STON1

 

Full name: stonin 1 Alias Symbol: SBLF|stoned-b1
Type: protein-coding gene Cytoband: 2p16.3
Entrez ID: 11037 HGNC ID: HGNC:17003 Ensembl Gene: ENSG00000243244 OMIM ID: 605357
Drug and gene relationship at DGIdb

 

Expression of STON1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STON1 11037 213413_at -1.2386 0.2143
GSE20347 STON1 11037 213413_at 0.3681 0.3981
GSE23400 STON1 11037 213413_at -0.2572 0.1083
GSE26886 STON1 11037 213413_at 2.5351 0.0000
GSE29001 STON1 11037 213413_at 0.3593 0.3939
GSE38129 STON1 11037 213413_at -0.2575 0.5851
GSE45670 STON1 11037 213413_at -1.5336 0.0005
GSE53622 STON1 11037 25384 -0.3099 0.0945
GSE53624 STON1 11037 25384 -0.2655 0.0676
GSE63941 STON1 11037 213413_at -2.3295 0.0756
GSE77861 STON1 11037 213413_at 0.7261 0.0939
GSE97050 STON1 11037 A_23_P302005 -0.9377 0.1292
SRP007169 STON1 11037 RNAseq 3.5697 0.0000
SRP008496 STON1 11037 RNAseq 3.6434 0.0000
SRP064894 STON1 11037 RNAseq -0.0931 0.7728
SRP133303 STON1 11037 RNAseq 0.0829 0.8046
SRP159526 STON1 11037 RNAseq -0.6121 0.0659
SRP193095 STON1 11037 RNAseq 1.3086 0.0000
SRP219564 STON1 11037 RNAseq -0.7842 0.3410
TCGA STON1 11037 RNAseq -0.2984 0.0181

Upregulated datasets: 4; Downregulated datasets: 1.  


 

Survival by STON1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of STON1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STON1 11037 7 1 22
GSE20123 STON1 11037 6 1 23
GSE43470 STON1 11037 5 0 38
GSE46452 STON1 11037 1 4 54
GSE47630 STON1 11037 8 0 32
GSE54993 STON1 11037 0 5 65
GSE54994 STON1 11037 12 0 41
GSE60625 STON1 11037 0 3 8
GSE74703 STON1 11037 5 0 31
GSE74704 STON1 11037 7 1 12
TCGA STON1 11037 36 2 58

Total number of gains: 87; Total number of losses: 17; Total Number of normals: 384.  


 

Somatic mutations of STON1:

 

Generating mutation plots.

 

Highly correlated genes for STON1:

 

Showing top 20/1129 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STON1SLCO3A10.823195303
STON1RP90.776052303
STON1ATP6V1E20.771259303
STON1BVES0.75085807
STON1PAK10.740855303
STON1SGTB0.740475404
STON1RHOJ0.739246404
STON1GRAMD1A0.735577303
STON1RBMX20.731112404
STON1SFT2D30.730037303
STON1CLIP20.729806404
STON1CYS10.727422707
STON1SYNC0.726482807
STON1RASSF80.722053707
STON1TGFB1I10.7176651209
STON1LRFN50.71671403
STON1MAP1B0.71582412010
STON1LRRCC10.714541303
STON1USP420.710306303
STON1MYLK0.70775613013

For details and further investigation, click here