| Full name: myosin heavy chain 7B | Alias Symbol: KIAA1512|dJ756N5.1|MYH14|MHC14 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 57644 | HGNC ID: HGNC:15906 | Ensembl Gene: ENSG00000078814 | OMIM ID: 609928 |
| Drug and gene relationship at DGIdb | |||
MYH7B involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of MYH7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYH7B | 57644 | 233949_s_at | 0.0268 | 0.9176 | |
| GSE20347 | MYH7B | 57644 | 215795_at | 0.0753 | 0.3500 | |
| GSE23400 | MYH7B | 57644 | 215795_at | -0.0733 | 0.0002 | |
| GSE26886 | MYH7B | 57644 | 233949_s_at | 0.2756 | 0.0065 | |
| GSE29001 | MYH7B | 57644 | 215795_at | 0.0407 | 0.7017 | |
| GSE38129 | MYH7B | 57644 | 215795_at | 0.0209 | 0.7566 | |
| GSE45670 | MYH7B | 57644 | 233949_s_at | 0.0573 | 0.5167 | |
| GSE53622 | MYH7B | 57644 | 16957 | -0.3841 | 0.0000 | |
| GSE53624 | MYH7B | 57644 | 16957 | -0.5037 | 0.0000 | |
| GSE63941 | MYH7B | 57644 | 233949_s_at | -0.0230 | 0.9100 | |
| GSE77861 | MYH7B | 57644 | 233949_s_at | -0.1468 | 0.2205 | |
| GSE97050 | MYH7B | 57644 | A_33_P3407469 | -0.3018 | 0.3207 | |
| SRP064894 | MYH7B | 57644 | RNAseq | 0.7972 | 0.0072 | |
| SRP133303 | MYH7B | 57644 | RNAseq | 0.2485 | 0.2752 | |
| SRP159526 | MYH7B | 57644 | RNAseq | 0.3339 | 0.5289 | |
| SRP193095 | MYH7B | 57644 | RNAseq | 0.6550 | 0.0009 | |
| SRP219564 | MYH7B | 57644 | RNAseq | -0.2277 | 0.4916 | |
| TCGA | MYH7B | 57644 | RNAseq | 0.0867 | 0.7359 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYH7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYH7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYH7B | 57644 | 16 | 0 | 14 | |
| GSE20123 | MYH7B | 57644 | 16 | 0 | 14 | |
| GSE43470 | MYH7B | 57644 | 12 | 0 | 31 | |
| GSE46452 | MYH7B | 57644 | 29 | 0 | 30 | |
| GSE47630 | MYH7B | 57644 | 24 | 1 | 15 | |
| GSE54993 | MYH7B | 57644 | 0 | 18 | 52 | |
| GSE54994 | MYH7B | 57644 | 25 | 0 | 28 | |
| GSE60625 | MYH7B | 57644 | 0 | 0 | 11 | |
| GSE74703 | MYH7B | 57644 | 11 | 0 | 25 | |
| GSE74704 | MYH7B | 57644 | 11 | 0 | 9 | |
| TCGA | MYH7B | 57644 | 49 | 3 | 44 |
Total number of gains: 193; Total number of losses: 22; Total Number of normals: 273.
Somatic mutations of MYH7B:
Generating mutation plots.
Highly correlated genes for MYH7B:
Showing top 20/457 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYH7B | OR51T1 | 0.783855 | 3 | 0 | 3 |
| MYH7B | KRTAP4-8 | 0.752634 | 3 | 0 | 3 |
| MYH7B | FAM71A | 0.745652 | 4 | 0 | 3 |
| MYH7B | ADRA1A | 0.732931 | 3 | 0 | 3 |
| MYH7B | GPR182 | 0.724862 | 6 | 0 | 6 |
| MYH7B | KLHL10 | 0.722395 | 3 | 0 | 3 |
| MYH7B | IGSF9B | 0.720719 | 3 | 0 | 3 |
| MYH7B | BTNL8 | 0.709904 | 5 | 0 | 5 |
| MYH7B | C1QL1 | 0.696566 | 4 | 0 | 3 |
| MYH7B | CFC1 | 0.69414 | 3 | 0 | 3 |
| MYH7B | KRTAP2-1 | 0.693071 | 4 | 0 | 4 |
| MYH7B | DHRS2 | 0.692277 | 3 | 0 | 3 |
| MYH7B | PLA2G12B | 0.691251 | 3 | 0 | 3 |
| MYH7B | KIR2DS1 | 0.686105 | 3 | 0 | 3 |
| MYH7B | ABCA4 | 0.681491 | 3 | 0 | 3 |
| MYH7B | RNF180 | 0.681345 | 3 | 0 | 3 |
| MYH7B | HBM | 0.679125 | 4 | 0 | 3 |
| MYH7B | KRT74 | 0.678846 | 3 | 0 | 3 |
| MYH7B | FABP6 | 0.678661 | 3 | 0 | 3 |
| MYH7B | NKX6-3 | 0.675686 | 3 | 0 | 3 |
For details and further investigation, click here
