| Full name: N-acetylated alpha-linked acidic dipeptidase like 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q26.31 | ||
| Entrez ID: 254827 | HGNC ID: HGNC:23219 | Ensembl Gene: ENSG00000177694 | OMIM ID: 608806 |
| Drug and gene relationship at DGIdb | |||
Expression of NAALADL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAALADL2 | 254827 | 1557998_at | 0.1042 | 0.7591 | |
| GSE26886 | NAALADL2 | 254827 | 1557998_at | 0.0057 | 0.9632 | |
| GSE45670 | NAALADL2 | 254827 | 1557998_at | 0.0950 | 0.2338 | |
| GSE53622 | NAALADL2 | 254827 | 106208 | -0.2913 | 0.0233 | |
| GSE53624 | NAALADL2 | 254827 | 106208 | -0.4769 | 0.0000 | |
| GSE63941 | NAALADL2 | 254827 | 1557998_at | -0.1090 | 0.3507 | |
| GSE77861 | NAALADL2 | 254827 | 1557998_at | 0.0330 | 0.7194 | |
| GSE97050 | NAALADL2 | A_21_P0002710 | -0.5741 | 0.0908 | ||
| SRP007169 | NAALADL2 | 254827 | RNAseq | -0.1504 | 0.8283 | |
| SRP064894 | NAALADL2 | 254827 | RNAseq | -0.3103 | 0.3147 | |
| SRP133303 | NAALADL2 | 254827 | RNAseq | 0.5234 | 0.2881 | |
| SRP159526 | NAALADL2 | 254827 | RNAseq | 0.6624 | 0.1976 | |
| SRP193095 | NAALADL2 | 254827 | RNAseq | 0.1948 | 0.6001 | |
| SRP219564 | NAALADL2 | 254827 | RNAseq | -0.2219 | 0.7417 | |
| TCGA | NAALADL2 | 254827 | RNAseq | -0.7946 | 0.0043 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NAALADL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAALADL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAALADL2 | 254827 | 23 | 0 | 7 | |
| GSE20123 | NAALADL2 | 254827 | 23 | 0 | 7 | |
| GSE43470 | NAALADL2 | 254827 | 24 | 0 | 19 | |
| GSE46452 | NAALADL2 | 254827 | 19 | 1 | 39 | |
| GSE47630 | NAALADL2 | 254827 | 27 | 2 | 11 | |
| GSE54993 | NAALADL2 | 254827 | 1 | 17 | 52 | |
| GSE54994 | NAALADL2 | 254827 | 41 | 0 | 12 | |
| GSE60625 | NAALADL2 | 254827 | 0 | 6 | 5 | |
| GSE74703 | NAALADL2 | 254827 | 20 | 0 | 16 | |
| GSE74704 | NAALADL2 | 254827 | 15 | 0 | 5 | |
| TCGA | NAALADL2 | 254827 | 78 | 0 | 18 |
Total number of gains: 271; Total number of losses: 26; Total Number of normals: 191.
Somatic mutations of NAALADL2:
Generating mutation plots.
Highly correlated genes for NAALADL2:
Showing top 20/86 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAALADL2 | C1QTNF4 | 0.771801 | 3 | 0 | 3 |
| NAALADL2 | ILDR2 | 0.754003 | 3 | 0 | 3 |
| NAALADL2 | DIP2C | 0.741749 | 3 | 0 | 3 |
| NAALADL2 | FBXL7 | 0.711124 | 3 | 0 | 3 |
| NAALADL2 | NLGN1 | 0.696193 | 3 | 0 | 3 |
| NAALADL2 | BEND5 | 0.685359 | 3 | 0 | 3 |
| NAALADL2 | RAI2 | 0.671737 | 3 | 0 | 3 |
| NAALADL2 | CYBRD1 | 0.66708 | 3 | 0 | 3 |
| NAALADL2 | MAN1C1 | 0.666905 | 3 | 0 | 3 |
| NAALADL2 | STON1 | 0.658686 | 3 | 0 | 3 |
| NAALADL2 | RNF150 | 0.654392 | 3 | 0 | 3 |
| NAALADL2 | PRKG1 | 0.649241 | 3 | 0 | 3 |
| NAALADL2 | RSPO3 | 0.647686 | 3 | 0 | 3 |
| NAALADL2 | RASIP1 | 0.64732 | 3 | 0 | 3 |
| NAALADL2 | NPHP1 | 0.646518 | 3 | 0 | 3 |
| NAALADL2 | MAMDC2 | 0.646021 | 3 | 0 | 3 |
| NAALADL2 | TSPYL2 | 0.640632 | 3 | 0 | 3 |
| NAALADL2 | MAGEA10 | 0.637765 | 3 | 0 | 3 |
| NAALADL2 | BCHE | 0.637037 | 3 | 0 | 3 |
| NAALADL2 | ARHGEF25 | 0.63702 | 4 | 0 | 3 |
For details and further investigation, click here
