| Full name: VPS29 retromer complex component | Alias Symbol: PEP11|DC7|DC15 | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 51699 | HGNC ID: HGNC:14340 | Ensembl Gene: ENSG00000111237 | OMIM ID: 606932 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of VPS29:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS29 | 51699 | 223026_s_at | -0.4139 | 0.1858 | |
| GSE26886 | VPS29 | 51699 | 223026_s_at | -0.4816 | 0.0027 | |
| GSE45670 | VPS29 | 51699 | 223026_s_at | -0.2112 | 0.0109 | |
| GSE53622 | VPS29 | 51699 | 101607 | -0.2397 | 0.0000 | |
| GSE53624 | VPS29 | 51699 | 101607 | -0.2383 | 0.0012 | |
| GSE63941 | VPS29 | 51699 | 223026_s_at | 0.4411 | 0.1204 | |
| GSE77861 | VPS29 | 51699 | 223026_s_at | -0.2044 | 0.3063 | |
| GSE97050 | VPS29 | 51699 | A_24_P175989 | -0.2162 | 0.4169 | |
| SRP007169 | VPS29 | 51699 | RNAseq | -0.7290 | 0.0271 | |
| SRP008496 | VPS29 | 51699 | RNAseq | -0.8338 | 0.0000 | |
| SRP064894 | VPS29 | 51699 | RNAseq | -0.4591 | 0.0003 | |
| SRP133303 | VPS29 | 51699 | RNAseq | 0.0779 | 0.6586 | |
| SRP159526 | VPS29 | 51699 | RNAseq | -0.4533 | 0.0458 | |
| SRP193095 | VPS29 | 51699 | RNAseq | -0.6281 | 0.0000 | |
| SRP219564 | VPS29 | 51699 | RNAseq | -0.7059 | 0.0020 | |
| TCGA | VPS29 | 51699 | RNAseq | 0.0135 | 0.7834 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VPS29 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS29:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS29 | 51699 | 5 | 3 | 22 | |
| GSE20123 | VPS29 | 51699 | 5 | 3 | 22 | |
| GSE43470 | VPS29 | 51699 | 2 | 1 | 40 | |
| GSE46452 | VPS29 | 51699 | 9 | 1 | 49 | |
| GSE47630 | VPS29 | 51699 | 9 | 3 | 28 | |
| GSE54993 | VPS29 | 51699 | 0 | 5 | 65 | |
| GSE54994 | VPS29 | 51699 | 4 | 3 | 46 | |
| GSE60625 | VPS29 | 51699 | 0 | 0 | 11 | |
| GSE74703 | VPS29 | 51699 | 2 | 0 | 34 | |
| GSE74704 | VPS29 | 51699 | 2 | 2 | 16 | |
| TCGA | VPS29 | 51699 | 22 | 10 | 64 |
Total number of gains: 60; Total number of losses: 31; Total Number of normals: 397.
Somatic mutations of VPS29:
Generating mutation plots.
Highly correlated genes for VPS29:
Showing top 20/928 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS29 | KIAA1191 | 0.823666 | 3 | 0 | 3 |
| VPS29 | ACRBP | 0.801283 | 3 | 0 | 3 |
| VPS29 | UBQLN1 | 0.793407 | 3 | 0 | 3 |
| VPS29 | FBXW2 | 0.78219 | 3 | 0 | 3 |
| VPS29 | RNASEL | 0.781006 | 3 | 0 | 3 |
| VPS29 | TMCC1 | 0.771213 | 3 | 0 | 3 |
| VPS29 | ZMPSTE24 | 0.767957 | 3 | 0 | 3 |
| VPS29 | RSL24D1 | 0.758124 | 4 | 0 | 4 |
| VPS29 | TAOK3 | 0.753904 | 3 | 0 | 3 |
| VPS29 | G3BP2 | 0.751439 | 3 | 0 | 3 |
| VPS29 | LANCL1 | 0.748966 | 4 | 0 | 4 |
| VPS29 | CRYZ | 0.737669 | 4 | 0 | 3 |
| VPS29 | TMEM59 | 0.736095 | 5 | 0 | 4 |
| VPS29 | TMEM43 | 0.735959 | 4 | 0 | 4 |
| VPS29 | C11orf54 | 0.732988 | 4 | 0 | 4 |
| VPS29 | DECR1 | 0.730282 | 5 | 0 | 5 |
| VPS29 | ACAA1 | 0.730158 | 3 | 0 | 3 |
| VPS29 | TMEM30A | 0.729776 | 3 | 0 | 3 |
| VPS29 | UBE2J1 | 0.729345 | 5 | 0 | 4 |
| VPS29 | MAP4K5 | 0.728876 | 3 | 0 | 3 |
For details and further investigation, click here
