| Full name: minichromosome maintenance complex binding protein | Alias Symbol: FLJ13081|MCM-BP | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 79892 | HGNC ID: HGNC:25782 | Ensembl Gene: ENSG00000197771 | OMIM ID: 610909 |
Screen Evidence:
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Expression of MCMBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCMBP | 79892 | 222464_s_at | 0.3420 | 0.2195 | |
| GSE20347 | MCMBP | 79892 | 217905_at | 0.0895 | 0.5879 | |
| GSE23400 | MCMBP | 79892 | 217905_at | 0.1605 | 0.0004 | |
| GSE26886 | MCMBP | 79892 | 222464_s_at | 0.5764 | 0.0017 | |
| GSE29001 | MCMBP | 79892 | 217905_at | 0.3347 | 0.1692 | |
| GSE38129 | MCMBP | 79892 | 217905_at | 0.1897 | 0.0780 | |
| GSE45670 | MCMBP | 79892 | 222464_s_at | 0.1213 | 0.4222 | |
| GSE53622 | MCMBP | 79892 | 132301 | -0.0937 | 0.2887 | |
| GSE53624 | MCMBP | 79892 | 18343 | 0.3893 | 0.0002 | |
| GSE63941 | MCMBP | 79892 | 222464_s_at | 1.1348 | 0.0009 | |
| GSE77861 | MCMBP | 79892 | 222464_s_at | 0.1776 | 0.5893 | |
| GSE97050 | MCMBP | 79892 | A_33_P3408943 | 0.3794 | 0.2144 | |
| SRP007169 | MCMBP | 79892 | RNAseq | -0.0643 | 0.8586 | |
| SRP008496 | MCMBP | 79892 | RNAseq | -0.0421 | 0.8501 | |
| SRP064894 | MCMBP | 79892 | RNAseq | -0.0717 | 0.6259 | |
| SRP133303 | MCMBP | 79892 | RNAseq | 0.3668 | 0.0142 | |
| SRP159526 | MCMBP | 79892 | RNAseq | 0.1224 | 0.6840 | |
| SRP193095 | MCMBP | 79892 | RNAseq | 0.1985 | 0.0547 | |
| SRP219564 | MCMBP | 79892 | RNAseq | 0.1570 | 0.4843 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MCMBP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MCMBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MCMBP | 79892 | 2 | 8 | 20 | |
| GSE20123 | MCMBP | 79892 | 2 | 8 | 20 | |
| GSE43470 | MCMBP | 79892 | 0 | 9 | 34 | |
| GSE46452 | MCMBP | 79892 | 0 | 11 | 48 | |
| GSE47630 | MCMBP | 79892 | 2 | 14 | 24 | |
| GSE54993 | MCMBP | 79892 | 8 | 0 | 62 | |
| GSE54994 | MCMBP | 79892 | 1 | 9 | 43 | |
| GSE60625 | MCMBP | 79892 | 0 | 0 | 11 | |
| GSE74703 | MCMBP | 79892 | 0 | 6 | 30 | |
| GSE74704 | MCMBP | 79892 | 1 | 3 | 16 | |
| TCGA | MCMBP | 79892 | 4 | 28 | 64 |
Total number of gains: 20; Total number of losses: 96; Total Number of normals: 372.
Somatic mutations of MCMBP:
Generating mutation plots.
Highly correlated genes for MCMBP:
Showing top 20/1212 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCMBP | RAD18 | 0.841942 | 3 | 0 | 3 |
| MCMBP | FAM53B | 0.831234 | 3 | 0 | 3 |
| MCMBP | E4F1 | 0.811974 | 3 | 0 | 3 |
| MCMBP | PACS1 | 0.802223 | 3 | 0 | 3 |
| MCMBP | SUV39H1 | 0.795431 | 3 | 0 | 3 |
| MCMBP | CWF19L1 | 0.794073 | 6 | 0 | 6 |
| MCMBP | TTLL4 | 0.78791 | 3 | 0 | 3 |
| MCMBP | FTSJ1 | 0.782725 | 4 | 0 | 3 |
| MCMBP | BAG4 | 0.779349 | 3 | 0 | 3 |
| MCMBP | ESCO1 | 0.77774 | 4 | 0 | 3 |
| MCMBP | SAMD1 | 0.773672 | 3 | 0 | 3 |
| MCMBP | TSEN15 | 0.771467 | 3 | 0 | 3 |
| MCMBP | PIGU | 0.769224 | 3 | 0 | 3 |
| MCMBP | QTRT1 | 0.767632 | 3 | 0 | 3 |
| MCMBP | UHRF1BP1 | 0.766832 | 4 | 0 | 3 |
| MCMBP | ZNF680 | 0.76518 | 3 | 0 | 3 |
| MCMBP | MRPS26 | 0.762708 | 3 | 0 | 3 |
| MCMBP | IFT80 | 0.761589 | 3 | 0 | 3 |
| MCMBP | COMMD7 | 0.760459 | 3 | 0 | 3 |
| MCMBP | GPR160 | 0.759714 | 3 | 0 | 3 |
For details and further investigation, click here
