| Full name: netrin 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q22 | ||
| Entrez ID: 59277 | HGNC ID: HGNC:13658 | Ensembl Gene: ENSG00000074527 | OMIM ID: 610401 |
| Drug and gene relationship at DGIdb | |||
Expression of NTN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NTN4 | 59277 | 223315_at | -0.9432 | 0.2724 | |
| GSE26886 | NTN4 | 59277 | 223315_at | 1.2680 | 0.0579 | |
| GSE45670 | NTN4 | 59277 | 223315_at | -1.3491 | 0.0002 | |
| GSE53622 | NTN4 | 59277 | 173497 | -0.9833 | 0.0000 | |
| GSE53624 | NTN4 | 59277 | 173497 | -1.1274 | 0.0000 | |
| GSE63941 | NTN4 | 59277 | 223315_at | -1.0349 | 0.4609 | |
| GSE77861 | NTN4 | 59277 | 223315_at | 0.1873 | 0.6996 | |
| GSE97050 | NTN4 | 59277 | A_23_P204630 | -0.6753 | 0.1616 | |
| SRP007169 | NTN4 | 59277 | RNAseq | -0.1970 | 0.7722 | |
| SRP008496 | NTN4 | 59277 | RNAseq | -0.3519 | 0.4845 | |
| SRP064894 | NTN4 | 59277 | RNAseq | -0.5706 | 0.0630 | |
| SRP133303 | NTN4 | 59277 | RNAseq | -0.6070 | 0.0322 | |
| SRP159526 | NTN4 | 59277 | RNAseq | -0.8897 | 0.0009 | |
| SRP193095 | NTN4 | 59277 | RNAseq | -0.3024 | 0.3474 | |
| SRP219564 | NTN4 | 59277 | RNAseq | -0.9920 | 0.1532 | |
| TCGA | NTN4 | 59277 | RNAseq | -0.8030 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NTN4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NTN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NTN4 | 59277 | 3 | 2 | 25 | |
| GSE20123 | NTN4 | 59277 | 3 | 2 | 25 | |
| GSE43470 | NTN4 | 59277 | 3 | 0 | 40 | |
| GSE46452 | NTN4 | 59277 | 9 | 1 | 49 | |
| GSE47630 | NTN4 | 59277 | 9 | 1 | 30 | |
| GSE54993 | NTN4 | 59277 | 0 | 5 | 65 | |
| GSE54994 | NTN4 | 59277 | 4 | 1 | 48 | |
| GSE60625 | NTN4 | 59277 | 0 | 0 | 11 | |
| GSE74703 | NTN4 | 59277 | 3 | 0 | 33 | |
| GSE74704 | NTN4 | 59277 | 1 | 2 | 17 | |
| TCGA | NTN4 | 59277 | 18 | 10 | 68 |
Total number of gains: 53; Total number of losses: 24; Total Number of normals: 411.
Somatic mutations of NTN4:
Generating mutation plots.
Highly correlated genes for NTN4:
Showing top 20/844 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NTN4 | SYNC | 0.794071 | 3 | 0 | 3 |
| NTN4 | TIMP3 | 0.783306 | 3 | 0 | 3 |
| NTN4 | KCNB1 | 0.77972 | 4 | 0 | 4 |
| NTN4 | MAMDC2 | 0.777877 | 5 | 0 | 5 |
| NTN4 | SLIT3 | 0.7756 | 3 | 0 | 3 |
| NTN4 | NDUFA5 | 0.770905 | 3 | 0 | 3 |
| NTN4 | SORCS1 | 0.770346 | 4 | 0 | 4 |
| NTN4 | BBS1 | 0.763018 | 4 | 0 | 4 |
| NTN4 | PEG3 | 0.759105 | 3 | 0 | 3 |
| NTN4 | MYOCD | 0.757738 | 4 | 0 | 4 |
| NTN4 | ASPA | 0.753208 | 5 | 0 | 5 |
| NTN4 | EID3 | 0.751296 | 3 | 0 | 3 |
| NTN4 | FAM13C | 0.750606 | 3 | 0 | 3 |
| NTN4 | RNPC3 | 0.748029 | 3 | 0 | 3 |
| NTN4 | CNN1 | 0.74547 | 3 | 0 | 3 |
| NTN4 | TNFSF12 | 0.74518 | 3 | 0 | 3 |
| NTN4 | TCEAL6 | 0.744412 | 3 | 0 | 3 |
| NTN4 | CLEC3B | 0.73615 | 3 | 0 | 3 |
| NTN4 | FXYD1 | 0.735625 | 3 | 0 | 3 |
| NTN4 | ABCA8 | 0.734259 | 5 | 0 | 5 |
For details and further investigation, click here
