| Full name: NLR family pyrin domain containing 13 | Alias Symbol: NOD14|PAN13|CLR19.7 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 126204 | HGNC ID: HGNC:22937 | Ensembl Gene: ENSG00000173572 | OMIM ID: 609660 |
| Drug and gene relationship at DGIdb | |||
Expression of NLRP13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NLRP13 | 126204 | 1553525_at | -0.1040 | 0.7447 | |
| GSE26886 | NLRP13 | 126204 | 1553525_at | 0.0963 | 0.4100 | |
| GSE45670 | NLRP13 | 126204 | 1553525_at | 0.1415 | 0.2287 | |
| GSE53622 | NLRP13 | 126204 | 144136 | 0.1102 | 0.2767 | |
| GSE53624 | NLRP13 | 126204 | 144136 | 0.0467 | 0.6791 | |
| GSE63941 | NLRP13 | 126204 | 1553525_at | 0.0027 | 0.9885 | |
| GSE77861 | NLRP13 | 126204 | 1553525_at | -0.0413 | 0.7184 | |
| GSE97050 | NLRP13 | 126204 | A_23_P399834 | 0.0238 | 0.9160 | |
| TCGA | NLRP13 | 126204 | RNAseq | 1.6997 | 0.3462 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NLRP13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NLRP13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NLRP13 | 126204 | 3 | 4 | 23 | |
| GSE20123 | NLRP13 | 126204 | 3 | 3 | 24 | |
| GSE43470 | NLRP13 | 126204 | 3 | 9 | 31 | |
| GSE46452 | NLRP13 | 126204 | 45 | 1 | 13 | |
| GSE47630 | NLRP13 | 126204 | 8 | 6 | 26 | |
| GSE54993 | NLRP13 | 126204 | 17 | 4 | 49 | |
| GSE54994 | NLRP13 | 126204 | 4 | 13 | 36 | |
| GSE60625 | NLRP13 | 126204 | 9 | 0 | 2 | |
| GSE74703 | NLRP13 | 126204 | 3 | 6 | 27 | |
| GSE74704 | NLRP13 | 126204 | 3 | 1 | 16 | |
| TCGA | NLRP13 | 126204 | 19 | 16 | 61 |
Total number of gains: 117; Total number of losses: 63; Total Number of normals: 308.
Somatic mutations of NLRP13:
Generating mutation plots.
Highly correlated genes for NLRP13:
Showing top 20/28 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NLRP13 | NEUROG1 | 0.736961 | 3 | 0 | 3 |
| NLRP13 | S100A5 | 0.724186 | 3 | 0 | 3 |
| NLRP13 | GPT | 0.720877 | 3 | 0 | 3 |
| NLRP13 | BCL2L10 | 0.709793 | 3 | 0 | 3 |
| NLRP13 | LIM2 | 0.678347 | 3 | 0 | 3 |
| NLRP13 | TM6SF2 | 0.675932 | 3 | 0 | 3 |
| NLRP13 | LRFN4 | 0.675047 | 3 | 0 | 3 |
| NLRP13 | SPACA1 | 0.674549 | 3 | 0 | 3 |
| NLRP13 | PAFAH2 | 0.659961 | 3 | 0 | 3 |
| NLRP13 | CTSE | 0.650152 | 4 | 0 | 3 |
| NLRP13 | GPR78 | 0.649184 | 3 | 0 | 3 |
| NLRP13 | GALK2 | 0.64831 | 3 | 0 | 3 |
| NLRP13 | SLC39A5 | 0.637484 | 4 | 0 | 3 |
| NLRP13 | TRH | 0.633775 | 4 | 0 | 3 |
| NLRP13 | SLC30A3 | 0.630736 | 3 | 0 | 3 |
| NLRP13 | CATSPER3 | 0.614957 | 4 | 0 | 3 |
| NLRP13 | TAS2R3 | 0.604988 | 4 | 0 | 4 |
| NLRP13 | MT3 | 0.601098 | 4 | 0 | 3 |
| NLRP13 | SPTB | 0.592475 | 4 | 0 | 3 |
| NLRP13 | FIGLA | 0.581587 | 4 | 0 | 3 |
For details and further investigation, click here
