| Full name: ubiquinol-cytochrome c reductase, complex III subunit XI | Alias Symbol: QCR10 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 10975 | HGNC ID: HGNC:30862 | Ensembl Gene: ENSG00000127540 | OMIM ID: 609711 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UQCR11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UQCR11 | 10975 | 202090_s_at | -0.1480 | 0.5931 | |
| GSE20347 | UQCR11 | 10975 | 202090_s_at | -0.2949 | 0.0748 | |
| GSE23400 | UQCR11 | 10975 | 202090_s_at | -0.2538 | 0.0021 | |
| GSE26886 | UQCR11 | 10975 | 202090_s_at | 0.4603 | 0.0151 | |
| GSE29001 | UQCR11 | 10975 | 202090_s_at | -0.6373 | 0.0496 | |
| GSE38129 | UQCR11 | 10975 | 202090_s_at | -0.2686 | 0.0308 | |
| GSE45670 | UQCR11 | 10975 | 202090_s_at | -0.0851 | 0.5155 | |
| GSE53622 | UQCR11 | 10975 | 31217 | -0.6993 | 0.0000 | |
| GSE53624 | UQCR11 | 10975 | 31217 | -0.1325 | 0.0088 | |
| GSE63941 | UQCR11 | 10975 | 202090_s_at | -0.4188 | 0.1396 | |
| GSE77861 | UQCR11 | 10975 | 202090_s_at | -0.0806 | 0.7150 | |
| GSE97050 | UQCR11 | 10975 | A_23_P56314 | -0.3509 | 0.2119 | |
| SRP007169 | UQCR11 | 10975 | RNAseq | -1.2470 | 0.0002 | |
| SRP008496 | UQCR11 | 10975 | RNAseq | -1.0320 | 0.0000 | |
| SRP064894 | UQCR11 | 10975 | RNAseq | 0.1724 | 0.6367 | |
| SRP133303 | UQCR11 | 10975 | RNAseq | -0.2697 | 0.0851 | |
| SRP159526 | UQCR11 | 10975 | RNAseq | -0.3772 | 0.1428 | |
| SRP193095 | UQCR11 | 10975 | RNAseq | -0.7019 | 0.0000 | |
| SRP219564 | UQCR11 | 10975 | RNAseq | -0.4670 | 0.1952 | |
| TCGA | UQCR11 | 10975 | RNAseq | -0.1511 | 0.0040 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UQCR11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UQCR11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UQCR11 | 10975 | 4 | 6 | 20 | |
| GSE20123 | UQCR11 | 10975 | 4 | 5 | 21 | |
| GSE43470 | UQCR11 | 10975 | 1 | 11 | 31 | |
| GSE46452 | UQCR11 | 10975 | 47 | 1 | 11 | |
| GSE47630 | UQCR11 | 10975 | 5 | 7 | 28 | |
| GSE54993 | UQCR11 | 10975 | 16 | 3 | 51 | |
| GSE54994 | UQCR11 | 10975 | 8 | 15 | 30 | |
| GSE60625 | UQCR11 | 10975 | 9 | 0 | 2 | |
| GSE74703 | UQCR11 | 10975 | 1 | 8 | 27 | |
| GSE74704 | UQCR11 | 10975 | 3 | 3 | 14 | |
| TCGA | UQCR11 | 10975 | 6 | 25 | 65 |
Total number of gains: 104; Total number of losses: 84; Total Number of normals: 300.
Somatic mutations of UQCR11:
Generating mutation plots.
Highly correlated genes for UQCR11:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UQCR11 | UROS | 0.74389 | 3 | 0 | 3 |
| UQCR11 | IFT20 | 0.741248 | 3 | 0 | 3 |
| UQCR11 | SEC22B | 0.739673 | 3 | 0 | 3 |
| UQCR11 | AMD1 | 0.73576 | 3 | 0 | 3 |
| UQCR11 | NDUFA5 | 0.725902 | 3 | 0 | 3 |
| UQCR11 | BCLAF1 | 0.720962 | 3 | 0 | 3 |
| UQCR11 | CADM3 | 0.72066 | 3 | 0 | 3 |
| UQCR11 | RIMKLB | 0.719218 | 3 | 0 | 3 |
| UQCR11 | EPC1 | 0.719126 | 3 | 0 | 3 |
| UQCR11 | CHCHD1 | 0.716972 | 3 | 0 | 3 |
| UQCR11 | SLMAP | 0.714663 | 3 | 0 | 3 |
| UQCR11 | TAF11 | 0.713207 | 3 | 0 | 3 |
| UQCR11 | ALKBH7 | 0.710967 | 4 | 0 | 3 |
| UQCR11 | NME5 | 0.7056 | 3 | 0 | 3 |
| UQCR11 | GPR108 | 0.701912 | 3 | 0 | 3 |
| UQCR11 | PYROXD1 | 0.699442 | 5 | 0 | 5 |
| UQCR11 | LIMD2 | 0.697158 | 3 | 0 | 3 |
| UQCR11 | NSMCE4A | 0.696758 | 3 | 0 | 3 |
| UQCR11 | YPEL2 | 0.695828 | 3 | 0 | 3 |
| UQCR11 | DGCR2 | 0.689624 | 3 | 0 | 3 |
For details and further investigation, click here
