| Full name: elongator acetyltransferase complex subunit 3 | Alias Symbol: FLJ10422|KAT9 | ||
| Type: protein-coding gene | Cytoband: 8p21.1 | ||
| Entrez ID: 55140 | HGNC ID: HGNC:20696 | Ensembl Gene: ENSG00000134014 | OMIM ID: 612722 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ELP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELP3 | 55140 | 227075_at | -0.1729 | 0.7449 | |
| GSE20347 | ELP3 | 55140 | 221094_s_at | 0.3330 | 0.0020 | |
| GSE23400 | ELP3 | 55140 | 221094_s_at | 0.2032 | 0.0001 | |
| GSE26886 | ELP3 | 55140 | 227075_at | 0.4783 | 0.1451 | |
| GSE29001 | ELP3 | 55140 | 221094_s_at | 0.4755 | 0.1081 | |
| GSE38129 | ELP3 | 55140 | 221094_s_at | 0.2476 | 0.0555 | |
| GSE45670 | ELP3 | 55140 | 227075_at | -0.0529 | 0.8105 | |
| GSE53622 | ELP3 | 55140 | 17215 | 0.0161 | 0.8518 | |
| GSE53624 | ELP3 | 55140 | 17215 | 0.2976 | 0.0000 | |
| GSE63941 | ELP3 | 55140 | 221094_s_at | 1.0792 | 0.0037 | |
| GSE77861 | ELP3 | 55140 | 221094_s_at | 0.2407 | 0.0501 | |
| GSE97050 | ELP3 | 55140 | A_23_P43034 | -0.0539 | 0.8312 | |
| SRP007169 | ELP3 | 55140 | RNAseq | 0.6599 | 0.1572 | |
| SRP008496 | ELP3 | 55140 | RNAseq | 0.3596 | 0.3014 | |
| SRP064894 | ELP3 | 55140 | RNAseq | 0.3025 | 0.0514 | |
| SRP133303 | ELP3 | 55140 | RNAseq | -0.2398 | 0.2187 | |
| SRP159526 | ELP3 | 55140 | RNAseq | -0.1800 | 0.4989 | |
| SRP193095 | ELP3 | 55140 | RNAseq | -0.0040 | 0.9728 | |
| SRP219564 | ELP3 | 55140 | RNAseq | 0.0257 | 0.9350 | |
| TCGA | ELP3 | 55140 | RNAseq | -0.0297 | 0.6067 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ELP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELP3 | 55140 | 4 | 10 | 16 | |
| GSE20123 | ELP3 | 55140 | 4 | 10 | 16 | |
| GSE43470 | ELP3 | 55140 | 4 | 7 | 32 | |
| GSE46452 | ELP3 | 55140 | 13 | 13 | 33 | |
| GSE47630 | ELP3 | 55140 | 10 | 8 | 22 | |
| GSE54993 | ELP3 | 55140 | 2 | 15 | 53 | |
| GSE54994 | ELP3 | 55140 | 10 | 15 | 28 | |
| GSE60625 | ELP3 | 55140 | 3 | 0 | 8 | |
| GSE74703 | ELP3 | 55140 | 4 | 6 | 26 | |
| GSE74704 | ELP3 | 55140 | 3 | 7 | 10 | |
| TCGA | ELP3 | 55140 | 17 | 42 | 37 |
Total number of gains: 74; Total number of losses: 133; Total Number of normals: 281.
Somatic mutations of ELP3:
Generating mutation plots.
Highly correlated genes for ELP3:
Showing top 20/677 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELP3 | RPUSD3 | 0.822959 | 3 | 0 | 3 |
| ELP3 | TCEANC2 | 0.779803 | 3 | 0 | 3 |
| ELP3 | R3HDM2 | 0.774861 | 3 | 0 | 3 |
| ELP3 | DNMBP | 0.763227 | 3 | 0 | 3 |
| ELP3 | C1orf50 | 0.757437 | 3 | 0 | 3 |
| ELP3 | MRPL38 | 0.756 | 3 | 0 | 3 |
| ELP3 | ALDOC | 0.741564 | 3 | 0 | 3 |
| ELP3 | PRPF38A | 0.736972 | 3 | 0 | 3 |
| ELP3 | SEC22A | 0.727725 | 4 | 0 | 4 |
| ELP3 | IAH1 | 0.723888 | 4 | 0 | 4 |
| ELP3 | NDUFB6 | 0.722146 | 3 | 0 | 3 |
| ELP3 | IRF2BPL | 0.720452 | 3 | 0 | 3 |
| ELP3 | UTP23 | 0.718761 | 4 | 0 | 3 |
| ELP3 | FAM86C1 | 0.715114 | 3 | 0 | 3 |
| ELP3 | RPL41 | 0.71475 | 3 | 0 | 3 |
| ELP3 | LRIG3 | 0.714539 | 3 | 0 | 3 |
| ELP3 | SKA2 | 0.709419 | 3 | 0 | 3 |
| ELP3 | RPL37A | 0.706927 | 3 | 0 | 3 |
| ELP3 | ARPP19 | 0.703956 | 4 | 0 | 4 |
| ELP3 | MITD1 | 0.702104 | 3 | 0 | 3 |
For details and further investigation, click here
