| Full name: NADH:ubiquinone oxidoreductase subunit A11 | Alias Symbol: B14.7 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126328 | HGNC ID: HGNC:20371 | Ensembl Gene: ENSG00000174886 | OMIM ID: 612638 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFA11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFA11 | 126328 | 228690_s_at | 0.2244 | 0.5509 | |
| GSE26886 | NDUFA11 | 126328 | 228690_s_at | 0.1131 | 0.5145 | |
| GSE45670 | NDUFA11 | 126328 | 228690_s_at | -0.0611 | 0.5379 | |
| GSE63941 | NDUFA11 | 126328 | 228690_s_at | -0.3427 | 0.1738 | |
| GSE77861 | NDUFA11 | 126328 | 228690_s_at | -0.2186 | 0.1539 | |
| GSE97050 | NDUFA11 | 126328 | A_23_P320185 | -0.3123 | 0.1808 | |
| SRP007169 | NDUFA11 | 126328 | RNAseq | -1.5690 | 0.0000 | |
| SRP008496 | NDUFA11 | 126328 | RNAseq | -1.4699 | 0.0000 | |
| SRP064894 | NDUFA11 | 126328 | RNAseq | 0.2078 | 0.6066 | |
| SRP133303 | NDUFA11 | 126328 | RNAseq | -0.5326 | 0.0008 | |
| SRP159526 | NDUFA11 | 126328 | RNAseq | -0.4747 | 0.0056 | |
| SRP193095 | NDUFA11 | 126328 | RNAseq | -0.7738 | 0.0000 | |
| SRP219564 | NDUFA11 | 126328 | RNAseq | -0.4604 | 0.2053 | |
| TCGA | NDUFA11 | 126328 | RNAseq | 0.0050 | 0.9223 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NDUFA11 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NDUFA11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFA11 | 126328 | 5 | 3 | 22 | |
| GSE20123 | NDUFA11 | 126328 | 4 | 2 | 24 | |
| GSE43470 | NDUFA11 | 126328 | 2 | 6 | 35 | |
| GSE46452 | NDUFA11 | 126328 | 47 | 1 | 11 | |
| GSE47630 | NDUFA11 | 126328 | 5 | 7 | 28 | |
| GSE54993 | NDUFA11 | 126328 | 16 | 3 | 51 | |
| GSE54994 | NDUFA11 | 126328 | 6 | 16 | 31 | |
| GSE60625 | NDUFA11 | 126328 | 9 | 0 | 2 | |
| GSE74703 | NDUFA11 | 126328 | 2 | 4 | 30 | |
| GSE74704 | NDUFA11 | 126328 | 1 | 2 | 17 | |
| TCGA | NDUFA11 | 126328 | 9 | 18 | 69 |
Total number of gains: 106; Total number of losses: 62; Total Number of normals: 320.
Somatic mutations of NDUFA11:
Generating mutation plots.
Highly correlated genes for NDUFA11:
Showing top 20/144 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFA11 | UROS | 0.834018 | 3 | 0 | 3 |
| NDUFA11 | UPF1 | 0.781484 | 3 | 0 | 3 |
| NDUFA11 | ZNF791 | 0.769987 | 3 | 0 | 3 |
| NDUFA11 | USP20 | 0.767415 | 3 | 0 | 3 |
| NDUFA11 | ATP6V1G2 | 0.757649 | 3 | 0 | 3 |
| NDUFA11 | MCCC1 | 0.751581 | 3 | 0 | 3 |
| NDUFA11 | PPP1R37 | 0.746855 | 3 | 0 | 3 |
| NDUFA11 | GLB1L2 | 0.740879 | 3 | 0 | 3 |
| NDUFA11 | PNPLA6 | 0.73935 | 3 | 0 | 3 |
| NDUFA11 | RBM15B | 0.732545 | 3 | 0 | 3 |
| NDUFA11 | C22orf31 | 0.729474 | 3 | 0 | 3 |
| NDUFA11 | TSEN34 | 0.72214 | 4 | 0 | 3 |
| NDUFA11 | MLLT1 | 0.72204 | 4 | 0 | 3 |
| NDUFA11 | MRPS18C | 0.721644 | 3 | 0 | 3 |
| NDUFA11 | ZNF155 | 0.715752 | 3 | 0 | 3 |
| NDUFA11 | ZRANB2 | 0.710737 | 3 | 0 | 3 |
| NDUFA11 | ZNF35 | 0.70296 | 3 | 0 | 3 |
| NDUFA11 | UQCRFS1 | 0.702717 | 3 | 0 | 3 |
| NDUFA11 | CCNJ | 0.699055 | 3 | 0 | 3 |
| NDUFA11 | RHOC | 0.698877 | 3 | 0 | 3 |
For details and further investigation, click here
