| Full name: mitochondrial ribosomal protein S18C | Alias Symbol: MRPS18-1|CGI-134|FLJ11146|FLJ22967 | ||
| Type: protein-coding gene | Cytoband: 4q21.23 | ||
| Entrez ID: 51023 | HGNC ID: HGNC:16633 | Ensembl Gene: ENSG00000163319 | OMIM ID: 611983 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPS18C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS18C | 51023 | 228019_s_at | -0.1044 | 0.7850 | |
| GSE20347 | MRPS18C | 51023 | 220103_s_at | -0.0989 | 0.0763 | |
| GSE23400 | MRPS18C | 51023 | 220103_s_at | -0.0495 | 0.0226 | |
| GSE26886 | MRPS18C | 51023 | 228019_s_at | -0.8054 | 0.0000 | |
| GSE29001 | MRPS18C | 51023 | 220103_s_at | -0.2004 | 0.0446 | |
| GSE38129 | MRPS18C | 51023 | 220103_s_at | -0.1217 | 0.0121 | |
| GSE45670 | MRPS18C | 51023 | 228019_s_at | -0.1849 | 0.1036 | |
| GSE53622 | MRPS18C | 51023 | 31065 | -0.3462 | 0.0000 | |
| GSE53624 | MRPS18C | 51023 | 31065 | -0.2368 | 0.0002 | |
| GSE63941 | MRPS18C | 51023 | 228019_s_at | 0.5611 | 0.0532 | |
| GSE77861 | MRPS18C | 51023 | 228019_s_at | -0.7195 | 0.0785 | |
| GSE97050 | MRPS18C | 51023 | A_23_P81212 | -0.1910 | 0.5481 | |
| SRP007169 | MRPS18C | 51023 | RNAseq | -0.6480 | 0.1969 | |
| SRP064894 | MRPS18C | 51023 | RNAseq | -0.4743 | 0.0369 | |
| SRP133303 | MRPS18C | 51023 | RNAseq | -0.1304 | 0.4482 | |
| SRP159526 | MRPS18C | 51023 | RNAseq | -0.5583 | 0.0076 | |
| SRP193095 | MRPS18C | 51023 | RNAseq | -0.8649 | 0.0000 | |
| SRP219564 | MRPS18C | 51023 | RNAseq | -0.5199 | 0.0777 | |
| TCGA | MRPS18C | 51023 | RNAseq | -0.0405 | 0.5190 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS18C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS18C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS18C | 51023 | 2 | 11 | 17 | |
| GSE20123 | MRPS18C | 51023 | 2 | 11 | 17 | |
| GSE43470 | MRPS18C | 51023 | 0 | 13 | 30 | |
| GSE46452 | MRPS18C | 51023 | 1 | 36 | 22 | |
| GSE47630 | MRPS18C | 51023 | 0 | 20 | 20 | |
| GSE54993 | MRPS18C | 51023 | 8 | 0 | 62 | |
| GSE54994 | MRPS18C | 51023 | 1 | 9 | 43 | |
| GSE60625 | MRPS18C | 51023 | 0 | 0 | 11 | |
| GSE74703 | MRPS18C | 51023 | 0 | 11 | 25 | |
| GSE74704 | MRPS18C | 51023 | 1 | 6 | 13 | |
| TCGA | MRPS18C | 51023 | 11 | 34 | 51 |
Total number of gains: 26; Total number of losses: 151; Total Number of normals: 311.
Somatic mutations of MRPS18C:
Generating mutation plots.
Highly correlated genes for MRPS18C:
Showing top 20/984 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS18C | UBE2J1 | 0.867966 | 3 | 0 | 3 |
| MRPS18C | GBF1 | 0.813671 | 3 | 0 | 3 |
| MRPS18C | ATP6V1B2 | 0.789335 | 3 | 0 | 3 |
| MRPS18C | UNC5CL | 0.755956 | 3 | 0 | 3 |
| MRPS18C | RMND1 | 0.738922 | 3 | 0 | 3 |
| MRPS18C | FMO4 | 0.737664 | 3 | 0 | 3 |
| MRPS18C | IMPACT | 0.735608 | 3 | 0 | 3 |
| MRPS18C | RBM5 | 0.734722 | 3 | 0 | 3 |
| MRPS18C | PIH1D2 | 0.733191 | 3 | 0 | 3 |
| MRPS18C | TMEM234 | 0.731261 | 4 | 0 | 4 |
| MRPS18C | TP53RK | 0.726767 | 3 | 0 | 3 |
| MRPS18C | PSENEN | 0.722501 | 4 | 0 | 3 |
| MRPS18C | NDUFA11 | 0.721644 | 3 | 0 | 3 |
| MRPS18C | GRAP2 | 0.720093 | 3 | 0 | 3 |
| MRPS18C | STK38 | 0.717351 | 5 | 0 | 5 |
| MRPS18C | DECR1 | 0.713785 | 5 | 0 | 5 |
| MRPS18C | ZRANB1 | 0.710894 | 3 | 0 | 3 |
| MRPS18C | CCNYL1 | 0.704119 | 4 | 0 | 4 |
| MRPS18C | TMEM218 | 0.702179 | 3 | 0 | 3 |
| MRPS18C | TYSND1 | 0.70209 | 3 | 0 | 3 |
For details and further investigation, click here
