| Full name: ubiquitin conjugating enzyme E2 T | Alias Symbol: HSPC150|FANCT | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 29089 | HGNC ID: HGNC:25009 | Ensembl Gene: ENSG00000077152 | OMIM ID: 610538 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
UBE2T involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03460 | Fanconi anemia pathway |
Expression of UBE2T:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2T | 29089 | 223229_at | 1.7197 | 0.0036 | |
| GSE26886 | UBE2T | 29089 | 223229_at | 1.4992 | 0.0000 | |
| GSE45670 | UBE2T | 29089 | 223229_at | 1.4797 | 0.0000 | |
| GSE53622 | UBE2T | 29089 | 79048 | 1.5418 | 0.0000 | |
| GSE53624 | UBE2T | 29089 | 79048 | 2.1416 | 0.0000 | |
| GSE63941 | UBE2T | 29089 | 223229_at | 3.1853 | 0.0000 | |
| GSE77861 | UBE2T | 29089 | 223229_at | 1.1063 | 0.0044 | |
| GSE97050 | UBE2T | 29089 | A_23_P115482 | 0.9726 | 0.1399 | |
| SRP007169 | UBE2T | 29089 | RNAseq | 1.7086 | 0.0002 | |
| SRP008496 | UBE2T | 29089 | RNAseq | 1.7489 | 0.0001 | |
| SRP064894 | UBE2T | 29089 | RNAseq | 1.7450 | 0.0000 | |
| SRP133303 | UBE2T | 29089 | RNAseq | 1.9224 | 0.0000 | |
| SRP159526 | UBE2T | 29089 | RNAseq | 1.9900 | 0.0000 | |
| SRP193095 | UBE2T | 29089 | RNAseq | 1.2627 | 0.0000 | |
| SRP219564 | UBE2T | 29089 | RNAseq | 1.8933 | 0.0004 | |
| TCGA | UBE2T | 29089 | RNAseq | 1.3158 | 0.0000 |
Upregulated datasets: 15; Downregulated datasets: 0.
Survival by UBE2T expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2T:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2T | 29089 | 11 | 0 | 19 | |
| GSE20123 | UBE2T | 29089 | 11 | 0 | 19 | |
| GSE43470 | UBE2T | 29089 | 6 | 0 | 37 | |
| GSE46452 | UBE2T | 29089 | 3 | 1 | 55 | |
| GSE47630 | UBE2T | 29089 | 14 | 0 | 26 | |
| GSE54993 | UBE2T | 29089 | 0 | 6 | 64 | |
| GSE54994 | UBE2T | 29089 | 15 | 0 | 38 | |
| GSE60625 | UBE2T | 29089 | 0 | 0 | 11 | |
| GSE74703 | UBE2T | 29089 | 6 | 0 | 30 | |
| GSE74704 | UBE2T | 29089 | 5 | 0 | 15 | |
| TCGA | UBE2T | 29089 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of UBE2T:
Generating mutation plots.
Highly correlated genes for UBE2T:
Showing top 20/2004 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2T | CKS1B | 0.880622 | 9 | 0 | 9 |
| UBE2T | NCAPH | 0.864151 | 5 | 0 | 5 |
| UBE2T | SPAG5 | 0.863834 | 9 | 0 | 9 |
| UBE2T | KNSTRN | 0.863428 | 7 | 0 | 7 |
| UBE2T | KIF2C | 0.854311 | 8 | 0 | 8 |
| UBE2T | CDC45 | 0.854116 | 8 | 0 | 8 |
| UBE2T | CENPF | 0.849273 | 9 | 0 | 8 |
| UBE2T | KIF14 | 0.848416 | 9 | 0 | 9 |
| UBE2T | DTL | 0.842097 | 9 | 0 | 9 |
| UBE2T | RFC4 | 0.841363 | 9 | 0 | 9 |
| UBE2T | MYBL2 | 0.839542 | 8 | 0 | 8 |
| UBE2T | UBE2S | 0.839483 | 5 | 0 | 5 |
| UBE2T | DNMT1 | 0.839057 | 8 | 0 | 8 |
| UBE2T | RAD51AP1 | 0.836944 | 9 | 0 | 9 |
| UBE2T | TTK | 0.835709 | 8 | 0 | 8 |
| UBE2T | TPX2 | 0.834305 | 9 | 0 | 9 |
| UBE2T | UBE2C | 0.834202 | 9 | 0 | 8 |
| UBE2T | KIF15 | 0.834088 | 7 | 0 | 7 |
| UBE2T | GINS1 | 0.831818 | 8 | 0 | 8 |
| UBE2T | BLM | 0.829577 | 9 | 0 | 8 |
For details and further investigation, click here
