| Full name: ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | Alias Symbol: RIS1|RIP1|UQCR5|RISP | ||
| Type: protein-coding gene | Cytoband: 19q12 | ||
| Entrez ID: 7386 | HGNC ID: HGNC:12587 | Ensembl Gene: ENSG00000169021 | OMIM ID: 191327 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UQCRFS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UQCRFS1 | 7386 | 208909_at | -0.2044 | 0.6766 | |
| GSE20347 | UQCRFS1 | 7386 | 208909_at | -0.3895 | 0.0318 | |
| GSE23400 | UQCRFS1 | 7386 | 208909_at | 0.1170 | 0.2558 | |
| GSE26886 | UQCRFS1 | 7386 | 208909_at | -0.2384 | 0.3380 | |
| GSE29001 | UQCRFS1 | 7386 | 208909_at | -0.1452 | 0.7418 | |
| GSE38129 | UQCRFS1 | 7386 | 208909_at | -0.1973 | 0.2899 | |
| GSE45670 | UQCRFS1 | 7386 | 208909_at | 0.0214 | 0.9186 | |
| GSE53622 | UQCRFS1 | 7386 | 67435 | -0.5345 | 0.0000 | |
| GSE53624 | UQCRFS1 | 7386 | 67435 | -0.1842 | 0.0084 | |
| GSE63941 | UQCRFS1 | 7386 | 208909_at | 0.5249 | 0.1026 | |
| GSE77861 | UQCRFS1 | 7386 | 208909_at | -0.1025 | 0.7623 | |
| GSE97050 | UQCRFS1 | 7386 | A_23_P153586 | -0.3826 | 0.1726 | |
| SRP007169 | UQCRFS1 | 7386 | RNAseq | -0.3670 | 0.4140 | |
| SRP008496 | UQCRFS1 | 7386 | RNAseq | -0.6156 | 0.0122 | |
| SRP064894 | UQCRFS1 | 7386 | RNAseq | -0.2994 | 0.1626 | |
| SRP133303 | UQCRFS1 | 7386 | RNAseq | -0.4215 | 0.0386 | |
| SRP159526 | UQCRFS1 | 7386 | RNAseq | 0.2091 | 0.5747 | |
| SRP193095 | UQCRFS1 | 7386 | RNAseq | -0.5974 | 0.0000 | |
| SRP219564 | UQCRFS1 | 7386 | RNAseq | -0.5365 | 0.1221 | |
| TCGA | UQCRFS1 | 7386 | RNAseq | -0.1924 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UQCRFS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UQCRFS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UQCRFS1 | 7386 | 6 | 7 | 17 | |
| GSE20123 | UQCRFS1 | 7386 | 6 | 6 | 18 | |
| GSE43470 | UQCRFS1 | 7386 | 6 | 6 | 31 | |
| GSE46452 | UQCRFS1 | 7386 | 47 | 1 | 11 | |
| GSE47630 | UQCRFS1 | 7386 | 8 | 6 | 26 | |
| GSE54993 | UQCRFS1 | 7386 | 17 | 3 | 50 | |
| GSE54994 | UQCRFS1 | 7386 | 7 | 11 | 35 | |
| GSE60625 | UQCRFS1 | 7386 | 9 | 0 | 2 | |
| GSE74703 | UQCRFS1 | 7386 | 6 | 4 | 26 | |
| GSE74704 | UQCRFS1 | 7386 | 5 | 4 | 11 | |
| TCGA | UQCRFS1 | 7386 | 17 | 14 | 65 |
Total number of gains: 134; Total number of losses: 62; Total Number of normals: 292.
Somatic mutations of UQCRFS1:
Generating mutation plots.
Highly correlated genes for UQCRFS1:
Showing top 20/544 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UQCRFS1 | EIF2D | 0.816386 | 3 | 0 | 3 |
| UQCRFS1 | ZNF627 | 0.785325 | 3 | 0 | 3 |
| UQCRFS1 | AP3M1 | 0.777778 | 3 | 0 | 3 |
| UQCRFS1 | SERTAD1 | 0.776986 | 3 | 0 | 3 |
| UQCRFS1 | STK40 | 0.7632 | 4 | 0 | 4 |
| UQCRFS1 | EGLN2 | 0.759756 | 3 | 0 | 3 |
| UQCRFS1 | METAP2 | 0.757996 | 3 | 0 | 3 |
| UQCRFS1 | USP54 | 0.751676 | 3 | 0 | 3 |
| UQCRFS1 | MCOLN1 | 0.748084 | 3 | 0 | 3 |
| UQCRFS1 | TCEAL4 | 0.745905 | 3 | 0 | 3 |
| UQCRFS1 | BACE2 | 0.73685 | 3 | 0 | 3 |
| UQCRFS1 | GPANK1 | 0.736357 | 3 | 0 | 3 |
| UQCRFS1 | TTLL1 | 0.735018 | 3 | 0 | 3 |
| UQCRFS1 | RERG | 0.730931 | 3 | 0 | 3 |
| UQCRFS1 | NDN | 0.729244 | 4 | 0 | 4 |
| UQCRFS1 | RRAGB | 0.728882 | 4 | 0 | 3 |
| UQCRFS1 | ZNF564 | 0.728312 | 4 | 0 | 3 |
| UQCRFS1 | ZNF830 | 0.723996 | 3 | 0 | 3 |
| UQCRFS1 | BEX5 | 0.718545 | 4 | 0 | 3 |
| UQCRFS1 | COPS2 | 0.717021 | 3 | 0 | 3 |
For details and further investigation, click here
