| Full name: SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) | Alias Symbol: sec22b|ERS-24 | ||
| Type: protein-coding gene | Cytoband: 1p12 | ||
| Entrez ID: 9554 | HGNC ID: HGNC:10700 | Ensembl Gene: ENSG00000265808 | OMIM ID: 604029 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC22B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC22B | 9554 | 214257_s_at | -0.7531 | 0.0726 | |
| GSE20347 | SEC22B | 9554 | 214257_s_at | -0.2292 | 0.0772 | |
| GSE23400 | SEC22B | 9554 | 214257_s_at | -0.1079 | 0.2183 | |
| GSE26886 | SEC22B | 9554 | 214257_s_at | -0.2740 | 0.3706 | |
| GSE29001 | SEC22B | 9554 | 214257_s_at | -0.4429 | 0.3549 | |
| GSE38129 | SEC22B | 9554 | 214257_s_at | -0.2109 | 0.5220 | |
| GSE45670 | SEC22B | 9554 | 214257_s_at | -0.3171 | 0.1264 | |
| GSE53622 | SEC22B | 9554 | 16217 | -0.1288 | 0.0549 | |
| GSE53624 | SEC22B | 9554 | 16217 | -0.0716 | 0.1935 | |
| GSE63941 | SEC22B | 9554 | 214257_s_at | 0.6955 | 0.1323 | |
| GSE77861 | SEC22B | 9554 | 214257_s_at | -0.3508 | 0.5190 | |
| GSE97050 | SEC22B | 9554 | A_23_P412392 | 0.0327 | 0.9027 | |
| SRP007169 | SEC22B | 9554 | RNAseq | -0.2985 | 0.3718 | |
| SRP008496 | SEC22B | 9554 | RNAseq | 0.0057 | 0.9817 | |
| SRP064894 | SEC22B | 9554 | RNAseq | 0.0384 | 0.7944 | |
| SRP133303 | SEC22B | 9554 | RNAseq | 0.0908 | 0.5857 | |
| SRP159526 | SEC22B | 9554 | RNAseq | -0.1789 | 0.5808 | |
| SRP193095 | SEC22B | 9554 | RNAseq | -0.1940 | 0.1908 | |
| SRP219564 | SEC22B | 9554 | RNAseq | 0.1918 | 0.6321 | |
| TCGA | SEC22B | 9554 | RNAseq | -0.2178 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SEC22B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC22B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC22B | 9554 | 12 | 1 | 17 | |
| GSE20123 | SEC22B | 9554 | 11 | 2 | 17 | |
| GSE43470 | SEC22B | 9554 | 4 | 2 | 37 | |
| GSE46452 | SEC22B | 9554 | 2 | 1 | 56 | |
| GSE47630 | SEC22B | 9554 | 12 | 2 | 26 | |
| GSE54993 | SEC22B | 9554 | 0 | 2 | 68 | |
| GSE54994 | SEC22B | 9554 | 15 | 0 | 38 | |
| GSE60625 | SEC22B | 9554 | 0 | 0 | 11 | |
| GSE74703 | SEC22B | 9554 | 4 | 2 | 30 | |
| GSE74704 | SEC22B | 9554 | 6 | 1 | 13 | |
| TCGA | SEC22B | 9554 | 33 | 15 | 48 |
Total number of gains: 99; Total number of losses: 28; Total Number of normals: 361.
Somatic mutations of SEC22B:
Generating mutation plots.
Highly correlated genes for SEC22B:
Showing top 20/257 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC22B | EIF1AY | 0.785381 | 3 | 0 | 3 |
| SEC22B | KDM5D | 0.76587 | 3 | 0 | 3 |
| SEC22B | TMEM50A | 0.764439 | 3 | 0 | 3 |
| SEC22B | NDUFV2 | 0.759499 | 3 | 0 | 3 |
| SEC22B | MOB4 | 0.756405 | 4 | 0 | 3 |
| SEC22B | DLD | 0.753246 | 3 | 0 | 3 |
| SEC22B | UFC1 | 0.75193 | 3 | 0 | 3 |
| SEC22B | ZNF136 | 0.740691 | 3 | 0 | 3 |
| SEC22B | UQCR11 | 0.739673 | 3 | 0 | 3 |
| SEC22B | NDUFB6 | 0.72168 | 4 | 0 | 3 |
| SEC22B | OR7A10 | 0.721009 | 3 | 0 | 3 |
| SEC22B | UGCG | 0.719752 | 3 | 0 | 3 |
| SEC22B | NOA1 | 0.719418 | 3 | 0 | 3 |
| SEC22B | CD99 | 0.717521 | 3 | 0 | 3 |
| SEC22B | ADAM11 | 0.716875 | 3 | 0 | 3 |
| SEC22B | ZNF33A | 0.711748 | 3 | 0 | 3 |
| SEC22B | PPP1R11 | 0.709523 | 3 | 0 | 3 |
| SEC22B | RB1CC1 | 0.707262 | 3 | 0 | 3 |
| SEC22B | SGMS1 | 0.701316 | 3 | 0 | 3 |
| SEC22B | ADH1C | 0.695858 | 3 | 0 | 3 |
For details and further investigation, click here
