| Full name: MAM domain containing 2 | Alias Symbol: MGC21981 | ||
| Type: protein-coding gene | Cytoband: 9q21.12 | ||
| Entrez ID: 256691 | HGNC ID: HGNC:23673 | Ensembl Gene: ENSG00000165072 | OMIM ID: 612879 |
| Drug and gene relationship at DGIdb | |||
Expression of MAMDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAMDC2 | 256691 | 228885_at | -3.2292 | 0.0420 | |
| GSE26886 | MAMDC2 | 256691 | 228885_at | -1.2490 | 0.0019 | |
| GSE45670 | MAMDC2 | 256691 | 228885_at | -4.0046 | 0.0000 | |
| GSE53622 | MAMDC2 | 256691 | 145313 | -2.6693 | 0.0000 | |
| GSE53624 | MAMDC2 | 256691 | 145313 | -2.5964 | 0.0000 | |
| GSE63941 | MAMDC2 | 256691 | 228885_at | -1.3215 | 0.0386 | |
| GSE77861 | MAMDC2 | 256691 | 228885_at | -0.0548 | 0.8471 | |
| GSE97050 | MAMDC2 | 256691 | A_23_P157914 | -1.4589 | 0.1070 | |
| SRP007169 | MAMDC2 | 256691 | RNAseq | -2.1541 | 0.0000 | |
| SRP064894 | MAMDC2 | 256691 | RNAseq | -1.6616 | 0.0002 | |
| SRP133303 | MAMDC2 | 256691 | RNAseq | -2.3112 | 0.0000 | |
| SRP159526 | MAMDC2 | 256691 | RNAseq | -0.2874 | 0.6744 | |
| SRP193095 | MAMDC2 | 256691 | RNAseq | -1.0092 | 0.0002 | |
| TCGA | MAMDC2 | 256691 | RNAseq | -1.1875 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by MAMDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAMDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAMDC2 | 256691 | 6 | 10 | 14 | |
| GSE20123 | MAMDC2 | 256691 | 6 | 10 | 14 | |
| GSE43470 | MAMDC2 | 256691 | 6 | 5 | 32 | |
| GSE46452 | MAMDC2 | 256691 | 6 | 14 | 39 | |
| GSE47630 | MAMDC2 | 256691 | 1 | 19 | 20 | |
| GSE54993 | MAMDC2 | 256691 | 5 | 1 | 64 | |
| GSE54994 | MAMDC2 | 256691 | 4 | 13 | 36 | |
| GSE60625 | MAMDC2 | 256691 | 0 | 0 | 11 | |
| GSE74703 | MAMDC2 | 256691 | 5 | 4 | 27 | |
| GSE74704 | MAMDC2 | 256691 | 3 | 7 | 10 | |
| TCGA | MAMDC2 | 256691 | 19 | 28 | 49 |
Total number of gains: 61; Total number of losses: 111; Total Number of normals: 316.
Somatic mutations of MAMDC2:
Generating mutation plots.
Highly correlated genes for MAMDC2:
Showing top 20/1381 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAMDC2 | FXYD1 | 0.880837 | 3 | 0 | 3 |
| MAMDC2 | CFD | 0.865798 | 5 | 0 | 5 |
| MAMDC2 | SLITRK3 | 0.864854 | 5 | 0 | 5 |
| MAMDC2 | SORCS1 | 0.863761 | 4 | 0 | 4 |
| MAMDC2 | CYP21A2 | 0.854096 | 3 | 0 | 3 |
| MAMDC2 | ITGA9 | 0.852152 | 5 | 0 | 5 |
| MAMDC2 | XKR4 | 0.848847 | 5 | 0 | 5 |
| MAMDC2 | APOD | 0.845121 | 5 | 0 | 5 |
| MAMDC2 | CLEC3B | 0.843818 | 3 | 0 | 3 |
| MAMDC2 | PRELP | 0.833536 | 5 | 0 | 5 |
| MAMDC2 | PGM5 | 0.825931 | 6 | 0 | 5 |
| MAMDC2 | CACNB2 | 0.825579 | 5 | 0 | 5 |
| MAMDC2 | ADAMTS9-AS2 | 0.82392 | 4 | 0 | 4 |
| MAMDC2 | DMPK | 0.82216 | 3 | 0 | 3 |
| MAMDC2 | PGR | 0.818951 | 5 | 0 | 5 |
| MAMDC2 | NPY1R | 0.814751 | 3 | 0 | 3 |
| MAMDC2 | MYOCD | 0.813924 | 6 | 0 | 6 |
| MAMDC2 | CRBN | 0.812022 | 3 | 0 | 3 |
| MAMDC2 | BOC | 0.81142 | 5 | 0 | 5 |
| MAMDC2 | FLNC | 0.811309 | 6 | 0 | 6 |
For details and further investigation, click here
