| Full name: ubiquitin specific peptidase 20 | Alias Symbol: KIAA1003 | ||
| Type: protein-coding gene | Cytoband: 9q34.2 | ||
| Entrez ID: 10868 | HGNC ID: HGNC:12619 | Ensembl Gene: ENSG00000136878 | OMIM ID: 615143 |
| Drug and gene relationship at DGIdb | |||
Expression of USP20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP20 | 10868 | 203965_at | 0.1969 | 0.6472 | |
| GSE20347 | USP20 | 10868 | 203965_at | 0.0204 | 0.8460 | |
| GSE23400 | USP20 | 10868 | 203965_at | -0.0145 | 0.7878 | |
| GSE26886 | USP20 | 10868 | 203965_at | 0.3123 | 0.0935 | |
| GSE29001 | USP20 | 10868 | 203965_at | 0.0416 | 0.8210 | |
| GSE38129 | USP20 | 10868 | 203965_at | -0.1171 | 0.4134 | |
| GSE45670 | USP20 | 10868 | 203965_at | 0.0438 | 0.7247 | |
| GSE53622 | USP20 | 10868 | 32697 | -0.1704 | 0.0253 | |
| GSE53624 | USP20 | 10868 | 32697 | 0.0223 | 0.7746 | |
| GSE63941 | USP20 | 10868 | 203965_at | -0.4365 | 0.1739 | |
| GSE77861 | USP20 | 10868 | 203965_at | -0.0310 | 0.8888 | |
| GSE97050 | USP20 | 10868 | A_23_P217028 | -0.1649 | 0.5421 | |
| SRP007169 | USP20 | 10868 | RNAseq | 0.2990 | 0.4771 | |
| SRP008496 | USP20 | 10868 | RNAseq | 0.2629 | 0.3500 | |
| SRP064894 | USP20 | 10868 | RNAseq | 0.2063 | 0.3557 | |
| SRP133303 | USP20 | 10868 | RNAseq | -0.4000 | 0.0041 | |
| SRP159526 | USP20 | 10868 | RNAseq | 0.0421 | 0.8739 | |
| SRP193095 | USP20 | 10868 | RNAseq | 0.0040 | 0.9769 | |
| SRP219564 | USP20 | 10868 | RNAseq | -0.1597 | 0.6998 | |
| TCGA | USP20 | 10868 | RNAseq | -0.1433 | 0.0050 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USP20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP20 | 10868 | 6 | 9 | 15 | |
| GSE20123 | USP20 | 10868 | 6 | 9 | 15 | |
| GSE43470 | USP20 | 10868 | 5 | 7 | 31 | |
| GSE46452 | USP20 | 10868 | 6 | 13 | 40 | |
| GSE47630 | USP20 | 10868 | 3 | 16 | 21 | |
| GSE54993 | USP20 | 10868 | 3 | 3 | 64 | |
| GSE54994 | USP20 | 10868 | 12 | 9 | 32 | |
| GSE60625 | USP20 | 10868 | 0 | 0 | 11 | |
| GSE74703 | USP20 | 10868 | 5 | 5 | 26 | |
| GSE74704 | USP20 | 10868 | 3 | 7 | 10 | |
| TCGA | USP20 | 10868 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.
Somatic mutations of USP20:
Generating mutation plots.
Highly correlated genes for USP20:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP20 | CBX6 | 0.820188 | 3 | 0 | 3 |
| USP20 | ZNF784 | 0.812006 | 3 | 0 | 3 |
| USP20 | ARFGAP2 | 0.773786 | 3 | 0 | 3 |
| USP20 | NDUFA11 | 0.767415 | 3 | 0 | 3 |
| USP20 | MEPCE | 0.731664 | 3 | 0 | 3 |
| USP20 | WDR25 | 0.730966 | 3 | 0 | 3 |
| USP20 | FOXC1 | 0.72698 | 3 | 0 | 3 |
| USP20 | KCND3 | 0.722059 | 3 | 0 | 3 |
| USP20 | PBX2 | 0.719119 | 4 | 0 | 3 |
| USP20 | MED13 | 0.707386 | 3 | 0 | 3 |
| USP20 | DCAF16 | 0.704842 | 3 | 0 | 3 |
| USP20 | TTLL1 | 0.703325 | 5 | 0 | 4 |
| USP20 | CRISPLD2 | 0.702016 | 3 | 0 | 3 |
| USP20 | PIK3CA | 0.699863 | 3 | 0 | 3 |
| USP20 | ZNF830 | 0.698398 | 3 | 0 | 3 |
| USP20 | NUDT3 | 0.697482 | 4 | 0 | 3 |
| USP20 | HSPG2 | 0.697115 | 4 | 0 | 3 |
| USP20 | UBE2O | 0.693847 | 3 | 0 | 3 |
| USP20 | VWA1 | 0.690838 | 4 | 0 | 4 |
| USP20 | ARMCX2 | 0.690805 | 3 | 0 | 3 |
For details and further investigation, click here
