KIF15

 

Full name: kinesin family member 15 Alias Symbol: HKLP2|NY-BR-62
Type: protein-coding gene Cytoband: 3p21.31
Entrez ID: 56992 HGNC ID: HGNC:17273 Ensembl Gene: ENSG00000163808 OMIM ID: 617569
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of KIF15:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KIF15 56992 219306_at 1.4773 0.0248
GSE20347 KIF15 56992 219306_at 1.2083 0.0000
GSE23400 KIF15 56992 219306_at 0.7367 0.0000
GSE26886 KIF15 56992 219306_at -0.2479 0.5276
GSE29001 KIF15 56992 219306_at 1.1689 0.0054
GSE38129 KIF15 56992 219306_at 1.5411 0.0000
GSE45670 KIF15 56992 219306_at 1.0392 0.0000
GSE53622 KIF15 56992 148768 0.9771 0.0000
GSE53624 KIF15 56992 148768 1.2634 0.0000
GSE63941 KIF15 56992 219306_at 2.8091 0.0000
GSE77861 KIF15 56992 219306_at 0.3396 0.2748
GSE97050 KIF15 56992 A_23_P80902 0.7697 0.1296
SRP007169 KIF15 56992 RNAseq 2.6108 0.0004
SRP008496 KIF15 56992 RNAseq 1.8805 0.0003
SRP064894 KIF15 56992 RNAseq 0.7430 0.0130
SRP133303 KIF15 56992 RNAseq 1.0307 0.0004
SRP159526 KIF15 56992 RNAseq 1.0076 0.0057
SRP193095 KIF15 56992 RNAseq 0.4220 0.0034
SRP219564 KIF15 56992 RNAseq 0.5587 0.3478
TCGA KIF15 56992 RNAseq 1.2267 0.0000

Upregulated datasets: 12; Downregulated datasets: 0.  

 

Survival by KIF15 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KIF15:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KIF15 56992 0 17 13
GSE20123 KIF15 56992 0 18 12
GSE43470 KIF15 56992 0 21 22
GSE46452 KIF15 56992 2 17 40
GSE47630 KIF15 56992 1 24 15
GSE54993 KIF15 56992 7 2 61
GSE54994 KIF15 56992 0 35 18
GSE60625 KIF15 56992 5 0 6
GSE74703 KIF15 56992 0 16 20
GSE74704 KIF15 56992 0 13 7
TCGA KIF15 56992 1 74 21

Total number of gains: 16; Total number of losses: 237; Total Number of normals: 235.  

 

Somatic mutations of KIF15:

 

Generating mutation plots.

 

Highly correlated genes for KIF15:

 

Showing top 20/1693 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KIF15UBE2T0.834088707
KIF15RACGAP10.826706909
KIF15BUB1B0.825998908
KIF15GINS10.82401611011
KIF15CENPF0.82239812011
KIF15GMNN0.82157511011
KIF15KIF110.8194712012
KIF15CEP550.81900112012
KIF15ATAD20.81846312012
KIF15CDK10.81640212012
KIF15TTK0.80776913012
KIF15BUB10.8070710010
KIF15NEK20.79542513013
KIF15PLK40.7948610010
KIF15MELK0.79388612012
KIF15FIGNL10.79325707
KIF15KIF140.78936312011
KIF15CENPN0.78893111011
KIF15NUSAP10.78646213011
KIF15TPX20.78598612011

For details and further investigation, click here