| Full name: cripto, FRL-1, cryptic family 1 | Alias Symbol: CRYPTIC | ||
| Type: protein-coding gene | Cytoband: 2q21.1 | ||
| Entrez ID: 55997 | HGNC ID: HGNC:18292 | Ensembl Gene: ENSG00000136698 | OMIM ID: 605194 |
| Drug and gene relationship at DGIdb | |||
Expression of CFC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CFC1 | 55997 | 236724_at | 0.0521 | 0.8368 | |
| GSE26886 | CFC1 | 55997 | 236724_at | 0.1718 | 0.0680 | |
| GSE45670 | CFC1 | 55997 | 236724_at | 0.0630 | 0.5848 | |
| GSE63941 | CFC1 | 55997 | 236724_at | 0.1820 | 0.2263 | |
| GSE77861 | CFC1 | 55997 | 236724_at | 0.0397 | 0.7143 | |
| GSE97050 | CFC1 | 55997 | A_23_P5679 | -0.0437 | 0.8375 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of CFC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CFC1 | 55997 | 5 | 3 | 22 | |
| GSE20123 | CFC1 | 55997 | 5 | 3 | 22 | |
| GSE43470 | CFC1 | 55997 | 2 | 2 | 39 | |
| GSE46452 | CFC1 | 55997 | 1 | 3 | 55 | |
| GSE47630 | CFC1 | 55997 | 5 | 0 | 35 | |
| GSE54993 | CFC1 | 55997 | 0 | 6 | 64 | |
| GSE54994 | CFC1 | 55997 | 10 | 0 | 43 | |
| GSE60625 | CFC1 | 55997 | 0 | 3 | 8 | |
| GSE74703 | CFC1 | 55997 | 2 | 1 | 33 | |
| GSE74704 | CFC1 | 55997 | 3 | 1 | 16 | |
| TCGA | CFC1 | 55997 | 22 | 9 | 65 |
Total number of gains: 55; Total number of losses: 31; Total Number of normals: 402.
Somatic mutations of CFC1:
Generating mutation plots.
Highly correlated genes for CFC1:
Showing top 20/153 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CFC1 | SIGLEC7 | 0.784072 | 3 | 0 | 3 |
| CFC1 | HTR6 | 0.781312 | 3 | 0 | 3 |
| CFC1 | ORM1 | 0.768426 | 4 | 0 | 4 |
| CFC1 | TMEM151B | 0.766402 | 4 | 0 | 4 |
| CFC1 | PAX2 | 0.76049 | 3 | 0 | 3 |
| CFC1 | ZDHHC8 | 0.758 | 3 | 0 | 3 |
| CFC1 | CDH4 | 0.750088 | 4 | 0 | 4 |
| CFC1 | CALML6 | 0.747662 | 3 | 0 | 3 |
| CFC1 | DOK7 | 0.745959 | 3 | 0 | 3 |
| CFC1 | OPRD1 | 0.744713 | 3 | 0 | 3 |
| CFC1 | ESPNL | 0.740219 | 3 | 0 | 3 |
| CFC1 | GPR26 | 0.736668 | 3 | 0 | 3 |
| CFC1 | TMEM105 | 0.734863 | 3 | 0 | 3 |
| CFC1 | HAP1 | 0.733463 | 3 | 0 | 3 |
| CFC1 | FOXB1 | 0.72888 | 3 | 0 | 3 |
| CFC1 | LIF | 0.727161 | 3 | 0 | 3 |
| CFC1 | S1PR4 | 0.726503 | 3 | 0 | 3 |
| CFC1 | GPR150 | 0.725583 | 3 | 0 | 3 |
| CFC1 | NLRP5 | 0.721234 | 4 | 0 | 4 |
| CFC1 | CABP4 | 0.717928 | 4 | 0 | 3 |
For details and further investigation, click here
