| Full name: myopalladin | Alias Symbol: MYOP | ||
| Type: protein-coding gene | Cytoband: 10q21.3 | ||
| Entrez ID: 84665 | HGNC ID: HGNC:23246 | Ensembl Gene: ENSG00000138347 | OMIM ID: 608517 |
| Drug and gene relationship at DGIdb | |||
Expression of MYPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYPN | 84665 | 235367_at | -0.0028 | 0.9954 | |
| GSE26886 | MYPN | 84665 | 235367_at | 0.0279 | 0.8411 | |
| GSE45670 | MYPN | 84665 | 235367_at | -0.0414 | 0.5951 | |
| GSE53622 | MYPN | 84665 | 43458 | -0.7376 | 0.0000 | |
| GSE53624 | MYPN | 84665 | 43458 | -1.4630 | 0.0000 | |
| GSE63941 | MYPN | 84665 | 235367_at | 0.1079 | 0.6215 | |
| GSE77861 | MYPN | 84665 | 235367_at | -0.0695 | 0.3622 | |
| GSE97050 | MYPN | 84665 | A_24_P376120 | -0.9972 | 0.2004 | |
| TCGA | MYPN | 84665 | RNAseq | -2.1694 | 0.0143 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MYPN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYPN | 84665 | 2 | 5 | 23 | |
| GSE20123 | MYPN | 84665 | 2 | 4 | 24 | |
| GSE43470 | MYPN | 84665 | 1 | 8 | 34 | |
| GSE46452 | MYPN | 84665 | 0 | 11 | 48 | |
| GSE47630 | MYPN | 84665 | 2 | 14 | 24 | |
| GSE54993 | MYPN | 84665 | 8 | 0 | 62 | |
| GSE54994 | MYPN | 84665 | 2 | 12 | 39 | |
| GSE60625 | MYPN | 84665 | 0 | 0 | 11 | |
| GSE74703 | MYPN | 84665 | 1 | 5 | 30 | |
| GSE74704 | MYPN | 84665 | 1 | 3 | 16 | |
| TCGA | MYPN | 84665 | 10 | 22 | 64 |
Total number of gains: 29; Total number of losses: 84; Total Number of normals: 375.
Somatic mutations of MYPN:
Generating mutation plots.
Highly correlated genes for MYPN:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYPN | STARD8 | 0.687967 | 3 | 0 | 3 |
| MYPN | VPS13A-AS1 | 0.630844 | 3 | 0 | 3 |
| MYPN | CTRB2 | 0.59904 | 3 | 0 | 3 |
| MYPN | ITGB1BP2 | 0.59137 | 3 | 0 | 3 |
| MYPN | BTNL9 | 0.583138 | 4 | 0 | 3 |
| MYPN | ARHGAP33 | 0.577013 | 5 | 0 | 5 |
| MYPN | MYOM1 | 0.573048 | 4 | 0 | 3 |
| MYPN | PCOLCE-AS1 | 0.570022 | 4 | 0 | 3 |
| MYPN | NEUROD6 | 0.565875 | 3 | 0 | 3 |
| MYPN | MOG | 0.560022 | 4 | 0 | 3 |
| MYPN | CHRDL1 | 0.553696 | 3 | 0 | 3 |
| MYPN | CAMK2A | 0.548066 | 5 | 0 | 3 |
| MYPN | PRR29 | 0.538774 | 4 | 0 | 3 |
| MYPN | GIPC3 | 0.538395 | 4 | 0 | 3 |
| MYPN | PRDM8 | 0.531899 | 5 | 0 | 3 |
| MYPN | GPR62 | 0.530049 | 5 | 0 | 3 |
| MYPN | CACNA1S | 0.529313 | 4 | 0 | 3 |
| MYPN | ASB10 | 0.524555 | 4 | 0 | 3 |
| MYPN | KRT3 | 0.522887 | 4 | 0 | 3 |
| MYPN | KLRC3 | 0.521474 | 4 | 0 | 3 |
For details and further investigation, click here
