| Full name: non-SMC condensin II complex subunit D3 | Alias Symbol: hCAP-D3|CAP-D3|hHCP-6|KIAA0056|FLJ42888|hcp-6 | ||
| Type: protein-coding gene | Cytoband: 11q25 | ||
| Entrez ID: 23310 | HGNC ID: HGNC:28952 | Ensembl Gene: ENSG00000151503 | OMIM ID: 609276 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NCAPD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCAPD3 | 23310 | 212789_at | 0.8768 | 0.0181 | |
| GSE20347 | NCAPD3 | 23310 | 212789_at | 0.5369 | 0.0001 | |
| GSE23400 | NCAPD3 | 23310 | 212789_at | 0.4926 | 0.0000 | |
| GSE26886 | NCAPD3 | 23310 | 212789_at | 0.8927 | 0.0000 | |
| GSE29001 | NCAPD3 | 23310 | 212789_at | 0.3965 | 0.2626 | |
| GSE38129 | NCAPD3 | 23310 | 212789_at | 0.6361 | 0.0000 | |
| GSE45670 | NCAPD3 | 23310 | 212789_at | 0.3824 | 0.0230 | |
| GSE53622 | NCAPD3 | 23310 | 3370 | 0.4682 | 0.0000 | |
| GSE53624 | NCAPD3 | 23310 | 18541 | 0.7557 | 0.0000 | |
| GSE63941 | NCAPD3 | 23310 | 212789_at | 1.4321 | 0.0021 | |
| GSE77861 | NCAPD3 | 23310 | 212789_at | 0.3350 | 0.3115 | |
| GSE97050 | NCAPD3 | 23310 | A_32_P71447 | 0.5203 | 0.1439 | |
| SRP007169 | NCAPD3 | 23310 | RNAseq | 1.4035 | 0.0006 | |
| SRP008496 | NCAPD3 | 23310 | RNAseq | 1.4277 | 0.0000 | |
| SRP064894 | NCAPD3 | 23310 | RNAseq | 0.1865 | 0.3557 | |
| SRP133303 | NCAPD3 | 23310 | RNAseq | 0.4196 | 0.0431 | |
| SRP159526 | NCAPD3 | 23310 | RNAseq | 0.3775 | 0.1685 | |
| SRP193095 | NCAPD3 | 23310 | RNAseq | 0.3298 | 0.0021 | |
| SRP219564 | NCAPD3 | 23310 | RNAseq | 0.5359 | 0.1036 | |
| TCGA | NCAPD3 | 23310 | RNAseq | 0.2384 | 0.0002 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by NCAPD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCAPD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCAPD3 | 23310 | 0 | 15 | 15 | |
| GSE20123 | NCAPD3 | 23310 | 0 | 15 | 15 | |
| GSE43470 | NCAPD3 | 23310 | 2 | 8 | 33 | |
| GSE46452 | NCAPD3 | 23310 | 3 | 26 | 30 | |
| GSE47630 | NCAPD3 | 23310 | 2 | 19 | 19 | |
| GSE54993 | NCAPD3 | 23310 | 10 | 0 | 60 | |
| GSE54994 | NCAPD3 | 23310 | 5 | 18 | 30 | |
| GSE60625 | NCAPD3 | 23310 | 0 | 3 | 8 | |
| GSE74703 | NCAPD3 | 23310 | 1 | 5 | 30 | |
| GSE74704 | NCAPD3 | 23310 | 0 | 11 | 9 | |
| TCGA | NCAPD3 | 23310 | 6 | 49 | 41 |
Total number of gains: 29; Total number of losses: 169; Total Number of normals: 290.
Somatic mutations of NCAPD3:
Generating mutation plots.
Highly correlated genes for NCAPD3:
Showing top 20/1641 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCAPD3 | TMEM170A | 0.823343 | 3 | 0 | 3 |
| NCAPD3 | ZNF680 | 0.782754 | 3 | 0 | 3 |
| NCAPD3 | LRRC58 | 0.771148 | 4 | 0 | 4 |
| NCAPD3 | TRUB1 | 0.75074 | 4 | 0 | 3 |
| NCAPD3 | C15orf61 | 0.745908 | 3 | 0 | 3 |
| NCAPD3 | ZNF584 | 0.741637 | 3 | 0 | 3 |
| NCAPD3 | MMS22L | 0.739893 | 3 | 0 | 3 |
| NCAPD3 | NCAPG | 0.728461 | 10 | 0 | 9 |
| NCAPD3 | PHF6 | 0.72446 | 3 | 0 | 3 |
| NCAPD3 | DMXL2 | 0.722388 | 3 | 0 | 3 |
| NCAPD3 | METTL23 | 0.72137 | 7 | 0 | 7 |
| NCAPD3 | SLC25A19 | 0.720686 | 5 | 0 | 5 |
| NCAPD3 | LPCAT2 | 0.720474 | 3 | 0 | 3 |
| NCAPD3 | KIF15 | 0.719463 | 11 | 0 | 10 |
| NCAPD3 | ZNF668 | 0.714827 | 3 | 0 | 3 |
| NCAPD3 | CPT1C | 0.713326 | 4 | 0 | 4 |
| NCAPD3 | ELOVL7 | 0.713035 | 3 | 0 | 3 |
| NCAPD3 | DKC1 | 0.710186 | 3 | 0 | 3 |
| NCAPD3 | TTK | 0.710023 | 12 | 0 | 11 |
| NCAPD3 | UBE2T | 0.70861 | 9 | 0 | 8 |
For details and further investigation, click here
