| Full name: solute carrier family 10 member 7 | Alias Symbol: MGC25043|DKFZp566M114|DKFZp313H0531|DKFZp779O2438 | ||
| Type: protein-coding gene | Cytoband: 4q31.22 | ||
| Entrez ID: 84068 | HGNC ID: HGNC:23088 | Ensembl Gene: ENSG00000120519 | OMIM ID: 611459 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC10A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC10A7 | 84068 | 235143_at | -0.1643 | 0.7134 | |
| GSE26886 | SLC10A7 | 84068 | 235143_at | -0.9384 | 0.0001 | |
| GSE45670 | SLC10A7 | 84068 | 235143_at | 0.0119 | 0.9472 | |
| GSE53622 | SLC10A7 | 84068 | 92404 | -0.1952 | 0.0213 | |
| GSE53624 | SLC10A7 | 84068 | 92404 | -0.4239 | 0.0001 | |
| GSE63941 | SLC10A7 | 84068 | 235143_at | -0.3201 | 0.5381 | |
| GSE77861 | SLC10A7 | 84068 | 235143_at | -0.1363 | 0.3211 | |
| GSE97050 | SLC10A7 | 84068 | A_23_P213085 | 0.3794 | 0.2429 | |
| SRP007169 | SLC10A7 | 84068 | RNAseq | -0.7031 | 0.1431 | |
| SRP008496 | SLC10A7 | 84068 | RNAseq | -0.6913 | 0.0084 | |
| SRP064894 | SLC10A7 | 84068 | RNAseq | -0.3062 | 0.1870 | |
| SRP133303 | SLC10A7 | 84068 | RNAseq | 0.3630 | 0.0419 | |
| SRP159526 | SLC10A7 | 84068 | RNAseq | -0.6072 | 0.0191 | |
| SRP193095 | SLC10A7 | 84068 | RNAseq | -0.4399 | 0.0002 | |
| SRP219564 | SLC10A7 | 84068 | RNAseq | -0.1994 | 0.6508 | |
| TCGA | SLC10A7 | 84068 | RNAseq | -0.1688 | 0.0135 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC10A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC10A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC10A7 | 84068 | 0 | 12 | 18 | |
| GSE20123 | SLC10A7 | 84068 | 0 | 12 | 18 | |
| GSE43470 | SLC10A7 | 84068 | 0 | 13 | 30 | |
| GSE46452 | SLC10A7 | 84068 | 1 | 36 | 22 | |
| GSE47630 | SLC10A7 | 84068 | 0 | 22 | 18 | |
| GSE54993 | SLC10A7 | 84068 | 10 | 0 | 60 | |
| GSE54994 | SLC10A7 | 84068 | 2 | 11 | 40 | |
| GSE60625 | SLC10A7 | 84068 | 0 | 1 | 10 | |
| GSE74703 | SLC10A7 | 84068 | 0 | 11 | 25 | |
| GSE74704 | SLC10A7 | 84068 | 0 | 7 | 13 | |
| TCGA | SLC10A7 | 84068 | 12 | 32 | 52 |
Total number of gains: 25; Total number of losses: 157; Total Number of normals: 306.
Somatic mutations of SLC10A7:
Generating mutation plots.
Highly correlated genes for SLC10A7:
Showing top 20/780 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC10A7 | VPS53 | 0.781375 | 3 | 0 | 3 |
| SLC10A7 | PDIK1L | 0.779693 | 3 | 0 | 3 |
| SLC10A7 | GSTO2 | 0.777702 | 3 | 0 | 3 |
| SLC10A7 | MAP4K5 | 0.775027 | 3 | 0 | 3 |
| SLC10A7 | CHMP5 | 0.771245 | 3 | 0 | 3 |
| SLC10A7 | MON2 | 0.770524 | 3 | 0 | 3 |
| SLC10A7 | GAPVD1 | 0.765189 | 3 | 0 | 3 |
| SLC10A7 | MRPS27 | 0.762475 | 3 | 0 | 3 |
| SLC10A7 | DALRD3 | 0.761736 | 3 | 0 | 3 |
| SLC10A7 | B4GALT5 | 0.758271 | 4 | 0 | 4 |
| SLC10A7 | SNRNP35 | 0.757073 | 3 | 0 | 3 |
| SLC10A7 | THG1L | 0.755985 | 3 | 0 | 3 |
| SLC10A7 | TMEM167A | 0.75453 | 3 | 0 | 3 |
| SLC10A7 | OSBPL2 | 0.753943 | 4 | 0 | 4 |
| SLC10A7 | RCOR1 | 0.752857 | 4 | 0 | 3 |
| SLC10A7 | CCDC25 | 0.746259 | 3 | 0 | 3 |
| SLC10A7 | QRICH1 | 0.74346 | 4 | 0 | 4 |
| SLC10A7 | UNC5B | 0.739405 | 3 | 0 | 3 |
| SLC10A7 | KDM5B | 0.737861 | 3 | 0 | 3 |
| SLC10A7 | GLOD4 | 0.736754 | 3 | 0 | 3 |
For details and further investigation, click here
