| Full name: cytochrome b reductase 1 | Alias Symbol: DCYTB|FLJ23462|FRRS3|CYB561A2 | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 79901 | HGNC ID: HGNC:20797 | Ensembl Gene: ENSG00000071967 | OMIM ID: 605745 |
| Drug and gene relationship at DGIdb | |||
Expression of CYBRD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYBRD1 | 79901 | 222453_at | -0.9423 | 0.3031 | |
| GSE20347 | CYBRD1 | 79901 | 217889_s_at | 0.3815 | 0.1321 | |
| GSE23400 | CYBRD1 | 79901 | 217889_s_at | 0.2294 | 0.0333 | |
| GSE26886 | CYBRD1 | 79901 | 222453_at | 1.3142 | 0.0121 | |
| GSE29001 | CYBRD1 | 79901 | 217889_s_at | 0.5672 | 0.0047 | |
| GSE38129 | CYBRD1 | 79901 | 217889_s_at | 0.3006 | 0.2717 | |
| GSE45670 | CYBRD1 | 79901 | 222453_at | -2.0878 | 0.0000 | |
| GSE53622 | CYBRD1 | 79901 | 67739 | -0.8150 | 0.0000 | |
| GSE53624 | CYBRD1 | 79901 | 65894 | -0.9386 | 0.0000 | |
| GSE63941 | CYBRD1 | 79901 | 222453_at | -4.2951 | 0.0058 | |
| GSE77861 | CYBRD1 | 79901 | 222453_at | 0.3251 | 0.4941 | |
| GSE97050 | CYBRD1 | 79901 | A_24_P345451 | -0.6868 | 0.1140 | |
| SRP007169 | CYBRD1 | 79901 | RNAseq | 0.6865 | 0.1693 | |
| SRP008496 | CYBRD1 | 79901 | RNAseq | 0.9404 | 0.0012 | |
| SRP064894 | CYBRD1 | 79901 | RNAseq | -0.5065 | 0.1545 | |
| SRP133303 | CYBRD1 | 79901 | RNAseq | -1.1038 | 0.0005 | |
| SRP159526 | CYBRD1 | 79901 | RNAseq | -0.5294 | 0.0791 | |
| SRP193095 | CYBRD1 | 79901 | RNAseq | -1.0110 | 0.0016 | |
| SRP219564 | CYBRD1 | 79901 | RNAseq | -0.3649 | 0.5770 | |
| TCGA | CYBRD1 | 79901 | RNAseq | -0.4298 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by CYBRD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYBRD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYBRD1 | 79901 | 8 | 0 | 22 | |
| GSE20123 | CYBRD1 | 79901 | 8 | 0 | 22 | |
| GSE43470 | CYBRD1 | 79901 | 5 | 1 | 37 | |
| GSE46452 | CYBRD1 | 79901 | 1 | 4 | 54 | |
| GSE47630 | CYBRD1 | 79901 | 5 | 3 | 32 | |
| GSE54993 | CYBRD1 | 79901 | 0 | 5 | 65 | |
| GSE54994 | CYBRD1 | 79901 | 11 | 3 | 39 | |
| GSE60625 | CYBRD1 | 79901 | 0 | 3 | 8 | |
| GSE74703 | CYBRD1 | 79901 | 4 | 1 | 31 | |
| GSE74704 | CYBRD1 | 79901 | 5 | 0 | 15 | |
| TCGA | CYBRD1 | 79901 | 27 | 6 | 63 |
Total number of gains: 74; Total number of losses: 26; Total Number of normals: 388.
Somatic mutations of CYBRD1:
Generating mutation plots.
Highly correlated genes for CYBRD1:
Showing top 20/874 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYBRD1 | CYP21A2 | 0.756274 | 3 | 0 | 3 |
| CYBRD1 | CLEC3B | 0.743815 | 3 | 0 | 3 |
| CYBRD1 | NR2F1 | 0.741503 | 3 | 0 | 3 |
| CYBRD1 | TCEAL6 | 0.736452 | 3 | 0 | 3 |
| CYBRD1 | ZEB1 | 0.735383 | 3 | 0 | 3 |
| CYBRD1 | IL6ST | 0.731119 | 6 | 0 | 6 |
| CYBRD1 | RHOU | 0.724598 | 5 | 0 | 5 |
| CYBRD1 | TNFSF12 | 0.721182 | 4 | 0 | 4 |
| CYBRD1 | SORCS1 | 0.716657 | 4 | 0 | 4 |
| CYBRD1 | SHE | 0.713969 | 3 | 0 | 3 |
| CYBRD1 | CELF2 | 0.708085 | 6 | 0 | 6 |
| CYBRD1 | MRGPRF | 0.706872 | 8 | 0 | 8 |
| CYBRD1 | C5orf24 | 0.701815 | 4 | 0 | 4 |
| CYBRD1 | ARHGAP31 | 0.699327 | 5 | 0 | 5 |
| CYBRD1 | MAT2A | 0.698977 | 3 | 0 | 3 |
| CYBRD1 | C1QTNF2 | 0.696624 | 5 | 0 | 4 |
| CYBRD1 | ANGPTL1 | 0.695375 | 6 | 0 | 6 |
| CYBRD1 | RERG | 0.692589 | 6 | 0 | 6 |
| CYBRD1 | PRICKLE2 | 0.69188 | 6 | 0 | 6 |
| CYBRD1 | ACTG2 | 0.688869 | 8 | 0 | 7 |
For details and further investigation, click here
