| Full name: peptidylprolyl isomerase D | Alias Symbol: CYP-40 | ||
| Type: protein-coding gene | Cytoband: 4q32.1 | ||
| Entrez ID: 5481 | HGNC ID: HGNC:9257 | Ensembl Gene: ENSG00000171497 | OMIM ID: 601753 |
| Drug and gene relationship at DGIdb | |||
Expression of PPID:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPID | 5481 | 204185_x_at | -0.1350 | 0.7963 | |
| GSE20347 | PPID | 5481 | 204185_x_at | 0.1242 | 0.5231 | |
| GSE23400 | PPID | 5481 | 204185_x_at | 0.3836 | 0.0000 | |
| GSE26886 | PPID | 5481 | 204185_x_at | -0.4135 | 0.0344 | |
| GSE29001 | PPID | 5481 | 204185_x_at | 0.0042 | 0.9916 | |
| GSE38129 | PPID | 5481 | 204185_x_at | 0.1325 | 0.3040 | |
| GSE45670 | PPID | 5481 | 204185_x_at | 0.2321 | 0.1682 | |
| GSE53622 | PPID | 5481 | 105572 | 0.1530 | 0.0256 | |
| GSE53624 | PPID | 5481 | 105572 | 0.2277 | 0.0180 | |
| GSE63941 | PPID | 5481 | 204185_x_at | 0.2790 | 0.5014 | |
| GSE77861 | PPID | 5481 | 204185_x_at | 0.0061 | 0.9807 | |
| GSE97050 | PPID | 5481 | A_23_P386411 | -0.1770 | 0.4529 | |
| SRP007169 | PPID | 5481 | RNAseq | 1.1972 | 0.0062 | |
| SRP008496 | PPID | 5481 | RNAseq | 1.2548 | 0.0001 | |
| SRP064894 | PPID | 5481 | RNAseq | 0.1843 | 0.1598 | |
| SRP133303 | PPID | 5481 | RNAseq | 0.5637 | 0.0001 | |
| SRP159526 | PPID | 5481 | RNAseq | 0.2298 | 0.2333 | |
| SRP193095 | PPID | 5481 | RNAseq | 0.0106 | 0.9220 | |
| SRP219564 | PPID | 5481 | RNAseq | -0.2848 | 0.4534 | |
| TCGA | PPID | 5481 | RNAseq | 0.0526 | 0.3639 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PPID expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPID:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPID | 5481 | 0 | 13 | 17 | |
| GSE20123 | PPID | 5481 | 0 | 13 | 17 | |
| GSE43470 | PPID | 5481 | 0 | 14 | 29 | |
| GSE46452 | PPID | 5481 | 1 | 36 | 22 | |
| GSE47630 | PPID | 5481 | 0 | 23 | 17 | |
| GSE54993 | PPID | 5481 | 10 | 0 | 60 | |
| GSE54994 | PPID | 5481 | 1 | 12 | 40 | |
| GSE60625 | PPID | 5481 | 0 | 1 | 10 | |
| GSE74703 | PPID | 5481 | 0 | 12 | 24 | |
| GSE74704 | PPID | 5481 | 0 | 6 | 14 | |
| TCGA | PPID | 5481 | 12 | 35 | 49 |
Total number of gains: 24; Total number of losses: 165; Total Number of normals: 299.
Somatic mutations of PPID:
Generating mutation plots.
Highly correlated genes for PPID:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPID | AP3M1 | 0.785196 | 3 | 0 | 3 |
| PPID | NHS | 0.784854 | 3 | 0 | 3 |
| PPID | WDR7 | 0.77004 | 3 | 0 | 3 |
| PPID | RWDD4 | 0.766532 | 3 | 0 | 3 |
| PPID | LYRM7 | 0.763743 | 3 | 0 | 3 |
| PPID | FBXW11 | 0.763234 | 3 | 0 | 3 |
| PPID | FDXACB1 | 0.76181 | 3 | 0 | 3 |
| PPID | CLTA | 0.731704 | 3 | 0 | 3 |
| PPID | CCDC66 | 0.729173 | 3 | 0 | 3 |
| PPID | TMX4 | 0.728191 | 3 | 0 | 3 |
| PPID | GLUD2 | 0.719762 | 3 | 0 | 3 |
| PPID | EIF4ENIF1 | 0.71935 | 3 | 0 | 3 |
| PPID | GLCCI1 | 0.71373 | 3 | 0 | 3 |
| PPID | CGGBP1 | 0.713407 | 3 | 0 | 3 |
| PPID | SLC35A3 | 0.709011 | 3 | 0 | 3 |
| PPID | MRPL27 | 0.705795 | 3 | 0 | 3 |
| PPID | SETD7 | 0.703897 | 3 | 0 | 3 |
| PPID | NDUFB6 | 0.70022 | 4 | 0 | 3 |
| PPID | MRPL37 | 0.697237 | 4 | 0 | 3 |
| PPID | PCDH18 | 0.696415 | 3 | 0 | 3 |
For details and further investigation, click here
