| Full name: erythrocyte membrane protein band 4.2 | Alias Symbol: PA|MGC116735|MGC116737 | ||
| Type: protein-coding gene | Cytoband: 15q15.2 | ||
| Entrez ID: 2038 | HGNC ID: HGNC:3381 | Ensembl Gene: ENSG00000166947 | OMIM ID: 177070 |
| Drug and gene relationship at DGIdb | |||
Expression of EPB42:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPB42 | 2038 | 210746_s_at | -0.3542 | 0.1852 | |
| GSE20347 | EPB42 | 2038 | 210746_s_at | -0.1446 | 0.1139 | |
| GSE23400 | EPB42 | 2038 | 210746_s_at | -0.1623 | 0.0000 | |
| GSE26886 | EPB42 | 2038 | 210746_s_at | -0.0092 | 0.9473 | |
| GSE29001 | EPB42 | 2038 | 210746_s_at | -0.3713 | 0.0169 | |
| GSE38129 | EPB42 | 2038 | 210746_s_at | -0.2089 | 0.0134 | |
| GSE45670 | EPB42 | 2038 | 210746_s_at | -0.0805 | 0.4640 | |
| GSE53622 | EPB42 | 2038 | 45323 | 0.1994 | 0.0945 | |
| GSE53624 | EPB42 | 2038 | 45323 | 0.1076 | 0.3312 | |
| GSE63941 | EPB42 | 2038 | 210746_s_at | 0.1513 | 0.3294 | |
| GSE77861 | EPB42 | 2038 | 210746_s_at | -0.2160 | 0.0406 | |
| GSE97050 | EPB42 | 2038 | A_23_P140675 | 0.0863 | 0.7130 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EPB42 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPB42:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPB42 | 2038 | 4 | 5 | 21 | |
| GSE20123 | EPB42 | 2038 | 4 | 6 | 20 | |
| GSE43470 | EPB42 | 2038 | 3 | 5 | 35 | |
| GSE46452 | EPB42 | 2038 | 3 | 7 | 49 | |
| GSE47630 | EPB42 | 2038 | 8 | 10 | 22 | |
| GSE54993 | EPB42 | 2038 | 4 | 6 | 60 | |
| GSE54994 | EPB42 | 2038 | 5 | 7 | 41 | |
| GSE60625 | EPB42 | 2038 | 4 | 0 | 7 | |
| GSE74703 | EPB42 | 2038 | 3 | 3 | 30 | |
| GSE74704 | EPB42 | 2038 | 3 | 3 | 14 | |
| TCGA | EPB42 | 2038 | 12 | 17 | 67 |
Total number of gains: 53; Total number of losses: 69; Total Number of normals: 366.
Somatic mutations of EPB42:
Generating mutation plots.
Highly correlated genes for EPB42:
Showing top 20/1045 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPB42 | FAXDC2 | 0.787112 | 3 | 0 | 3 |
| EPB42 | BAALC | 0.74206 | 3 | 0 | 3 |
| EPB42 | C10orf90 | 0.736451 | 3 | 0 | 3 |
| EPB42 | PRSS54 | 0.72276 | 3 | 0 | 3 |
| EPB42 | OOSP2 | 0.722216 | 3 | 0 | 3 |
| EPB42 | CSN2 | 0.71921 | 3 | 0 | 3 |
| EPB42 | UMOD | 0.717468 | 5 | 0 | 5 |
| EPB42 | FMN2 | 0.714319 | 3 | 0 | 3 |
| EPB42 | PHF7 | 0.708298 | 7 | 0 | 6 |
| EPB42 | PLA2G5 | 0.699284 | 3 | 0 | 3 |
| EPB42 | LCN8 | 0.69794 | 4 | 0 | 4 |
| EPB42 | KRT2 | 0.696301 | 6 | 0 | 6 |
| EPB42 | SPRN | 0.693175 | 3 | 0 | 3 |
| EPB42 | NHLRC4 | 0.691419 | 4 | 0 | 3 |
| EPB42 | CYP3A43 | 0.688664 | 7 | 0 | 7 |
| EPB42 | CRB1 | 0.686477 | 5 | 0 | 5 |
| EPB42 | MC5R | 0.685403 | 6 | 0 | 6 |
| EPB42 | SLC25A18 | 0.685358 | 3 | 0 | 3 |
| EPB42 | FMNL1 | 0.685048 | 3 | 0 | 3 |
| EPB42 | ITGA10 | 0.683396 | 6 | 0 | 5 |
For details and further investigation, click here
