| Full name: NADH:ubiquinone oxidoreductase subunit A5 | Alias Symbol: B13|NUFM|CI-13KD-B|UQOR13|CI-13kB | ||
| Type: protein-coding gene | Cytoband: 7q31.32 | ||
| Entrez ID: 4698 | HGNC ID: HGNC:7688 | Ensembl Gene: ENSG00000128609 | OMIM ID: 601677 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFA5 | 4698 | 201304_at | -0.5211 | 0.3321 | |
| GSE20347 | NDUFA5 | 4698 | 201304_at | -0.1477 | 0.2710 | |
| GSE23400 | NDUFA5 | 4698 | 201304_at | -0.1492 | 0.2739 | |
| GSE26886 | NDUFA5 | 4698 | 201304_at | -0.4616 | 0.0310 | |
| GSE29001 | NDUFA5 | 4698 | 201304_at | 0.0113 | 0.9698 | |
| GSE38129 | NDUFA5 | 4698 | 201304_at | -0.3016 | 0.0244 | |
| GSE45670 | NDUFA5 | 4698 | 201304_at | -0.3577 | 0.0553 | |
| GSE53622 | NDUFA5 | 4698 | 74967 | -0.5215 | 0.0000 | |
| GSE53624 | NDUFA5 | 4698 | 74967 | -0.1412 | 0.0059 | |
| GSE63941 | NDUFA5 | 4698 | 201304_at | -0.7961 | 0.0769 | |
| GSE77861 | NDUFA5 | 4698 | 201304_at | -0.3566 | 0.2723 | |
| GSE97050 | NDUFA5 | 4698 | A_23_P215751 | -0.5953 | 0.2065 | |
| SRP007169 | NDUFA5 | 4698 | RNAseq | 0.6780 | 0.0840 | |
| SRP008496 | NDUFA5 | 4698 | RNAseq | 0.7562 | 0.0065 | |
| SRP064894 | NDUFA5 | 4698 | RNAseq | -0.1215 | 0.3015 | |
| SRP133303 | NDUFA5 | 4698 | RNAseq | 0.2265 | 0.1245 | |
| SRP159526 | NDUFA5 | 4698 | RNAseq | -0.3447 | 0.1997 | |
| SRP193095 | NDUFA5 | 4698 | RNAseq | -0.6118 | 0.0000 | |
| SRP219564 | NDUFA5 | 4698 | RNAseq | -0.5427 | 0.2229 | |
| TCGA | NDUFA5 | 4698 | RNAseq | -0.3041 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFA5 | 4698 | 6 | 2 | 22 | |
| GSE20123 | NDUFA5 | 4698 | 7 | 2 | 21 | |
| GSE43470 | NDUFA5 | 4698 | 2 | 4 | 37 | |
| GSE46452 | NDUFA5 | 4698 | 8 | 1 | 50 | |
| GSE47630 | NDUFA5 | 4698 | 7 | 4 | 29 | |
| GSE54993 | NDUFA5 | 4698 | 3 | 5 | 62 | |
| GSE54994 | NDUFA5 | 4698 | 9 | 7 | 37 | |
| GSE60625 | NDUFA5 | 4698 | 0 | 0 | 11 | |
| GSE74703 | NDUFA5 | 4698 | 2 | 4 | 30 | |
| GSE74704 | NDUFA5 | 4698 | 5 | 2 | 13 | |
| TCGA | NDUFA5 | 4698 | 27 | 21 | 48 |
Total number of gains: 76; Total number of losses: 52; Total Number of normals: 360.
Somatic mutations of NDUFA5:
Generating mutation plots.
Highly correlated genes for NDUFA5:
Showing top 20/756 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFA5 | NTN4 | 0.770905 | 3 | 0 | 3 |
| NDUFA5 | CFL2 | 0.767027 | 3 | 0 | 3 |
| NDUFA5 | C5orf24 | 0.761485 | 4 | 0 | 4 |
| NDUFA5 | KIAA1143 | 0.739434 | 5 | 0 | 5 |
| NDUFA5 | NDUFA12 | 0.736668 | 3 | 0 | 3 |
| NDUFA5 | FRA10AC1 | 0.729945 | 3 | 0 | 3 |
| NDUFA5 | UQCR11 | 0.725902 | 3 | 0 | 3 |
| NDUFA5 | SORCS1 | 0.718383 | 3 | 0 | 3 |
| NDUFA5 | ZRANB1 | 0.71184 | 3 | 0 | 3 |
| NDUFA5 | MYSM1 | 0.709207 | 3 | 0 | 3 |
| NDUFA5 | SLC25A26 | 0.708651 | 4 | 0 | 4 |
| NDUFA5 | TET2 | 0.704874 | 3 | 0 | 3 |
| NDUFA5 | ARL6 | 0.704165 | 5 | 0 | 4 |
| NDUFA5 | BTD | 0.704052 | 4 | 0 | 4 |
| NDUFA5 | RASSF3 | 0.70373 | 4 | 0 | 4 |
| NDUFA5 | DPY19L3 | 0.701425 | 3 | 0 | 3 |
| NDUFA5 | NKTR | 0.700593 | 3 | 0 | 3 |
| NDUFA5 | ZNF570 | 0.696557 | 5 | 0 | 4 |
| NDUFA5 | ZDHHC21 | 0.696384 | 3 | 0 | 3 |
| NDUFA5 | CAMTA1 | 0.695388 | 3 | 0 | 3 |
For details and further investigation, click here
