| Full name: NHL repeat containing 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q13.3 | ||
| Entrez ID: 387921 | HGNC ID: HGNC:33751 | Ensembl Gene: ENSG00000188811 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NHLRC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NHLRC3 | 387921 | 227040_at | -0.0039 | 0.9941 | |
| GSE26886 | NHLRC3 | 387921 | 227040_at | 0.6496 | 0.0456 | |
| GSE45670 | NHLRC3 | 387921 | 227040_at | -0.2847 | 0.1897 | |
| GSE53622 | NHLRC3 | 387921 | 124189 | -0.0127 | 0.9024 | |
| GSE53624 | NHLRC3 | 387921 | 124189 | -0.0994 | 0.1452 | |
| GSE63941 | NHLRC3 | 387921 | 227040_at | -0.6387 | 0.2380 | |
| GSE77861 | NHLRC3 | 387921 | 227040_at | -0.0091 | 0.9785 | |
| GSE97050 | NHLRC3 | 387921 | A_32_P129950 | -0.0625 | 0.7792 | |
| SRP007169 | NHLRC3 | 387921 | RNAseq | 0.2733 | 0.5557 | |
| SRP008496 | NHLRC3 | 387921 | RNAseq | 0.3095 | 0.2928 | |
| SRP064894 | NHLRC3 | 387921 | RNAseq | 0.1502 | 0.4773 | |
| SRP133303 | NHLRC3 | 387921 | RNAseq | -0.1650 | 0.2962 | |
| SRP159526 | NHLRC3 | 387921 | RNAseq | -0.5949 | 0.0579 | |
| SRP193095 | NHLRC3 | 387921 | RNAseq | -0.4368 | 0.0011 | |
| SRP219564 | NHLRC3 | 387921 | RNAseq | -0.1547 | 0.5951 | |
| TCGA | NHLRC3 | 387921 | RNAseq | -0.2996 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NHLRC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NHLRC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NHLRC3 | 387921 | 0 | 16 | 14 | |
| GSE20123 | NHLRC3 | 387921 | 0 | 15 | 15 | |
| GSE43470 | NHLRC3 | 387921 | 3 | 13 | 27 | |
| GSE46452 | NHLRC3 | 387921 | 0 | 33 | 26 | |
| GSE47630 | NHLRC3 | 387921 | 2 | 27 | 11 | |
| GSE54993 | NHLRC3 | 387921 | 12 | 2 | 56 | |
| GSE54994 | NHLRC3 | 387921 | 1 | 17 | 35 | |
| GSE60625 | NHLRC3 | 387921 | 0 | 3 | 8 | |
| GSE74703 | NHLRC3 | 387921 | 3 | 10 | 23 | |
| GSE74704 | NHLRC3 | 387921 | 0 | 12 | 8 | |
| TCGA | NHLRC3 | 387921 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 188; Total Number of normals: 272.
Somatic mutations of NHLRC3:
Generating mutation plots.
Highly correlated genes for NHLRC3:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NHLRC3 | SUPT20H | 0.680203 | 4 | 0 | 4 |
| NHLRC3 | KANSL1 | 0.6329 | 3 | 0 | 3 |
| NHLRC3 | ZC3H13 | 0.622249 | 5 | 0 | 4 |
| NHLRC3 | MDM4 | 0.621524 | 3 | 0 | 3 |
| NHLRC3 | CHIC1 | 0.618853 | 3 | 0 | 3 |
| NHLRC3 | RBM26 | 0.60972 | 5 | 0 | 4 |
| NHLRC3 | N4BP2L2 | 0.604671 | 6 | 0 | 5 |
| NHLRC3 | GPALPP1 | 0.602707 | 6 | 0 | 4 |
| NHLRC3 | KCTD18 | 0.602275 | 3 | 0 | 3 |
| NHLRC3 | CPD | 0.60183 | 5 | 0 | 3 |
| NHLRC3 | TTC17 | 0.600406 | 3 | 0 | 3 |
| NHLRC3 | CCDC149 | 0.593656 | 4 | 0 | 3 |
| NHLRC3 | ARMCX3 | 0.582207 | 5 | 0 | 4 |
| NHLRC3 | EPC2 | 0.5806 | 5 | 0 | 4 |
| NHLRC3 | NIFK-AS1 | 0.575936 | 4 | 0 | 3 |
| NHLRC3 | ZNF587 | 0.575785 | 3 | 0 | 3 |
| NHLRC3 | DCUN1D4 | 0.571795 | 4 | 0 | 3 |
| NHLRC3 | MPHOSPH8 | 0.570548 | 5 | 0 | 4 |
| NHLRC3 | RNF115 | 0.565521 | 4 | 0 | 3 |
| NHLRC3 | UTP14C | 0.561623 | 3 | 0 | 3 |
For details and further investigation, click here
