| Full name: neurogenin 1 | Alias Symbol: AKA|Math4C|ngn1|bHLHa6 | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 4762 | HGNC ID: HGNC:7764 | Ensembl Gene: ENSG00000181965 | OMIM ID: 601726 |
| Drug and gene relationship at DGIdb | |||
Expression of NEUROG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEUROG1 | 4762 | 208497_x_at | -0.0069 | 0.9813 | |
| GSE20347 | NEUROG1 | 4762 | 208497_x_at | -0.0138 | 0.8657 | |
| GSE23400 | NEUROG1 | 4762 | 208497_x_at | -0.1441 | 0.0000 | |
| GSE26886 | NEUROG1 | 4762 | 208497_x_at | 0.1920 | 0.0904 | |
| GSE29001 | NEUROG1 | 4762 | 208497_x_at | -0.0535 | 0.6751 | |
| GSE38129 | NEUROG1 | 4762 | 208497_x_at | -0.1258 | 0.1022 | |
| GSE45670 | NEUROG1 | 4762 | 208497_x_at | 0.0056 | 0.9444 | |
| GSE53622 | NEUROG1 | 4762 | 5313 | 0.1583 | 0.1285 | |
| GSE53624 | NEUROG1 | 4762 | 5313 | 0.1486 | 0.3045 | |
| GSE63941 | NEUROG1 | 4762 | 208497_x_at | -0.0639 | 0.6015 | |
| GSE77861 | NEUROG1 | 4762 | 208497_x_at | -0.0227 | 0.8557 | |
| GSE97050 | NEUROG1 | 4762 | A_33_P3420680 | 0.1332 | 0.5675 | |
| TCGA | NEUROG1 | 4762 | RNAseq | 3.1786 | 0.0108 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NEUROG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEUROG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEUROG1 | 4762 | 3 | 11 | 16 | |
| GSE20123 | NEUROG1 | 4762 | 4 | 11 | 15 | |
| GSE43470 | NEUROG1 | 4762 | 4 | 5 | 34 | |
| GSE46452 | NEUROG1 | 4762 | 0 | 27 | 32 | |
| GSE47630 | NEUROG1 | 4762 | 0 | 21 | 19 | |
| GSE54993 | NEUROG1 | 4762 | 9 | 1 | 60 | |
| GSE54994 | NEUROG1 | 4762 | 3 | 13 | 37 | |
| GSE60625 | NEUROG1 | 4762 | 0 | 0 | 11 | |
| GSE74703 | NEUROG1 | 4762 | 3 | 4 | 29 | |
| GSE74704 | NEUROG1 | 4762 | 3 | 5 | 12 | |
| TCGA | NEUROG1 | 4762 | 4 | 36 | 56 |
Total number of gains: 33; Total number of losses: 134; Total Number of normals: 321.
Somatic mutations of NEUROG1:
Generating mutation plots.
Highly correlated genes for NEUROG1:
Showing top 20/681 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEUROG1 | ZNF843 | 0.769495 | 3 | 0 | 3 |
| NEUROG1 | MIIP | 0.768615 | 3 | 0 | 3 |
| NEUROG1 | TMEM229A | 0.767801 | 3 | 0 | 3 |
| NEUROG1 | LRFN4 | 0.76353 | 3 | 0 | 3 |
| NEUROG1 | PRKAR1B | 0.755529 | 3 | 0 | 3 |
| NEUROG1 | MUC3A | 0.752081 | 3 | 0 | 3 |
| NEUROG1 | SERTM1 | 0.745593 | 3 | 0 | 3 |
| NEUROG1 | NLRP13 | 0.736961 | 3 | 0 | 3 |
| NEUROG1 | PSMB11 | 0.736742 | 3 | 0 | 3 |
| NEUROG1 | PGC | 0.731041 | 4 | 0 | 3 |
| NEUROG1 | MYOD1 | 0.730266 | 8 | 0 | 8 |
| NEUROG1 | C10orf91 | 0.721896 | 3 | 0 | 3 |
| NEUROG1 | MEGF10 | 0.718233 | 3 | 0 | 3 |
| NEUROG1 | GPR61 | 0.71452 | 3 | 0 | 3 |
| NEUROG1 | C19orf81 | 0.704607 | 3 | 0 | 3 |
| NEUROG1 | ZNF497 | 0.700286 | 3 | 0 | 3 |
| NEUROG1 | TCTEX1D4 | 0.693828 | 3 | 0 | 3 |
| NEUROG1 | WDR90 | 0.690182 | 3 | 0 | 3 |
| NEUROG1 | RCOR2 | 0.68975 | 3 | 0 | 3 |
| NEUROG1 | IQCF2 | 0.686846 | 3 | 0 | 3 |
For details and further investigation, click here
