| Full name: biotinidase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 686 | HGNC ID: HGNC:1122 | Ensembl Gene: ENSG00000169814 | OMIM ID: 609019 |
| Drug and gene relationship at DGIdb | |||
Expression of BTD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTD | 686 | 204167_at | -0.3909 | 0.1241 | |
| GSE20347 | BTD | 686 | 214116_at | -0.5202 | 0.0000 | |
| GSE23400 | BTD | 686 | 214116_at | -0.1939 | 0.0000 | |
| GSE26886 | BTD | 686 | 204167_at | -1.2200 | 0.0000 | |
| GSE29001 | BTD | 686 | 204167_at | -0.7476 | 0.0002 | |
| GSE38129 | BTD | 686 | 214116_at | -0.5311 | 0.0000 | |
| GSE45670 | BTD | 686 | 204167_at | -0.4118 | 0.0260 | |
| GSE53622 | BTD | 686 | 36309 | -1.0282 | 0.0000 | |
| GSE53624 | BTD | 686 | 36309 | -1.1097 | 0.0000 | |
| GSE63941 | BTD | 686 | 204167_at | -0.8630 | 0.1311 | |
| GSE77861 | BTD | 686 | 214116_at | -0.4785 | 0.0497 | |
| GSE97050 | BTD | 686 | A_23_P155351 | -0.4485 | 0.2460 | |
| SRP007169 | BTD | 686 | RNAseq | -1.6314 | 0.0000 | |
| SRP008496 | BTD | 686 | RNAseq | -0.9760 | 0.0227 | |
| SRP064894 | BTD | 686 | RNAseq | 0.0628 | 0.7670 | |
| SRP133303 | BTD | 686 | RNAseq | -0.5554 | 0.0006 | |
| SRP159526 | BTD | 686 | RNAseq | -0.8355 | 0.0467 | |
| SRP193095 | BTD | 686 | RNAseq | -0.9660 | 0.0000 | |
| SRP219564 | BTD | 686 | RNAseq | -0.4591 | 0.2268 | |
| TCGA | BTD | 686 | RNAseq | -0.7102 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by BTD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTD | 686 | 2 | 19 | 9 | |
| GSE20123 | BTD | 686 | 2 | 19 | 9 | |
| GSE43470 | BTD | 686 | 0 | 21 | 22 | |
| GSE46452 | BTD | 686 | 2 | 17 | 40 | |
| GSE47630 | BTD | 686 | 2 | 23 | 15 | |
| GSE54993 | BTD | 686 | 6 | 1 | 63 | |
| GSE54994 | BTD | 686 | 1 | 32 | 20 | |
| GSE60625 | BTD | 686 | 5 | 0 | 6 | |
| GSE74703 | BTD | 686 | 0 | 17 | 19 | |
| GSE74704 | BTD | 686 | 1 | 13 | 6 | |
| TCGA | BTD | 686 | 2 | 68 | 26 |
Total number of gains: 23; Total number of losses: 230; Total Number of normals: 235.
Somatic mutations of BTD:
Generating mutation plots.
Highly correlated genes for BTD:
Showing top 20/1526 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTD | CNST | 0.769755 | 3 | 0 | 3 |
| BTD | ANO5 | 0.7587 | 4 | 0 | 4 |
| BTD | ITPR1 | 0.757949 | 5 | 0 | 5 |
| BTD | DLD | 0.756436 | 3 | 0 | 3 |
| BTD | ZNF540 | 0.751555 | 3 | 0 | 3 |
| BTD | TAGAP | 0.749622 | 3 | 0 | 3 |
| BTD | SLMAP | 0.748328 | 6 | 0 | 6 |
| BTD | ULK3 | 0.746488 | 3 | 0 | 3 |
| BTD | KPNA3 | 0.740381 | 4 | 0 | 3 |
| BTD | CLEC3B | 0.738935 | 3 | 0 | 3 |
| BTD | KBTBD3 | 0.738826 | 4 | 0 | 4 |
| BTD | PPARGC1A | 0.737756 | 3 | 0 | 3 |
| BTD | GPRASP2 | 0.735761 | 3 | 0 | 3 |
| BTD | AP3S2 | 0.734822 | 3 | 0 | 3 |
| BTD | DNAJC15 | 0.723946 | 3 | 0 | 3 |
| BTD | CAP2 | 0.723691 | 3 | 0 | 3 |
| BTD | TNFSF12 | 0.721732 | 3 | 0 | 3 |
| BTD | FIBIN | 0.718474 | 4 | 0 | 3 |
| BTD | DNAJB14 | 0.718062 | 4 | 0 | 4 |
| BTD | RYR3 | 0.713164 | 4 | 0 | 4 |
For details and further investigation, click here
