| Full name: ADP ribosylation factor like GTPase 6 | Alias Symbol: RP55 | ||
| Type: protein-coding gene | Cytoband: 3q11.2 | ||
| Entrez ID: 84100 | HGNC ID: HGNC:13210 | Ensembl Gene: ENSG00000113966 | OMIM ID: 608845 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL6 | 84100 | 235320_at | -0.2319 | 0.7760 | |
| GSE26886 | ARL6 | 84100 | 235320_at | -0.9608 | 0.0144 | |
| GSE45670 | ARL6 | 84100 | 235320_at | -0.2738 | 0.0831 | |
| GSE53622 | ARL6 | 84100 | 9040 | -0.0317 | 0.7535 | |
| GSE53624 | ARL6 | 84100 | 24805 | -0.2257 | 0.0207 | |
| GSE63941 | ARL6 | 84100 | 223735_at | 0.4755 | 0.4049 | |
| GSE77861 | ARL6 | 84100 | 235320_at | -0.1532 | 0.4361 | |
| GSE97050 | ARL6 | 84100 | A_24_P354337 | 0.5432 | 0.1126 | |
| SRP007169 | ARL6 | 84100 | RNAseq | 0.5837 | 0.2845 | |
| SRP008496 | ARL6 | 84100 | RNAseq | 0.5101 | 0.1940 | |
| SRP064894 | ARL6 | 84100 | RNAseq | 0.2092 | 0.1865 | |
| SRP133303 | ARL6 | 84100 | RNAseq | 0.1347 | 0.5315 | |
| SRP159526 | ARL6 | 84100 | RNAseq | 0.2104 | 0.3444 | |
| SRP193095 | ARL6 | 84100 | RNAseq | -0.0936 | 0.5133 | |
| SRP219564 | ARL6 | 84100 | RNAseq | -0.1147 | 0.7474 | |
| TCGA | ARL6 | 84100 | RNAseq | -0.0475 | 0.6786 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL6 | 84100 | 20 | 1 | 9 | |
| GSE20123 | ARL6 | 84100 | 19 | 1 | 10 | |
| GSE43470 | ARL6 | 84100 | 18 | 1 | 24 | |
| GSE46452 | ARL6 | 84100 | 12 | 7 | 40 | |
| GSE47630 | ARL6 | 84100 | 16 | 6 | 18 | |
| GSE54993 | ARL6 | 84100 | 2 | 6 | 62 | |
| GSE54994 | ARL6 | 84100 | 27 | 5 | 21 | |
| GSE60625 | ARL6 | 84100 | 0 | 6 | 5 | |
| GSE74703 | ARL6 | 84100 | 14 | 1 | 21 | |
| GSE74704 | ARL6 | 84100 | 14 | 1 | 5 | |
| TCGA | ARL6 | 84100 | 50 | 11 | 35 |
Total number of gains: 192; Total number of losses: 46; Total Number of normals: 250.
Somatic mutations of ARL6:
Generating mutation plots.
Highly correlated genes for ARL6:
Showing top 20/400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL6 | BIVM | 0.807041 | 3 | 0 | 3 |
| ARL6 | ZNF564 | 0.790257 | 3 | 0 | 3 |
| ARL6 | KPNA3 | 0.77583 | 3 | 0 | 3 |
| ARL6 | ZNF394 | 0.774701 | 3 | 0 | 3 |
| ARL6 | BECN1 | 0.774442 | 3 | 0 | 3 |
| ARL6 | MFN1 | 0.774164 | 3 | 0 | 3 |
| ARL6 | ATP11B | 0.767544 | 3 | 0 | 3 |
| ARL6 | SCAF8 | 0.764861 | 3 | 0 | 3 |
| ARL6 | ARID2 | 0.764209 | 3 | 0 | 3 |
| ARL6 | ATG4C | 0.751792 | 3 | 0 | 3 |
| ARL6 | TET2 | 0.751434 | 3 | 0 | 3 |
| ARL6 | NAA35 | 0.745942 | 3 | 0 | 3 |
| ARL6 | CEP63 | 0.739821 | 3 | 0 | 3 |
| ARL6 | SP1 | 0.738271 | 3 | 0 | 3 |
| ARL6 | SMARCAD1 | 0.737888 | 3 | 0 | 3 |
| ARL6 | PIK3CB | 0.736734 | 4 | 0 | 4 |
| ARL6 | BTAF1 | 0.734357 | 3 | 0 | 3 |
| ARL6 | PEPD | 0.725801 | 3 | 0 | 3 |
| ARL6 | PHF2 | 0.724958 | 3 | 0 | 3 |
| ARL6 | GTF2A1 | 0.721259 | 3 | 0 | 3 |
For details and further investigation, click here
