| Full name: potassium channel tetramerization domain containing 18 | Alias Symbol: FLJ31322|6530404F10Rik|FLJ37818 | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 130535 | HGNC ID: HGNC:26446 | Ensembl Gene: ENSG00000155729 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KCTD18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCTD18 | 130535 | 226493_at | -0.3542 | 0.2216 | |
| GSE26886 | KCTD18 | 130535 | 226493_at | -0.4619 | 0.2072 | |
| GSE45670 | KCTD18 | 130535 | 226493_at | -0.1147 | 0.5747 | |
| GSE53622 | KCTD18 | 130535 | 54561 | -0.2311 | 0.0063 | |
| GSE53624 | KCTD18 | 130535 | 54561 | -0.3283 | 0.0000 | |
| GSE63941 | KCTD18 | 130535 | 226493_at | -0.8633 | 0.0246 | |
| GSE77861 | KCTD18 | 130535 | 226493_at | -0.1191 | 0.7409 | |
| GSE97050 | KCTD18 | 130535 | A_23_P309515 | 0.1436 | 0.4977 | |
| SRP007169 | KCTD18 | 130535 | RNAseq | -0.9818 | 0.0308 | |
| SRP008496 | KCTD18 | 130535 | RNAseq | -0.4906 | 0.0973 | |
| SRP064894 | KCTD18 | 130535 | RNAseq | -0.3920 | 0.0592 | |
| SRP133303 | KCTD18 | 130535 | RNAseq | -0.2619 | 0.0518 | |
| SRP159526 | KCTD18 | 130535 | RNAseq | -0.3823 | 0.0840 | |
| SRP193095 | KCTD18 | 130535 | RNAseq | -0.2970 | 0.0021 | |
| SRP219564 | KCTD18 | 130535 | RNAseq | -0.5723 | 0.1342 | |
| TCGA | KCTD18 | 130535 | RNAseq | -0.1040 | 0.0593 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KCTD18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCTD18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCTD18 | 130535 | 6 | 4 | 20 | |
| GSE20123 | KCTD18 | 130535 | 6 | 4 | 20 | |
| GSE43470 | KCTD18 | 130535 | 2 | 1 | 40 | |
| GSE46452 | KCTD18 | 130535 | 1 | 4 | 54 | |
| GSE47630 | KCTD18 | 130535 | 4 | 5 | 31 | |
| GSE54993 | KCTD18 | 130535 | 0 | 3 | 67 | |
| GSE54994 | KCTD18 | 130535 | 10 | 8 | 35 | |
| GSE60625 | KCTD18 | 130535 | 0 | 3 | 8 | |
| GSE74703 | KCTD18 | 130535 | 2 | 1 | 33 | |
| GSE74704 | KCTD18 | 130535 | 3 | 2 | 15 | |
| TCGA | KCTD18 | 130535 | 23 | 10 | 63 |
Total number of gains: 57; Total number of losses: 45; Total Number of normals: 386.
Somatic mutations of KCTD18:
Generating mutation plots.
Highly correlated genes for KCTD18:
Showing top 20/347 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCTD18 | FASTKD2 | 0.800872 | 3 | 0 | 3 |
| KCTD18 | FNDC3A | 0.758841 | 3 | 0 | 3 |
| KCTD18 | SCAF8 | 0.754191 | 3 | 0 | 3 |
| KCTD18 | RAPGEF6 | 0.753001 | 3 | 0 | 3 |
| KCTD18 | STEAP4 | 0.751082 | 3 | 0 | 3 |
| KCTD18 | FPGT | 0.750918 | 3 | 0 | 3 |
| KCTD18 | CDIPT | 0.74521 | 3 | 0 | 3 |
| KCTD18 | KIAA1191 | 0.731554 | 3 | 0 | 3 |
| KCTD18 | MTRF1 | 0.72625 | 3 | 0 | 3 |
| KCTD18 | C1orf56 | 0.722616 | 3 | 0 | 3 |
| KCTD18 | KIF13B | 0.722546 | 3 | 0 | 3 |
| KCTD18 | TTC14 | 0.719998 | 3 | 0 | 3 |
| KCTD18 | CD44 | 0.716492 | 3 | 0 | 3 |
| KCTD18 | SLC30A9 | 0.712287 | 4 | 0 | 4 |
| KCTD18 | C21orf91 | 0.710795 | 4 | 0 | 4 |
| KCTD18 | NUDT18 | 0.708642 | 3 | 0 | 3 |
| KCTD18 | SCAPER | 0.706749 | 5 | 0 | 5 |
| KCTD18 | HAUS1 | 0.706328 | 3 | 0 | 3 |
| KCTD18 | FOPNL | 0.701025 | 3 | 0 | 3 |
| KCTD18 | RRAGA | 0.696883 | 3 | 0 | 3 |
For details and further investigation, click here
