 | 0 | 3 |
| IGFL3 | ZNF445 | 0.655346 | 3 | 0 | 3 |
| IGFL3 | MUC12 | 0.646297 | 3 | 0 | 3 |
| IGFL3 | FAM111B | 0.644392 | 3 | 0 | 3 |
| IGFL3 | ALG11 | 0.639865 | 3 | 0 | 3 |
| IGFL3 | REV3L | 0.631844 | 3 | 0 | 3 |
| IGFL3 | SZT2 | 0.620387 | 3 | 0 | 3 |
| IGFL3 | PDGFB | 0.611787 | 3 | 0 | 3 |
| IGFL3 | NRSN2 | 0.611536 | 3 | 0 | 3 |
| IGFL3 | PRR23C | 0.594677 | 3 | 0 | 3 |
| IGFL3 | ASB3 | 0.582089 | 3 | 0 | 3 |
| IGFL3 | SYNGR3 | 0.578438 | 3 | 0 | 3 |
| IGFL3 | STK3 | 0.539807 | 3 | 0 | 3 |
| IGFL3 | CORO6 | 0.539332 | 3 | 0 | 3 |
| IGFL3 | SMAD2 | 0.527252 | 4 | 0 | 3 |
For details and further investigation, click here
