| Full name: zinc finger RANBP2-type containing 2 | Alias Symbol: ZIS|ZIS1|ZIS2 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 9406 | HGNC ID: HGNC:13058 | Ensembl Gene: ENSG00000132485 | OMIM ID: 604347 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZRANB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZRANB2 | 9406 | 223716_s_at | -0.0849 | 0.8934 | |
| GSE26886 | ZRANB2 | 9406 | 223716_s_at | -0.4667 | 0.0147 | |
| GSE45670 | ZRANB2 | 9406 | 223716_s_at | -0.3406 | 0.0012 | |
| GSE53622 | ZRANB2 | 9406 | 143547 | 0.0498 | 0.4639 | |
| GSE53624 | ZRANB2 | 9406 | 143547 | 0.0585 | 0.3279 | |
| GSE63941 | ZRANB2 | 9406 | 223716_s_at | -0.0392 | 0.9386 | |
| GSE77861 | ZRANB2 | 9406 | 223716_s_at | -0.2578 | 0.3284 | |
| GSE97050 | ZRANB2 | 9406 | A_24_P242299 | -0.2788 | 0.2959 | |
| SRP007169 | ZRANB2 | 9406 | RNAseq | -0.2231 | 0.4807 | |
| SRP008496 | ZRANB2 | 9406 | RNAseq | -0.1832 | 0.2513 | |
| SRP064894 | ZRANB2 | 9406 | RNAseq | -0.0929 | 0.6304 | |
| SRP133303 | ZRANB2 | 9406 | RNAseq | -0.0064 | 0.9631 | |
| SRP159526 | ZRANB2 | 9406 | RNAseq | -0.4390 | 0.0218 | |
| SRP193095 | ZRANB2 | 9406 | RNAseq | -0.2314 | 0.0198 | |
| SRP219564 | ZRANB2 | 9406 | RNAseq | -0.0593 | 0.8578 | |
| TCGA | ZRANB2 | 9406 | RNAseq | -0.0176 | 0.7129 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZRANB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZRANB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZRANB2 | 9406 | 1 | 6 | 23 | |
| GSE20123 | ZRANB2 | 9406 | 1 | 6 | 23 | |
| GSE43470 | ZRANB2 | 9406 | 4 | 4 | 35 | |
| GSE46452 | ZRANB2 | 9406 | 0 | 1 | 58 | |
| GSE47630 | ZRANB2 | 9406 | 7 | 6 | 27 | |
| GSE54993 | ZRANB2 | 9406 | 0 | 1 | 69 | |
| GSE54994 | ZRANB2 | 9406 | 6 | 5 | 42 | |
| GSE60625 | ZRANB2 | 9406 | 0 | 0 | 11 | |
| GSE74703 | ZRANB2 | 9406 | 3 | 3 | 30 | |
| GSE74704 | ZRANB2 | 9406 | 1 | 3 | 16 | |
| TCGA | ZRANB2 | 9406 | 9 | 22 | 65 |
Total number of gains: 32; Total number of losses: 57; Total Number of normals: 399.
Somatic mutations of ZRANB2:
Generating mutation plots.
Highly correlated genes for ZRANB2:
Showing top 20/426 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZRANB2 | AKAP17A | 0.794535 | 3 | 0 | 3 |
| ZRANB2 | MACROD2 | 0.778051 | 3 | 0 | 3 |
| ZRANB2 | TOPORS | 0.765723 | 3 | 0 | 3 |
| ZRANB2 | RSAD1 | 0.758365 | 3 | 0 | 3 |
| ZRANB2 | VPS26A | 0.74535 | 3 | 0 | 3 |
| ZRANB2 | ZNF227 | 0.744179 | 3 | 0 | 3 |
| ZRANB2 | TM9SF3 | 0.740909 | 3 | 0 | 3 |
| ZRANB2 | PBX2 | 0.739269 | 3 | 0 | 3 |
| ZRANB2 | ZNF564 | 0.739103 | 3 | 0 | 3 |
| ZRANB2 | USP9Y | 0.738643 | 3 | 0 | 3 |
| ZRANB2 | MTRF1L | 0.733215 | 3 | 0 | 3 |
| ZRANB2 | MMRN2 | 0.730061 | 3 | 0 | 3 |
| ZRANB2 | MCPH1 | 0.729872 | 3 | 0 | 3 |
| ZRANB2 | THAP1 | 0.729252 | 3 | 0 | 3 |
| ZRANB2 | PANK1 | 0.728814 | 3 | 0 | 3 |
| ZRANB2 | CDK5RAP3 | 0.728307 | 3 | 0 | 3 |
| ZRANB2 | HNRNPA1 | 0.726137 | 4 | 0 | 3 |
| ZRANB2 | SYNE1 | 0.723033 | 3 | 0 | 3 |
| ZRANB2 | RDX | 0.717661 | 3 | 0 | 3 |
| ZRANB2 | XPO4 | 0.716437 | 3 | 0 | 3 |
For details and further investigation, click here
