| Full name: NADH:ubiquinone oxidoreductase subunit B6 | Alias Symbol: B17|CI | ||
| Type: protein-coding gene | Cytoband: 9p21.1 | ||
| Entrez ID: 4712 | HGNC ID: HGNC:7701 | Ensembl Gene: ENSG00000165264 | OMIM ID: 603322 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFB6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFB6 | 4712 | 203613_s_at | -0.2749 | 0.3977 | |
| GSE20347 | NDUFB6 | 4712 | 203613_s_at | -0.3283 | 0.0139 | |
| GSE23400 | NDUFB6 | 4712 | 203613_s_at | 0.0830 | 0.2909 | |
| GSE26886 | NDUFB6 | 4712 | 203613_s_at | 0.2427 | 0.1178 | |
| GSE29001 | NDUFB6 | 4712 | 203613_s_at | -0.0940 | 0.7669 | |
| GSE38129 | NDUFB6 | 4712 | 203613_s_at | -0.1756 | 0.1133 | |
| GSE45670 | NDUFB6 | 4712 | 203613_s_at | -0.0240 | 0.8734 | |
| GSE53622 | NDUFB6 | 4712 | 62997 | -0.2522 | 0.0015 | |
| GSE53624 | NDUFB6 | 4712 | 62997 | -0.0393 | 0.7395 | |
| GSE63941 | NDUFB6 | 4712 | 203613_s_at | 0.1166 | 0.8062 | |
| GSE77861 | NDUFB6 | 4712 | 203613_s_at | -0.1037 | 0.8553 | |
| GSE97050 | NDUFB6 | 4712 | A_23_P43613 | -0.0337 | 0.9022 | |
| SRP007169 | NDUFB6 | 4712 | RNAseq | 1.8771 | 0.0089 | |
| SRP008496 | NDUFB6 | 4712 | RNAseq | 2.1070 | 0.0002 | |
| SRP064894 | NDUFB6 | 4712 | RNAseq | 0.1674 | 0.5306 | |
| SRP133303 | NDUFB6 | 4712 | RNAseq | -0.0457 | 0.7461 | |
| SRP159526 | NDUFB6 | 4712 | RNAseq | -0.3318 | 0.3333 | |
| SRP193095 | NDUFB6 | 4712 | RNAseq | -0.7393 | 0.0000 | |
| SRP219564 | NDUFB6 | 4712 | RNAseq | -0.5728 | 0.0975 | |
| TCGA | NDUFB6 | 4712 | RNAseq | -0.0406 | 0.5044 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NDUFB6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFB6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFB6 | 4712 | 2 | 15 | 13 | |
| GSE20123 | NDUFB6 | 4712 | 2 | 15 | 13 | |
| GSE43470 | NDUFB6 | 4712 | 4 | 9 | 30 | |
| GSE46452 | NDUFB6 | 4712 | 6 | 17 | 36 | |
| GSE47630 | NDUFB6 | 4712 | 1 | 21 | 18 | |
| GSE54993 | NDUFB6 | 4712 | 6 | 0 | 64 | |
| GSE54994 | NDUFB6 | 4712 | 7 | 11 | 35 | |
| GSE60625 | NDUFB6 | 4712 | 0 | 0 | 11 | |
| GSE74703 | NDUFB6 | 4712 | 3 | 7 | 26 | |
| GSE74704 | NDUFB6 | 4712 | 0 | 11 | 9 | |
| TCGA | NDUFB6 | 4712 | 16 | 44 | 36 |
Total number of gains: 47; Total number of losses: 150; Total Number of normals: 291.
Somatic mutations of NDUFB6:
Generating mutation plots.
Highly correlated genes for NDUFB6:
Showing top 20/284 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFB6 | NTAN1 | 0.803955 | 3 | 0 | 3 |
| NDUFB6 | EIF1AY | 0.750402 | 3 | 0 | 3 |
| NDUFB6 | MGMT | 0.734315 | 3 | 0 | 3 |
| NDUFB6 | NDUFA9 | 0.730642 | 4 | 0 | 4 |
| NDUFB6 | ELP3 | 0.722146 | 3 | 0 | 3 |
| NDUFB6 | SEC22B | 0.72168 | 4 | 0 | 3 |
| NDUFB6 | SLC38A5 | 0.714071 | 3 | 0 | 3 |
| NDUFB6 | MRPS35 | 0.712631 | 3 | 0 | 3 |
| NDUFB6 | PPIL3 | 0.70524 | 3 | 0 | 3 |
| NDUFB6 | ZNF619 | 0.704989 | 3 | 0 | 3 |
| NDUFB6 | SLC10A7 | 0.701443 | 3 | 0 | 3 |
| NDUFB6 | PPID | 0.70022 | 4 | 0 | 3 |
| NDUFB6 | VPS29 | 0.696064 | 5 | 0 | 4 |
| NDUFB6 | MCMBP | 0.695855 | 4 | 0 | 4 |
| NDUFB6 | CD164 | 0.694748 | 3 | 0 | 3 |
| NDUFB6 | CEP44 | 0.694062 | 4 | 0 | 3 |
| NDUFB6 | CREG1 | 0.691709 | 3 | 0 | 3 |
| NDUFB6 | CDKN1B | 0.69021 | 3 | 0 | 3 |
| NDUFB6 | CHMP4B | 0.685979 | 4 | 0 | 3 |
| NDUFB6 | UBR2 | 0.684787 | 4 | 0 | 4 |
For details and further investigation, click here
